Comparative Analysis of the Efficiency of Medicinal Plants for the Treatment and Prevention of COVID-19

Abstract

The COVID-19 pandemic has once again prompted people to resort to the remedies of folk and alternative medicine. Medicinal plants, because of their chemical composition, pharmacological properties, and the action of biologically active substances, can stop and relieve the symptoms of the disease. The purpose of the work is a comparative flora analysis of medicinal plants to identify the most prospective plant and further production of a remedy for the avoidance, treatment, and rehabilitation of COVID-19. The search for prospective medicinal plants was performed by analyzing the literature in online databases: Web of Science, Scopus, Google Scholar, and PubMed, including official WHO media sites. According to recent studies related to COVID-19, a significant number of medicinal plants with anti-inflammatory, antiviral, and immunostimulatory effects have been identified. A comparative study of nine medicinal plants was conducted to determine the most suitable medicinal plant to treat coronavirus infection. According to the results of the comparative analysis, Chamaenerion angustifolium Seg. showed itself as the most prospective medicinal plant with the greatest pharmacological effect compared with other types of medicinal plants. Its therapeutic properties allow physiological relief of 18 symptoms of coronavirus infection. It is advisable to conduct further clinical trials for the treatment and rehabilitation of COVID-19 using preparations from this plant.

Exploring the Potential and Limitations of Medicinal Plants in COVID-19 Management: Insights from Algeria

“…For many individuals, herbal remedies serve as the primary, and sometimes sole, source of medical care, owing to their territorial accessibility and financial feasibility. Moreover, amid the COVID-19 pandemic, the affordability and accessibility of most herbal remedies have amplified their appeal compared to conventional medicines [24] . Fan et al [25] in their review of seven clinical trials involving 736 COVID-19 patients, collectively demonstrated that the use of Chinese herbal medicine as adjunctive therapy alongside standard care improved treatment outcomes in COVID-19 cases.…”

In Vitro Assessment of Antioxidant Capacity, Potential to Induce Autophagy/Mitophagy, and Mitochondrial Turnover of Natural Compounds for Cytotoxicity Studies

“…Spices and herbs that are sources of natural antioxidants, can protect against oxidative stress and thus play preventive role in many diseases [13]. The medicinal properties of folk plants are mainly attributed to the presence of flavonoids, other organic, and inorganic compounds such as coumarins, phenolic acids, and antioxidant micronutrients and are able to counter various metabolic disorders, cancers, and COVID-19 [14][15][16][17].…”

Immunomodulatory properties of plants of the genus Filipendula

“…Однако ряд растений из этномедицинских баз данных находятся в лабораторных условиях по всему миру, среди которых и растения рода Filipendula. Из приведенных выше данных можно сделать вывод, что экстракты из растений рода Filipendula обладают интересными противовоспалительными свойствами, которые представляют большой потенциал для терапевтической практики человека [40] и при том не только в сфере иммуномодулирующего действия. Салицилаты не являются единственными интересными соединениями в этих растениях, наличие аскорбиновой кислоты способствует общеукрепляющему действию на организм.…”