Comparative analysis of three kinds of extraction kinetic models of crude polysaccharides from Codonopsis pilosula and evaluate the characteristics of crude polysaccharides

Abstract

In this study, the second-order model, Fick’s second law of diffusion, and the Peleg model were used to evaluate the extraction kinetic model of polysaccharide (CPP) from Codonopsis pilosula . The characteristic functional groups, surface structure, and physical and chemical properties of CPP were analyzed by multi-spectroscopic and microscopic techniques. The results showed that the extraction process agreed well with the second-order model, Fick’s second diffusion law, and Peleg model. Rheological tests showed that CPP exhibited different viscosity changes under different conditions (Solution viscosity was inversely proportional to temperature, time, etc.; proportional to polysaccharide concentration, Na + content, etc.). CPP was composed of molecular aggregates composed of small particles, with more pore structure and basically completely decomposed at 130 °C. The hypoglycemic study showed that CPP had a strong inhibitory effect on α-glycosidase than α-amylase. The morphology and subsequent structural features, anti-diabetic potential, and rheological properties of CPP were revealed to provide a theoretical basis for the development of pharmaceutical preparations or health food and functional food for the treatment of diabetes. Graphic Abstract Supplementary Information The online version contains supplementary material available at 10.1007/s13399-022-02518-w.

Response Surface Methodology Applied to the Optimization of the Preparation of Antioxidant and Antidiabetic Extracts from Phragmanthera capitata (Spreng.) Balle: Effect of Particle Size, Powder-to-Solvent Ratio, and Temperature

“…Makanjuola et al [ 40 ] reported that the phenolic content and antioxidant properties in ground tea with particle sizes of 0.425 mm were higher than those in ground tea with particle sizes of 1.180 mm. A rapid increase in polysaccharide yield was observed when the particle size of Codonopsis pilosula powder decreased from 420 to 180 μ m, and the optimal particle size was 180 μ m; the maximum polysaccharide yield was 15.56% [ 41 ]. In contrast, catechin content and antioxidant properties in hydroalcoholic extracts of green tea decreased for particles of sizes less than 50 μ m, showing that the smallest particles can sediment and decrease the contact between particles and the extraction solvent, thereby reducing mass transfer efficiency [ 42 ].…”

Kinetic modeling for microwave-assisted green extraction: Effects of power on citronella oil from Cymbopogon nardus leaf

“…In addition to expressions derived from Fick's law, the adapted second-order rate law has also been employed for extraction modeling (Jabar et al, 2015;Wang et al, 2022). A distinct extraction kinetic for microwave-assisted processes has been highlighted by another report (Lee et al, 2016), owing to its significant increase in the obtained extraction yields at a reduced time as compared to the conventional extraction method.…”

Anticancer Podophyllotoxin Recovery from Juniper Leaves at Atmospheric and High Pressure Using Eco-Friendly Solvents

“…Originally, Peleg’s kinetic model was meant to describe the absorption processes. However, due to a similar asymptotic shape of the sorption and extraction kinetic curves, this modeling was widely applied for the description of the extraction curves (e.g., analysis of the extracted matter over time) of bioactive substances from plants [ 23 , 24 ]. PPT quantification in the juniper leaf extracts was carried out using HRMS/MS detection.…”