Comparative effect of Freund's adjuvant andAloe veraL. gel on the expression of TNF-α and IL-1β in vaccinatedCyprinus carpioL. withAeromonas hydrophilaC. bacterin

Abdy, Esmail; Alishahi, Mojtaba; Tabandeh, Mohammad Reza; Ghorbanpoor, Masoud; Jafari, Hadis

doi:10.1111/are.12702

Cited by 7 publications

(3 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The positive modulation of TNF-α has been observed in specimens of Cyprinus carpio treated, during vaccination, with Aloe vera, and also on immunity response in poultry, mice, and humans [35]. In that case, the effects were attributed to some poorly defined compounds of the plant [35].…”

Section: Discussionmentioning

confidence: 97%

“…Regarding the variation of the liver biomolecular markers related to general stress response and immunostimulation, in this case the increase of TNF-α could also be ascribed to a significant production of mediators of inflammation, acting as a strategy of protection [34]. The positive modulation of TNF-α has been observed in specimens of Cyprinus carpio treated, during vaccination, with Aloe vera, and also on immunity response in poultry, mice, and humans [35]. In that case, the effects were attributed to some poorly defined compounds of the plant [35].…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Related to Health and Stress

Panettieri

Chatzifotis

Messina

et al. 2020

Animals

View full text Add to dashboard Cite

This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles’ diets on growth performance, diet digestibility, intestinal morphology, and immunohistochemistry. Furthermore, stress-related molecular markers and biochemical blood profile of fish were evaluated, together with mineral trace and toxic element concentration in pollen and diets. Specimens of meagre (360) of 3.34 ± 0.14 g initial body weight, were randomly allocated to twelve 500 L circular tanks (30 fish per tank). Four diets were formulated: a control diet and three experimental diets with 1%, 2.5%, and 4% of HBP inclusion. All the growth parameters and crude protein and ether extract digestibility coefficients were negatively linearly affected by increased HBP inclusion (p < 0.0001). Histology of medium intestine showed slight signs of alterations in group HPB1 and HPB2.5 compared to control. Fish from HBP4 group showed severe alterations at the intestinal mucosa level. Immunohistochemical detection of TNF-α in the medium intestine showed the presence of TNF-α+ cells in the lamina propria, which resulted in accordance with the increased level of the TNF-α protein detected by immunoblotting in the liver. This stress situation was confirmed by the increased hepatic level of HSP70 (p < 0.05) in fish fed the HBP4 diet and by the linear decrease of total serum protein levels in HBP-containing diets (p < 0.0001). These negative effects can be related to the ultrastructure of the bee pollen grain walls, which make the bioactive substances unavailable and can irritate the intestine of a carnivorous fish such as meagre.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 98%

Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Related to Health and Stress

Panettieri

Chatzifotis

Messina

et al. 2020

Animals

View full text Add to dashboard Cite

show abstract

“…The adjuvant effect was directly compared between incomplete Freund's and Aloe vera gel by immunizing common carp via ip injection with A. hydrophila bacterin (Abdy et al . ). Abdy et al .…”

Section: Medicinal Herbsmentioning

confidence: 97%

Adjuvant effects of medicinal herbs and probiotics for fish vaccines

Soltani

Lymbery

Song

et al. 2018

Reviews in Aquaculture

View full text Add to dashboard Cite

The most prominent limiting factor in aquaculture nowadays is infectious diseases as they lead to massive economic losses. These diseases are often partly controlled by vaccination, herbs or probiotics. Despite the fact that vaccination is the most effective prophylactic approach to disease prevention, researchers have started to use plant-derived products and probiotics as adjuvants to boost the efficacy of fish vaccines. This review describes the efficacy and potency of plant extracts/essences and probiotics as adjuvants for various vaccines in aquaculture.

show abstract