Comparative Effectiveness Research: Betahistine add-on Therapy with Epley’s Manoeuvre Versus Epley’s Manoeuvre Alone in Treating Posterior BPPV Patients

Singh, Garima; Aggarwal, Ankita; Sahni, Dimple; Sharma, Dinesh Kumar; Yadav, Vishav; Bhagat, Sanjeev

doi:10.1007/s12070-022-03369-7

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…But Singh et al did a study titled "comparative effectiveness research: betahistine add-on therapy with Epley's maneuver versus Epley's maneuver alone in treating posterior BPPV patients" and concluded that betahistine therapy in conjunction with Epley's maneuver leads to better symptom control and is more effective than Epley's alone in treating BPPV patients. 20 A study by Janpeet et al concluded that pharmacological therapy with betahistine, when used in conjunction with Epley's, is a safe modality of treatment. Betahistine can be used as the sole modality of treatment in patients of BPPV who are unfit to undergo canalolith repositioning maneuvers.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Epley's maneuver alone without any drugs in the treatment of posterior canal benign paroxysmal positional vertigo: a prospective analytical study

George,

2023

Int J Otorhinolaryngol Head Neck Surg

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Background: Posterior canal benign paroxysmal positional vertigo (p-BPPV) is the most common peripheral vestibular problem. Many doctors use three treatment options for p-BPPV: drugs alone, Epley’s maneuver with drugs, and Epley’s maneuver alone. Many studies say that Epley’s maneuver with drugs improves the condition much more effectively than drugs alone. Our study is intended to assess the effectiveness of Epley’s maneuver alone in treating posterior canal BPPV. Methods: A prospective analytical study was performed on 102 patients who were divided into 2 groups after random sampling. Group I underwent repeated applications of Epley’s maneuver alone, and group II underwent a single Epley’s maneuver along with drugs. The data were collected systematically with the help of a proforma and dizziness handicap inventory (DHI) score chart. The patients were reviewed after 24 hours, 1 week, and 1 month. Results: In our study, the mean pre-treatment DHI score of group I was 66.71, and group II was 64.39. After 24 hours, the DHI score came down to 46 and 47.61 respectively, and after 1 week and 1 month, it decreased to 33.06 and 22.86, respectively in group I and group II, it came to 44.71 and 38.78, respectively. The difference in mean DHI score between groups I and II is statistically significant, with each review having a p value of 0.00. Conclusions: This study was able to demonstrate the efficacy of Epley's maneuver in the treatment of BPPV without any drug.

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Section: Discussionmentioning

confidence: 99%

Effectiveness of Epley's maneuver alone without any drugs in the treatment of posterior canal benign paroxysmal positional vertigo: a prospective analytical study

George,

2023

Int J Otorhinolaryngol Head Neck Surg

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“…Кроме того, лекарственные средства могут применяться симптоматически для уменьшения головокружения и тошноты в процессе репозиционных процедур. В таких случаях за 40-50 мин до процедуры назначают вестибулярные супрессанты (например, дименгидринат) и противорвотные средства (например, метоклопрамид) [36].…”

Section: рецидивирующий вестибулярный синдромunclassified

Patient management with complaints of vertigo at the first visit

Amelin,

Lilenko,

Zamergrad

et al. 2023

Russian Medical Inquiry

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Vertigo and balance disorders are one of the most common causes of patients seeking medical help. Vertigo and balance disorders study primarily consists of the following: complaint report, anamnestic data and neurovestibular study. Currently, an algorithm is used based on the identification of three vestibular syndromes: acute, recurrent and chronic, as well as on the analysis of vertigo triggers and concomitant symptoms. Primarily, it is important to determine which vestibular syndrome is acute, recurrent or chronic at the first patient visit with vertigo and balance disorders. Besides, using the otoneurological examination methods is essential for determining the presence or absence of signs concerning the central nervous system disorder or the labyrinth. At the same time, it should be understood that the nervous system disorders accompanied by vertigo can pose a particular danger to the patient and should be excluded first of all. For the treatment and rehabilitation of patients with vertigo, individual selection of therapy and vestibular rehabilitation programs is most effective, taking into account the origin of vestibular disorder, the progression severity, as well as the age, physical and emotional condition. Vestibular rehabilitation can significantly reduce the vertigo severity and improve resistance indicators in patients with vestibular disorders. To improve vestibular compensation, it is advisable to use drug therapy with betahistine dihydrochloride, 48 mg per day, in a modified-release dosage form for better adherence. KEYWORDS: dizziness, balance disorder, acute vestibular syndrome, chronic vestibular syndrome, recurrent vestibular syndrome, betahistine, neurovestibular study FOR CITATION: Amelin A.V., Lilenko S.V., Zamergrad M.V., Guseva A.L., Zaitseva O.V., Voronov V.A., Demidenko D.Yu., Koreshkina M.I., Ovchinnikov D.A. Patient management with complaints of vertigo at the first visit. Russian Medical Inquiry. 2023;7(10):658–665 (in Russ.). DOI: 10.32364/2587-6821-2023-7-10-8.

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Diagnosis and treatment of dizziness and vertigo in clinical practice

Makarov,

Guseva

2023

Medicinskij alfavit

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The article describes vertigo diagnostic algorithm. Acute, paroxysmal, and chronic vestibular syndromes determination, attacks duration assessment, provoking factors and comorbid diseases are described. The otoneurologic examination main tests and their interpretation in assessing of spontaneous nystagmus, the results of stato-coordination tests, the head rotation test and positional tests are presented. Diagnostic criteria and basic approach to the most common disorders manifested by vertigo treatment are discussed, including benign paroxysmal positional vertigo, vestibular neuronitis, Meniere's disease, vestibular migraine, persistent postural-perceptual vertigo, bilateral vestibulopathy and others.

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Comparative Effectiveness Research: Betahistine add-on Therapy with Epley’s Manoeuvre Versus Epley’s Manoeuvre Alone in Treating Posterior BPPV Patients

Cited by 3 publications

References 19 publications

Effectiveness of Epley's maneuver alone without any drugs in the treatment of posterior canal benign paroxysmal positional vertigo: a prospective analytical study

Effectiveness of Epley's maneuver alone without any drugs in the treatment of posterior canal benign paroxysmal positional vertigo: a prospective analytical study

Patient management with complaints of vertigo at the first visit

Diagnosis and treatment of dizziness and vertigo in clinical practice

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