Comparative efficacy of two single-dose bacterins in the control of Mycoplasma hyopneumoniae in swine raised under commercial conditions in Brazil

Baccaro, Maria Regina; Hirose, Flavio; Umehara, O.; Gonçalves, L. C. B; Doto, Daniela Sabatini; Paixão, Renata; Shinya, Luciane Tieko; Moreno, Andréa Micke

doi:10.1016/j.tvjl.2005.07.012

Cited by 18 publications

(19 citation statements)

References 5 publications

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“…This is in accordance with a study suggesting that weekly assessment of coughing is not a predictive indicator of lung lesions at slaughter [ 28 ]. ADG did not differ between the groups, which is also in accordance with other field studies [ 29 , 30 ]. However, a recent study investigating the impact of lung lesions on production performance showed that each categorial increase in EP-like lesion severity, according to a 5-step scoring system different from the one used in this study, resulted in a reduction of 0.37 kg in post-trimming carcass weight [ 31 ].…”

Section: Discussionsupporting

confidence: 92%

Clinical efficacy of two vaccination strategies against Mycoplasma hyopneumoniae in a pig herd suffering from respiratory disease

Cvjetković¹,

Sipos

Szabó³

et al. 2018

Porc Health Manag

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BackgroundA randomised field trial was conducted on an Austrian farrow-to-finish farm for one year to compare the efficacy of two commercial Mycoplasma hyopneumoniae vaccines. 585 piglets either received the one-shot formulation in group 1 (Hyogen®, 23.9 days of age) or a two-shot vaccine (Stellamune® Mycoplasma, 4.3 and 24.0 days of age) in group 2. Assessment of vaccine efficacy was evaluated by regression analyses through cough monitoring from nursery to slaughter, average daily weight gain from inclusion to slaughter, antibiotic treatment rate (ATR), mortality rate, and lung lesion scoring at slaughter.ResultsIn general, coughing was more frequent during late nursery and finishing. No significant differences were found in the coughing index (0.02 vs 0.03) and mean average daily weight gain (560 vs 550 g) between the two groups. ATR was higher in group 2 (3.8 vs 9.6%). At the slaughterhouse check, significant differences in the prevalence of bronchopneumonia (62.9 vs 71.2%) could be found. Extension of lung lesions was also significantly lower in group 1 in terms of enzootic pneumonia (EP) values (p = 0.000, z = − 4.269). There were no significant differences in the rate of scarred lungs (20.0 vs 24.0%) or those affected by dorsocaudal pleurisy (36.8 vs 34.3%).ConclusionsThis trial demonstrated that Hyogen® was superior to Stellamune® Mycoplasma in reducing (I) the prevalence of bronchopneumonic lungs and those affected by cranioventral pleurisy, (II) the extension and severity of EP-like lung lesions, and (III) the rate of antibiotically treated animals against respiratory disease.

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Section: Discussionsupporting

confidence: 92%

Clinical efficacy of two vaccination strategies against Mycoplasma hyopneumoniae in a pig herd suffering from respiratory disease

Cvjetković¹,

Sipos

Szabó³

et al. 2018

Porc Health Manag

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“…Additionally, vaccination with the intradermal or intramuscular vaccine resulted in a significantly lower lung lesion score at slaughter and considerably more animals without lung lesions in the vaccinated groups than in the control group. Such results, as Baccaro and others 2006 have also suggested, might be due to immune stimulation and lower M hyopneumoniae excretion.…”

Section: Discussionmentioning

confidence: 57%

Clinical evaluation of intradermal vaccination against porcine enzootic pneumonia (Mycoplasma hyopneumoniae)

Tassis

Papatsiros

Nell³

et al. 2012

Veterinary Record

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The aim of the present study was to investigate the efficacy of single-dose intradermal vaccination against Mycoplasma hyopneumoniae on a commercial swine unit. A total of 1051 healthy suckling piglets of 28±3 days of age were randomly assigned to one of three experimental groups: (a) intradermal: 346 piglets vaccinated intradermally (Porcilis M Hyo ID Once, Intervet SPAH), (b) intramuscular : 351 piglets vaccinated intramuscularly (Porcilis M1 Intervet SPAH) and (c) controls: 354 piglets injected with a placebo (adjuvant only). Performance parameters such as average daily weight gain (ADG), as well as health parameters and lung lesion scores were monitored from four weeks of age until slaughter. The improvement in ADG over the controls, during the finishing phase, was 27 g/day for the intradermal group and 17 g/day for the intramuscular group. Both intradermal and intramuscular vaccinations were effective in reducing clinical signs and lung lesions caused by M hyopneumoniae. Compared with the controls, approximately 10.4 per cent fewer clinical cases were diagnosed in the intradermal group, and 6 per cent fewer in the intramuscular group, during the finishing period. In conclusion, performance results were better in the vaccinated groups than in the control group, while intradermal vaccination afforded greater protection than intramuscular vaccination, especially with regard to morbidity, lung lesion and pleuritis scores.

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“…Traditionally, double vaccination was the most frequent practice. During the last years, one-shot vaccines have been shown to confer similar benefits than two-shot vaccines and are more often used now (Baccaro et al, 2006). One-shot vaccination is especially popular because it requires less labor and it can be implemented more easily in routine management practices on the farm.…”

Section: Vaccination Strategiesmentioning

confidence: 99%

Control of Mycoplasma hyopneumoniae infections in pigs

Maes

Segalés

Meyns

et al. 2008

Veterinary Microbiology

361

311

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Mycoplasma hyopneumoniae, the primary pathogen of enzootic pneumonia, occurs worldwide and causes major economic losses to the pig industry. The organism adheres to and damages the ciliated epithelium of the respiratory tract. Affected pigs show chronic coughing, are more susceptible to other respiratory infections and have a reduced performance. Control of the disease can be accomplished in a number of ways. First, management practices and housing conditions in the herd should be optimized. These include all-in/all-out production, limiting factors that may destabilize herd immunity, maintaining optimal stocking densities, prevention of other respiratory diseases, and optimal housing and climatic conditions. Strategic medication with antimicrobials active against M. hyopneumoniae and, preferably, also against major secondary bacteria may be useful during periods when the pigs are at risk for respiratory disease. Finally, commercial bacterins are widely used to control M. hyopneumoniae infections. The main effects of vaccination include less clinical symptoms, lung lesions and medication use, and improved performance. However, bacterins provide only partial protection and do not prevent colonization of the organism. Different vaccination strategies (timing of vaccination, vaccination of sows, vaccination combined with antimicrobial medication) can be used, depending on the type of herd, the production system and management practices, the infection pattern and the preferences of the pig producer. Research on new vaccines is actively occurring, including aerosol and feed-based vaccines as well as subunit and DNA vaccines. Eradication of the infection at herd level based on age-segregation and medication is possible, but there is a permanent risk for re-infections.

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Comparative efficacy of two single-dose bacterins in the control of Mycoplasma hyopneumoniae in swine raised under commercial conditions in Brazil

Cited by 18 publications

References 5 publications

Clinical efficacy of two vaccination strategies against Mycoplasma hyopneumoniae in a pig herd suffering from respiratory disease

Clinical efficacy of two vaccination strategies against Mycoplasma hyopneumoniae in a pig herd suffering from respiratory disease

Clinical evaluation of intradermal vaccination against porcine enzootic pneumonia (Mycoplasma hyopneumoniae)

Control of Mycoplasma hyopneumoniae infections in pigs

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