Comparative evaluation of antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica, Aloe vera) with sodium hypochlorite: An in vitro study

Babaji, Prashant; Jagtap, Kiran; Lau, Himani; Bansal, Nandita; Thajuraj, S; Sondhi, Priti

doi:10.4103/2231-0762.183104

Cited by 42 publications

(53 citation statements)

References 10 publications

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“…Similarly, Babaji et al. () also found that the extract of the M. citrifolia fruit with sodium hypochlorite had antimicrobial activity against Enterococcus faecalis . The results indicate that the extract of the fruit of M. citrifolia has high potential of use as an herbal root canal irrigant.…”

Section: Phytotherapic Propertiesmentioning

confidence: 87%

Properties and Applications of Morinda citrifolia (Noni): A Review

Almeida

Oliveira

Hotza

2019

Comp Rev Food Sci Food Safe

114

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Morinda citrifolia commonly known as noni is a perennial plant originating in Southeast Asia, consumed over 2000 years. Due to its versatility of adaptation and use of the structures of the plant for different therapeutic purposes, noni attracted the attention of researchers from the pharmaceutical and food industry. Chemical and nutritional analyzes already performed in M. citrifolia reveal the existence of more than 200 phytochemical substances with bioactive properties such as acids, alcohols, phenols, saccharides, anthraquinones, carotenoids, esters, triterpenoids, flavonoids, glycosides, lactones, iridoids, ketones, lactones, lignans, nucleosides, triterpenides, sterols, and aromatic compounds. The high nutritional value of M. citrifolia may induce therapeutic effects, including antimicrobial and antioxidant properties. The main industrial products from this plant are beverages (juice drinks), powders (from dried fruits), oil (from seeds), and leaf powders. Biological and phytotherapeutic applications of M. citrifolia are promising, but more extensive studies are still required. Thus, this review aims to gather updated and comprehensive information on Morinda citrifolia, discussing its traditional use, biochemical, phytotherapics, and toxicological properties, as well as the recent advances in the processing and standardization of products derived from noni fruit.

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Section: Phytotherapic Propertiesmentioning

confidence: 87%

Properties and Applications of Morinda citrifolia (Noni): A Review

Almeida

Oliveira

Hotza

2019

Comp Rev Food Sci Food Safe

114

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“…Leaf, fruit and aerial part of M. citrifolia exhibit antimicrobial effect against Escherichia coli, Staphylococcus aureus, Candida albicans , Aspergillus niger, Pseudomonas aeruginosa, Proteus morgaii, Bacillus subtilis, Helicobacter pylori , Enterococcus faecalis , Salmonella and Shigella species (Jainkittivong et al, ; Candida et al, ; Choudhary et al, ; Dhivya, & Santhy, ; Chaitanya et al, ; Babaji, Jagtap, & Lau, ; Bhardwaj, Velmurugan, & Sumitha, ; Usha et al, ; Banerjee, Johnson, Csiszar, Wansley, & McGeady, ). The morinquinone isolated from the stems of M. elliptica possesses weak antimicrobial activity against S. aureus and a methicillin‐resistant S. aureus .…”

Section: Pharmacology Of Indian Morinda Speciesmentioning

confidence: 99%

Indian Morinda species: A review

Singh

Sharma

2019

Phytotherapy Research

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Morinda is a largest genus of Rubiaceae family, and its 11 species are found in India.In India, plant species are known by several common names as great morinda, Indian mulberry, noni, beach mulberry and cheese fruit. Various Morinda products (capsules, tablets, skin products and fruit juices) are available in the market, used by people for treatment of several health complaints. A diversity of phytochemicals including iridoids, flavonoids, flavonoid glycosides, anthraquinones, coumarins, lignanas, noniosides, phenolics and triterpenoids have been reported from Morinda species. Morinda species are used in the treatment of inflammation, cancer, diabetes, psyquiatric disorders, and bacterial and viral infections. The noni fruit juice (Morinda citrifolia) and its products are used clinically in the treatment of cancer, hypertension and cervical spondylosis affecting patients. M. citrifolia fuit juice, with different doses, is used in the maintaining blood pressure and reducing of superoxides, HDL and LDL levels. Similarly, oligosaccharide capsules and tablets of root extract of M. officinalis are recommended as medicine for the treatment of kidney problems and sexual dysfunctions of patients. The toxicological studies revealed that higher doses of fruit juice (4,000 or 5,000 mg/kg) of M. citrifolia for 2 or more months cause toxic effects on liver and kidneys. M. officinalis root extracts (ethanolic and aqueous) are found fully safe during treatment of diseases. A large number of reviews are available on M. citrifolia but very few studies are conducted on other Indian Morinda species. This review reports the comprehensive knowledge on state-wise distribution, botany, ethnomedicinal uses, phytochemistry, pharmacological activities, clinical applications and toxicological evaluations of 11 species of Morinda found in India.

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“…After being the magical antibacterial irrigant over the years, NaOCL is the best choice when the bacterial reduction is required [23, 24]. However, its cytotoxic effects restrict its use in certain biological experiences; efforts have been made to find alternatives [25, 26]. The traditional irrigation approaches are efficient in cleaning root canals coronally, but less effective apically [27].…”

Section: Discussionmentioning

confidence: 99%

The Use of Different Irrigation Techniques to Decrease Bacterial Loads in Healthy and Diabetic Patients with Asymptomatic Apical Periodontitis

Ghoneim

Saber

El-Badry³

et al. 2016

Open Access Maced J Med Sci

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BACKGROUND:Diabetes mellitus is a multisystem disease which weakens the human’s immunity. Subsequently, it worsens the sequelae of apical periodontitis by raising a fierce bacterial trait due to the impaired host response.AIM:This study aimed to estimate bacterial reduction after using different irrigation techniques in systemically healthy and diabetic patients with asymptomatic apical periodontitis.MATERIAL AND METHODS:Enterococcus faecalis, Peptostreptococcus micros, and Fusobacterium necleatum bacteria were chosen, as they are the most common and prevailing strains found in periodontitis. Bacterial samples were retrieved from necrotic root canals of systemically healthy and diabetic patients, before and after endodontic cleaning and shaping by using two different irrigation techniques; the conventional one and the EndoVac system. Quantitive polymerase chain reaction (qPCR) was utilised to detect the reduction in the bacterial count.RESULTS:The EndoVac irrigation system was effective in reducing bacteria, especially Peptostreptococcus micros in the diabetic group when compared to conventional irrigation technique with a statistically significant difference.CONCLUSION:The EndoVac can be considered as a promising tool in combination with irrigant solution to defeat the bacterial colonies living in the root canal system. Additional studies ought to be done to improve the means of bacterial clearance mainly in immune-compromised individuals.

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Comparative evaluation of antimicrobial effect of herbal root canal irrigants (Morinda citrifolia, Azadirachta indica, Aloe vera) with sodium hypochlorite: An in vitro study

Cited by 42 publications

References 10 publications

Properties and Applications of Morinda citrifolia (Noni): A Review

Properties and Applications of Morinda citrifolia (Noni): A Review

Indian Morinda species: A review

The Use of Different Irrigation Techniques to Decrease Bacterial Loads in Healthy and Diabetic Patients with Asymptomatic Apical Periodontitis

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