Comparative evaluation of efficacy and safety of A Unani coded drug UNIM-221 and Metformin in cases of Diabetes mellitus type-II: A preliminary study

Verma, RS; Parveen, Shahana; Rehman, Sohaib Abdul; Khan, Paeenda; Singh, Ravi Shekhar; Afza, S; Akhtar, Jawed; Khan, Asim Ali

doi:10.33545/2616454x.2021.v5.i1a.154

Cited by 2 publications

(3 citation statements)

References 15 publications

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“…Swapping out the basal-bolus. [21][22] In the event of beta cell exhaustion, insulin becomes required. In cases of glucose toxicity, replacement therapy-which aims to replicate the regular release of insulin by the pancreatic beta cells-is required for rescue therapy.…”

Section: Insulinmentioning

confidence: 99%

“…Compared to the short acting forms, the long acting forms have a lower risk of causing hypoglycemia. [22] Insulin analogue…”

Section: Insulinmentioning

confidence: 99%

“…The peaks of action of traditional intermediate-and long-acting insulins, such as NPH insulin, lente insulin, and ultralente insulin, can cause hypoglycemia due to their uneven absorption. [22][23] The new insulin analogues have different pharmacokinetic profiles from regular insulins, and they have varying rates of onset and durations of action. There is currently one long-acting insulin analog, insulin glargine, and two rapid-acting insulin analogs, insulin lispro and insulin aspart.…”

Section: Insulinmentioning

confidence: 99%

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Comparative study of allopathy and ayurveda for treatment of diabetes mellitus

Yogesh N Sonawane,

Megha P Yeole,

Piyush V Wagh

et al. 2024

GSC Biol. Pharm. Sci.

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These days, one of the most prevalent non-communicable diseases is diabetes mellitus. It has an impact on people worldwide of all ages and their families, and it heavily strains national budgets and healthcare systems. In the short term, implementing a comprehensive healthcare management program for individuals with diabetes can result in significant improvements in clinical outcomes and costs. Millions of people throughout the world suffer from diabetes mellitus, a chronic metabolic illness. To avoid complications and enhance the quality of life for those with diabetes, management is crucial. The two main methods used to treat diabetes are Ayurveda, an ancient system of traditional medicine, and Allopathy, a conventional medical system. The purpose of this study is to compare and contrast these two methods for treating diabetes. The study includes a thorough analysis of the research on diabetes treatment in allopathy and ayurveda, as well as clinical studies and expert opinions.

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Section: Insulinmentioning

confidence: 99%

“…Compared to the short acting forms, the long acting forms have a lower risk of causing hypoglycemia. [22] Insulin analogue…”

Section: Insulinmentioning

confidence: 99%

Section: Insulinmentioning

confidence: 99%

See 1 more Smart Citation

Comparative study of allopathy and ayurveda for treatment of diabetes mellitus

Yogesh N Sonawane,

Megha P Yeole,

Piyush V Wagh

et al. 2024

GSC Biol. Pharm. Sci.

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Antidiabetic Properties of Nymphaea Species (Water Lilies): A Review

Prodhan

Mridu

2023

NPJ

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Diabetes mellitus is a highly prevalent metabolic disease specified by increased blood glucose and impaired insulin function. Various antidiabetic drugs are currently being used, but plant sources of antidiabetic agents are of recent scientific interest as they possess multitarget effects and the most negligible side effects. Nymphaea species (water lilies) have long been traditionally taken as food and antidiabetic agents. Growing research evidence suggests that different Nymphaea species exhibit antidiabetic activity. Therefore, we took an endeavor to summarize the available scientific literature on the antidiabetic activity of the genus Nymphaea. We extensively searched in three search engines and selected 27 in vivo, 9 in vitro, and 4 in silico studies regarding antidiabetic properties of 7 Nymphaea species named Nymphaea stellata, Nymphaea pubescens, Nymphaea lotus, Nymphaea alba, Nymphaea nouchali, Nymphaea rubra, and Nymphaea odorata. All these studies coincided with the conclusion that the Nymphaea species have effective antidiabetic properties and safety. Therefore, Nymphaea species are potential candidates for evidence-based complementary and alternative medicine and integrative medicine. The species have been found to show antidiabetic properties by antihyperglycemic, antihyperlipidemic, pancreatic β-cell-regenerating, insulin secretion and sensitivity promoting, glucose uptake and metabolizing protein-expressing, intestinal glucose metabolizing enzyme inhibiting, hepatoprotective, cardiovascular protective, nephroprotective, antioxidant, and anti-inflammatory activity. A variety of antidiabetic compounds have been identified in the 7 Nymphaea species, which can be responsible for the antidiabetic activity exerted by diverse mechanisms. Future studies should be conducted on other Nymphaea species and different plant parts and diabetic parameters to investigate their antidiabetic activity and responsible phytochemical contents.

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Comparative evaluation of efficacy and safety of A Unani coded drug UNIM-221 and Metformin in cases of Diabetes mellitus type-II: A preliminary study

Cited by 2 publications

References 15 publications

Comparative study of allopathy and ayurveda for treatment of diabetes mellitus

Comparative study of allopathy and ayurveda for treatment of diabetes mellitus

Antidiabetic Properties of Nymphaea Species (Water Lilies): A Review

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