Comparative evaluation of efficacy and latency of twin mix vs 2% lignocaine HCL with 1:80000 epinephrine in surgical removal of impacted mandibular third molar

Sahu, Swati; Patley, Abhishek; Kharsan, Vinay; Madan, Rashmi; Manjula, VD; Tiwari, Rahul Vc

doi:10.4103/jfmpc.jfmpc_998_19

Cited by 11 publications

(2 citation statements)

References 13 publications

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“…[ 5 ] Nonetheless, additional research on the effectiveness of tramadol in oral surgery is still required. [ 6 ]…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research

Khan,

Gopalakrishnan,

Busani

et al. 2024

Journal of Pharmacy and Bioallied Sciences

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Aim: This study was intended to assess and relate the clinical anesthetic effectiveness of tramadol hydrochloride and lidocaine. Methodology: A clinical randomized split-mouth study was piloted among 40 patients who were otherwise healthy but needed to have their maxillary first premolars extracted bilaterally for orthodontic reasons were considered in the research. In each subject on one side (quadrant) of the arch 1.8 milliliters of lidocaine was given and on other side of the arch 1.8 milliliters of tramadol was given. On the basis of a list that was prepared by a computer, the randomization was done and the sides (quadrant) of the arches were decided for all the subjects, and the injections were given as local infiltration. Results: Lidocaine was found to be statistically more effective for overall anesthesia duration, despite the fact that there was no significant variance between the two drugs at the time when anesthetic effect began to take effect. Tramadol was found to be statistically more efficient than lidocaine when compared to the anesthetic activity at the 5th minute before extraction. Tramadol was found to be statistically more successful than lidocaine for both the patient’s degree of satisfaction and the rate at which wounds healed. Conclusion: Based on the findings of this research, it appears that tramadol and epinephrine could be used as a substitute to conventional local anesthetics during extractions of maxillary first premolar teeth during oral-maxillofacial surgery.

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“…[ 5 ] Nonetheless, additional research on the effectiveness of tramadol in oral surgery is still required. [ 6 ]…”

Section: Introductionmentioning

confidence: 99%

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research

Khan,

Gopalakrishnan,

Busani

et al. 2024

Journal of Pharmacy and Bioallied Sciences

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“…The combination of dexamethasone with 2% lignocaine and 4% articaine are popularised as Twin Mix and Modi ied Twin Mix respectively. The intraspace injection of this mixture not only helps in increasing the postoperative comfort and quality of life but also increases the latency, depth and duration of anesthesia intra-operatively (Bhargava et al, 2015(Bhargava et al, , 2016Kharsan et al, 2020). Bhargava et al proposed the mechanism of action of these mixtures in 2018.…”

Section: Introductionmentioning

confidence: 99%

Comparison of twin mix and revamped twin mix in mandibular third molar surgery - A randomised controlled double blinded study

Albert¹,

Gouthaman²,

Muthusekhar³

2020

ijrps

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Mandibular third molar surgery is one of the most common minor oral surgical procedures performed by oral and maxillofacial surgeons. It is vital to provide the most comfortable postoperative phase to the patient and for this reason dexamethasone, a corticosteroid, is popularly used in various routes. The intraspace injection of dexamethasone mixed with 2% lignocaine and 4% articaine named, Twin Mix and Modified Twin Mix respectively is gaining increasing popularity. 0.5% Centbucridine is a safe alternative to 2% lignocaine with more cardio stable properties. In this study we aimed to evaluate the comparability of Twin Mix(TM) and Revamped Twin Mix(RTM) (mixture of dexamethasone and centbucridine) with respect to its anesthetic properties and its effectiveness in managing postoperative sequelae following mandibular third molar surgery. For this, a randomised controlled double blinded study was conducted among patients reporting to the Out Patient Department of a dental college. The sample size of the population studied was 32, 16 in Group A (RTM) and 16 in Group B (TM). The primary outcomes measured were facial swelling and mouth opening on postoperative day(POD) 1, 3 and 7. The secondary outcomes were VAS score during the surgical procedure, duration and latency of anesthesia. The data were analysed descriptively and using Student’s t Test. Representations were given in graphical and tabular forms. The mean postoperative mouth opening and facial swelling on POD 1, 3 and 7 were comparable and did not show any statistically significant difference. Similarly, the VAS score during procedure, latency and duration of anesthesia were comparable with no statistically significant difference. In conclusion, RTM can be used as an alternative to TM due to its comparable properties.

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Efficacy of different dexamethasone routes and doses in reducing the postoperative sequelae of impacted mandibular third-molar extraction

Almadhoon¹,

Hamdallah²,

Eida³

et al. 2022

The Journal of the American Dental Association

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Comparative evaluation of efficacy and latency of twin mix vs 2% lignocaine HCL with 1:80000 epinephrine in surgical removal of impacted mandibular third molar

Cited by 11 publications

References 13 publications

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research

Assessment of the Efficiency for Anesthesia of Two Agents in Teeth Removal: A Split-Mouth Research

Comparison of twin mix and revamped twin mix in mandibular third molar surgery - A randomised controlled double blinded study

Efficacy of different dexamethasone routes and doses in reducing the postoperative sequelae of impacted mandibular third-molar extraction

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