Comparative evaluation of outcomes amongst different radiosurgery management paradigms for patients with large brain metastasis

Kutuk, Tugce; Zhang, Yanjia; Akdemir, Eyub Yasar; Yarlagadda, Sreenija; Tolakanahalli, Ranjini; Hall, Matthew D.; La Rosa, Alonso; Wieczorek, DJay J.; Lee, Yongsook C.; Press, Robert H.; Appel, Haley; McDermott, Michael W.; Odia, Yazmin; Ahluwalia, Manmeet S.; Gutierrez, Alonso N.; Mehta, Minesh P.; Kotecha, Rupesh

doi:10.1007/s11060-024-04706-2

J Neurooncol

2024

DOI: 10.1007/s11060-024-04706-2

|View full text |Cite

Comparative evaluation of outcomes amongst different radiosurgery management paradigms for patients with large brain metastasis

Tugce Kutuk,

Yanjia Zhang,

Eyub Yasar Akdemir

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

2025

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Preoperative versus postoperative stereotactic radiosurgery for brain metastases: a systematic review and meta-analysis of comparative studies

Maroufi,

Fallahi,

Maroufi

et al. 2025

Neurosurg Rev

View full text Add to dashboard Cite

Preoperative versus postoperative stereotactic radiosurgery for brain metastases: a systematic review and meta-analysis of comparative studies

Maroufi,

Fallahi,

Maroufi

et al. 2025

Neurosurg Rev

View full text Add to dashboard Cite

Multidisciplinary management strategies for recurrent brain metastasis after prior radiotherapy: An overview

Kotecha,

La Rosa,

Brown

et al. 2024

Neuro-Oncology

View full text Add to dashboard Cite

As cancer patients with intracranial metastatic disease experience increasingly prolonged survival, the diagnosis and management of recurrent brain metastasis pose significant challenges in clinical practice. Prior to deciding upon a management strategy, it is necessary to ascertain whether patients have recurrent/progressive disease vs adverse radiation effect, classify the recurrence as local or distant in the brain, evaluate the extent of intracranial disease (size, number and location of lesions, and brain metastasis velocity), the status of extracranial disease, and enumerate the interval from the last intracranially directed intervention to disease recurrence. A spectrum of salvage local treatment options includes surgery (resection and laser interstitial thermal therapy [LITT]) with or without adjuvant radiotherapy in the forms of external beam radiotherapy, intraoperative radiotherapy, or brachytherapy. Nonoperative salvage local treatments also range from single fraction and fractionated stereotactic radiosurgery (SRS/FSRS) to whole brain radiation therapy (WBRT). Optimal integration of systemic therapies, preferably with central nervous system (CNS) activity, may also require reinterrogation of brain metastasis tissue to identify actionable molecular alterations specific to intracranial progressive disease. Ultimately, the selection of the appropriate management approach necessitates a sophisticated understanding of patient, tumor, and prior treatment-related factors and is often multimodal; hence, interdisciplinary evaluation for such patients is indispensable.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Comparative evaluation of outcomes amongst different radiosurgery management paradigms for patients with large brain metastasis

Cited by 2 publications

References 49 publications

Preoperative versus postoperative stereotactic radiosurgery for brain metastases: a systematic review and meta-analysis of comparative studies

Preoperative versus postoperative stereotactic radiosurgery for brain metastases: a systematic review and meta-analysis of comparative studies

Multidisciplinary management strategies for recurrent brain metastasis after prior radiotherapy: An overview

Contact Info

Product

Resources

About