Comparative Evaluation of Oxygen‐Ozone Therapy and Combined Use of Oxygen‐Ozone Therapy with Percutaneous Intradiscal Radiofrequency Thermocoagulation for the Treatment of Lumbar Disc Herniation

Gautam, Sujeet; Rastogi, V.; Jain, Ankur; Singh, Anurag

doi:10.1111/j.1533-2500.2010.00409.x

Cited by 35 publications

(38 citation statements)

References 21 publications

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“…Patients who do not respond to conservative therapies, present neurological findings, or have complaints related to compression are candidates for surgery. The rate of recurrence after surgery in these patients is as high as 40% . Therefore, nonsurgical treatments are needed before surgery.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

et al. 2019

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Aim Paravertebral ozone injection is a new treatment method described in the literature for low back pain. The aim of this study was to compare the pre‐ and post‐treatment pain scores of patients undergoing paravertebral ozone/oxygen (O3/O2) injections for low back pain. Methods From September 2018 to December 2018, 122 patients who underwent paravertebral ozone injections due to low back pain were examined retrospectively; 62 patients who met the study criteria were included. The patients were injected with 15 µg/mL (50 mL) O3/O2 gas in the paravertebral space. The subjects were treated every 7 days for 6 total session. The VAS and Oswestry Disability Index (ODI) scores were assessed before treatment and after treatment (first and third months). The patients’ body mass indexes (BMIs) were measured before the injections. Results There were 12 male patients and 50 female patients. The mean age was 51.9 (range 25 to 71) years. The mean duration of pain was 9.1 (3 to 24) months. Significant improvements were observed in the statistical comparison of VAS and ODI scores between the pre‐injection and first month controls (P < 0.000). There was no significant difference in the statistical comparison of VAS and ODI scores between the first and third months (P < 0.05). There was no statistically significant difference between BMI and pain scores (P > 0.213). Conclusion Paravertebral O3/O2 gas is a reliable and effective treatment for the treatment of lumbar disc herniation, radicular pain, and mechanical back pain due to low back pain.

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Section: Introductionmentioning

confidence: 99%

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

et al. 2019

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“…Both RCTs using OOT showed improvement in pain and disability at 6 months. Gautam et al [23] demonstrated benefit of OOT alone with perhaps a cumulative effect of PIRFT when used as an adjunct. Likewise, Li et al showed additional benefit with psoas compartment block in combination with OOT.…”

Section: Discussionmentioning

confidence: 97%

“…A study by Guatam et al in 2011 aimed to evaluate the efficacy of oxygen-ozone therapy (OOT) alone and when used in conjunction with IDRFT [23]. This study demonstrated promising results for patients with pain secondary to contained lumbar disc herniation.…”

Section: Ablative Proceduresmentioning

confidence: 94%

“…Additional studies have evaluated the effectiveness of Intradiscal ablative procedures including electrothermal [21][22][23] and radiofrequency thermocoagulation [24 •• , 25 •• , [26][27][28], anuloplasty [29], biacuplasty [30][31][32], and coblation [33] in reducing discogenic LBP. Of these trials, 6 were randomized controlled trials.…”

Section: Ablative Proceduresmentioning

confidence: 99%

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A Systematic Review of Available Treatments for Discogenic Low Back Pain

Lucas

Stewart

Mattie

et al. 2016

Curr Phys Med Rehabil Rep

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Discogenic pain is a known cause of low back pain (LBP). There are several proposed minimally invasive treatments in the literature including: percutaneous laser disc decompression, multiple radiofrequency thermocoagulation/ablative techniques, and intradiscal injection of varying medications. The body of literature suffers significantly from patient heterogeneity due to a lack of stringent inclusion criteria. Additional concerns in the literature include random follow-up times, variability in reported results, and non-reproducibility of findings. Collectively, these flaws significantly limit the conclusions that can be made regarding treating those with suspected discogenic pain. Despite this, the article will review the published literature to date on the interventional procedures for patients with suspected discogenic LBP.

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“…Furthermore, medical ozone treatment of herniated disk exerts analgesic and anti-inflammatory effects. [3] In this paper, we present a case of pneumocephalus in a patient who received medical ozone treatment after failed back surgery and review the related literature.…”

Section: Severe Headache Following Ozone Therapy: Pneumocephalusmentioning

confidence: 99%

Severe headache following ozone therapy: pneumocephalus

Toman

Özdemir²,

Kiraz³

et al. 2016

Agri

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ÖzetPnömosefali kranial kavitede havanın olmasıdır. Pnömosefali epidural anestezi veya epidural steroid enjeksiyonu sırasında yanlışlıkla duranın delinmesi ile meydana gelebilir. Olgumuz 41 yaşında kadın hasta, lomber disk hernisi tanısı ile opere olmuş fakat şikayetleri devam ediyordu başarısız bel cerrahisi sendromu olduğu düşünüldü. Ameliyathanede sedoanaljezi yapılarak steril koşullarda ve skopi altında RACZ kateteri kaudal bölgeden epidural alana yerleştirildi. İlk olarak Madrid deklarasyonu doğrul-tusunda 20 ug/ml konsantrasyon ve 5 ml hacimde oksijen-ozon karışımı epidural aralığa verildi. Perkütan epidural nöroplasti için 5 dakika sonra 1500 Ünite hiyalüronidaz, %0.25 bupivakain + 80 mg triamsinolon kateterden yapıldı. İşlem sonrası hasta sedyeye alınır iken şiddetli baş ağrısı ve mide bulantısı şikayeti oldu. Hemen bilgisayarlı beyin tomografisi çekildi ve pnömosefali ile uyumlu hava, sağ lateral ventrikül frontal boynuzu, interhemisferik fissür ve süperior serebellar sisternada gözlendi. Hasta Trendelenburg pozisyonuna getirildi ve intravenöz sıvı verildi. Tedavi olarak analjezikler verildi ve yatak istirahati tavsiye edildi. Hasta ikinci gününde taburcu edildi. Baş ağrısı ve şikayetleri bir hafta içinde kayboldu. Bu yazıda başarısız bel cerrahisi sonrası, medikal ozon tedavisinin bir komplikasyonu olarak gelişen pnömosefaliyi literatür bilgileri ışığında tartışmaya çalıştık.Anahtar sözcükler: Epidural anestezi; başağrısı; ozon-oksijen teadvisi; pnömosefali. SummaryPneumocephalus is defined as air in the cranial cavity. Pneumocephalus can result from inadvertent dural puncture during lumbar epidural anesthesia or epidural steroid injection. Presently described is case of 41-year-old woman who had undergone lumbar disc hernia operation but due to ongoing complaints, was diagnosed as having failed back surgery syndrome. Percutaneous epidural neuroplasty was performed. In the operating room, under sterile conditions and under sedoanalgesia, Racz catheter was inserted in caudal area and guided to epidural area with scope. In accordance with Madrid Declaration, 20 ug/mL concentration and 5 mL volume oxygen-ozone mixture was injected. After waiting 5 minutes, 0.25% bupivacaine + 80 mg triamcinolone + 1500 units hyaluronidase was administered through the catheter. After epidural neuroplasty procedure, when patient was taken to gurney, she complained of severe headache and nausea. Computed tomography scans of head were done immediately, and consistent with pneumocephalus, air was observed in right lateral ventricle frontal horn, interhemispheric fissure, and superior cerebellar cistern. Patient was placed in Trendelenburg position and intravenous fluid was replaced. Analgesics and bed rest were recommended as treatment. Patient was discharged from hospital on the second day. Within a week, headache pain and other complaints had resolved. In this article, the case of a failed back surgery patient who was postoperatively treated with medical ozone and experienced complication of pneumocephalus is discussed in co...

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Comparative Evaluation of Oxygen‐Ozone Therapy and Combined Use of Oxygen‐Ozone Therapy with Percutaneous Intradiscal Radiofrequency Thermocoagulation for the Treatment of Lumbar Disc Herniation

Abstract: Ozone-PIRFT is more efficacious than ozone alone in reducing pain scores, analgesic consumption, improving functional outcome, and satisfaction of patients with contained lumbar disc herniation.

Cited by 35 publications

References 21 publications

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

The Effect of Paravertebral Ozone Injection in the Treatment of Low Back Pain

A Systematic Review of Available Treatments for Discogenic Low Back Pain

Severe headache following ozone therapy: pneumocephalus

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