Comparative Evaluation of Push-out bond Strength of Three Endodontic Sealers with and without Amoxicillin-An Invitro Study

Abstract

Introduction: The purpose of this study was to evaluate the sealing ability of three different root canal sealers with and without amoxicillin, using a push-out bond strength test. Material and Methods:Sixty single-rooted extracted human teeth were used for this study. Each tooth was instrumented and irrigated with 5.25% Sodium hypochlorite (NaOCl) and 17% EDTA. The teeth were then divided into six test groups: Gutta percha (GP)/AH Plus (Dentsply, Germany), GP/AH Plus with 10% amoxicillin (TEVA Pharmaceuticals Sellersville, PA), GP/Pulp Canal Sealer EWT (Extended Working Time, SybronEndo Orange, CA), GP/Pulp Canal Sealer EWT with amoxicillin, GP/Apexit Plus, GP/Apexit Plus (Vivadent, Tulsa, US) with amoxicillin. After the sealer was set, the entire root was sectioned into 1 mm thick slices. A push-out bond strength test was performed by using a universal testing machine. The Student's t-test was used to compare the sealer bond strength within the specific sealer test groups and within each sealer at apical, middle and coronal root levels.Results: There was no significant difference between the groups within each sealer (p>0.05) with or without amoxicillin at the same root level. Conclusion:This study demonstrated that the addition of 10% by weight of amoxicillin does not significantly (p> 0.05) change the overall push-out bond strength of three endodontic sealers when compared at the apical, middle, and coronal tooth level.

Time-Dependent Effect of Chitosan Nanoparticles as Final Irrigation on the Apical Sealing Ability and Push-Out Bond Strength of Root Canal Obturation

“…The amino group in chitosan can be protonated, which leads to the withdrawal of other molecules for adsorption into the root canal dentin, resulting in entering more in depth into the dentinal tubules [ 14 ]. On the contrary, the epoxy resin is hydrophobic; hence, the hydrophilic nature of chitosan is able to increase the wetting ability of the sealer material to the root canal wall, which has an irregular surface due to the opening of the dentinal tubules after instrumentation and irrigation [ 29 , 33 ]. Furthermore, nanosized chitosan particle size can amplify the flow of irrigation solution into the dentinal tubules inducing smear layer removal increase; as a result, adequate bond strength can be achieved between the obturation material and root canal wall [ 4 , 8 ].…”

“…In addition, the smear layer is more challenging to be eliminated in the apical part of the root canal since the diameter of the root canal is getting narrower in the apical third [ 23 ]. Therefore, the longer application time of irrigation solution is more effective in removing the smear layer in the apical third of root canal, which in turns, greater sealing ability and bond strength accomplished [ 33 ].…”

A comparative evaluation of the sealing ability of two calcium silicate based sealers and a resin epoxy-based sealer through scanning electron microscopy and bond strength

“…Each root was embedded in a centralized manner in acrylic resin using a transparent plastic mold (diameter 10 mm, length 16mm) so that the tooth surface flushes with the upper acrylic surface. After setting of the acrylic resin, coronal, middle and apical thirds were defined and a section of 1mm thickness was cut from the center of each third using water-cooled precision microsaw 9 . Test was conducted using computer-controlled universal testing machine (Instron universal testing machine model 3354 instron instruments England) with a load cell of 5-KN.…”

“…A plunger with diameter of (0.9mm or 0.7mm or 0.5mm) acted as a force probe to apply a push out load at a crosshead speed of 0.5mm/min in an apical coronal direction. The selected diameter of the plunger was chosen so that it only contacts the filling to displace it downwards 9 . The maximum failure load was recorded in newtons (N) and was used to calculate the push-out bond strength in mega pascals (Mpa) according to the following formula.…”

Comparative Evaluation of Anti Microbial effects of Triple Antibiotic Paste and Amox and its derivatives against E. faecalis: An in vitro study

“…Amoxicillin is absorbed more rapidly than and provides a higher and more continuous serum level. Augmentin is recommended as “fall-back” antibiotics when infections do not respond to traditional dental antibiotics ( 8 , 10 ).…”