Comparative evaluation of the efficacy of fluoride varnish and casein phosphopeptide – Amorphous calcium phosphate in reducing Streptococcus mutans counts in dental plaque of children: An in vivo study

Chandak, Shweta; Bhondey, Ashish; Bhardwaj, Amit; Pimpale, Jitesh; Chandwani, Manisha

doi:10.4103/2231-0762.192936

Cited by 16 publications

(10 citation statements)

References 25 publications

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“…In Table (1), the results showed there were no significant difference at baseline and demineralization between and within groups due to the use the same protocol of demineralization for all groups, while in demineralization there was a high significant difference between and (21,22) .…”

Section: Discussionmentioning

confidence: 97%

Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Hardness After a pH Challenge

Al-Ani¹,

Al-Naimi²

2021

RDENTJ

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Aims:The aim of this study was to evaluate the effect of CPP−ACP, raw fresh buffalo milk and cow milk on the microhardness of artificial initial caries lesions. Materials and Methods: 100 sound maxillary first premolars were collected and randomly divided into four groups, the teeth in all groups were subjected to pH cycling procedure then treated with: Group1: n (25) deionized water, group2: n (25) CPP−ACP tooth mousse, group3: n (25) fresh raw cow milk, group4: n (25) fresh raw buffalo milk. Enamel surface was assessed by Vickers microhardness test device at a baseline and after demineralization and after remineralization. Results: In all groups, there were high statistically significant reduction of surface microhardness after demineralization. There was high statistically significant increase in surface microhardness in all groups except deionized water after remineralization, the highest remineralization effect was found in CPP−ACP tooth mousse group followed by the milk groups that showed encouraging results with fresh raw buffalo milk having superior results then fresh raw cow milk. Conclusions: CPP−ACP tooth mousse, raw fresh buffalo milk and cow milk were effective remineralizing agents which were reflected by increasing the surface microhardness of artificial initial caries lesion, but with different abilities, CPP−ACP tooth mousse was the best followed by buffalo milk then cow milk.

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Section: Discussionmentioning

confidence: 97%

Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Hardness After a pH Challenge

Al-Ani¹,

Al-Naimi²

2021

RDENTJ

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“…(16) MI varnish containing CPP-ACP is a more stable and durable varnish and was found to be more effective in the reduction of Candida albicans count when compared with other fluoride varnishes Clinpro XT varnish, Fluor protector varnish, which was seen in compliance with the study conducted by Vinola Duraisamy et al (2015) (17) and Shweta Chandak et al (2016). (18) According to Salman et al (2019) (19) and Ankita Maurya et al (2020) (20) fluoride varnish containing CPP-ACP were found to have an increased acid resistance thus preventing the incidence of dental caries. This was in agreement with the current study.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

JR¹,

Gupta²,

Gambhir³

et al. 2022

Journal of Pharmaceutical Negative Results

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PURPOSE: Candida albicans one of the commensal organisms in the oral cavity, causes fermentation of the dietary carbohydrates leading to the formation of organic acids, which contributes to the development of dental caries. The aim of the study was to evaluate and compare the efficacy of 3 different fluoride varnishes against Candida albicans in the prevention of dental caries before and immediately after fluoride varnish application and also over a period of 1 week, 1 month and 3 months. METHODOLOGY: A sample size of 60 children’s aged between 6-12 years were randomly selected by block randomization and divided into 3 groups: Group 1 MI Varnish, Group 2 Clinpro XT varnish and Group 3 Flour Protector varnish. Unstimulated saliva samples were collected before and after the application of fluoride varnishes (collected immediately after application, after 1 week, 1 month and 3 months) and were sent for microbiological analysis. The pH of the samples were evaluated by Indikrom paper strips. The results obtained were statistically analysed by mean, standard deviation and One way ANOVA. RESULTS: MI varnish showed a significant drop in Candida albicans followed by Clinpro XT varnish and Fluor Protector Varnish whereas no significant difference were seen in pH. CONCLUSION: The results of the study shows that MI Varnish, Clinpro XT Varnish and Fluor Protector Varnish have antifungal effect on Candida albicans. MI Varnish showed its more profound effect.

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“…CPP-ACP is also believed to have an antibacterial and buffering effect on plaque and interfere with the growth and adhesion of Streptococcus mutans species [28]. In a clinical study, Shweta Chandak et al (2016) examined the impact of CPP-ACP alone and in combination with fluoride on the amount of Streptococcus mutans in children's dental plaque and concluded that both groups significantly reduced this microorganism, of which the rate is higher in the combination of these two substances [29].…”

Section: Introductionmentioning

confidence: 99%

Comparative Evaluation of Antibacterial Effect of Propolis and Aloe Vera, Xylitol, and Cpp-Acp Gels on Streptococcus mutans and Lactobacillus in Vitro

Hajiahmadi

Faghri

Salehi

et al. 2021

International Journal of Dentistry

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Introduction. Early childhood caries is a kind of caries occurring in deciduous teeth. Bacteria are among the main factors. Antibacterial agents such as fluoride are used in both prevention and treatment, but their application in children faces limitations such as fluorosis. Therefore, novel methods of caries prevention among the children are mainly focused on the use of fluoride-free active ingredients. In this comparative study, antibacterial effects of gels containing propolis and aloe vera, fluoride, xylitol, and CPP-ACP were investigated. Methods. This is an in vitro study. By plate well technique, plates containing gels were created in the culture medium of Streptococcus mutans and Lactobacillus, and their antibacterial impacts were evaluated by measuring the inhibition zone after 24, 48, and 72 hours. Then, different concentrations of each gel were evaluated in the same way for the antibacterial properties. For each sample, this process was iterated 3 times, where the average was declared as the final number. The collected data were entered in SPSS 24. Results. In both bacteria, propolis gel and aloe vera had the highest zone of inhibition, followed by fluoride and xylitol in the second and third places, respectively. Different concentrations of gels are significantly different in terms of antimicrobial effect (P value ≤ 0/05). The antimicrobial effect of propolis and aloe vera gel was kept up to the concentration of 1 / 16 . As the bacterial and gel contact time is prolonged, the antibacterial effect of different gels increases, but the difference is not statistically significant (P value = 0.109). CPP-ACP gel had no antimicrobial effect at any concentration. Conclusion. Propolis and aloe vera gel had a greater antimicrobial effect than other gels, where such effect was observed in low concentrations. CPP-ACP gel had no antimicrobial properties.

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Comparative evaluation of the efficacy of fluoride varnish and casein phosphopeptide – Amorphous calcium phosphate in reducing Streptococcus mutans counts in dental plaque of children: An in vivo study

Cited by 16 publications

References 25 publications

Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Hardness After a pH Challenge

Evaluation of the Effect of Casein Phosphopeptide–Amorphous Calcium Phosphate Mousse versus Natural Raw Fresh Milk on Enamel Hardness After a pH Challenge

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

Comparative Evaluation of Antibacterial Effect of Propolis and Aloe Vera, Xylitol, and Cpp-Acp Gels on Streptococcus mutans and Lactobacillus in Vitro

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