Comparative genome analysis of Streptococcus strains to identify virulent genes causing neonatal meningitis

Isolation, characterization, and experimental infection of Streptococcus gallolyticus subspecies pasteurianus from commercial turkeys with acute septicemia: a pilot study

“…In turkeys, SG has been associated with respiratory diseases, septicemia, and bacterial endocarditis ( Saumya et al, 2014 ). The pathogenesis of SG in turkeys may involve multiple virulence factors, including a capsule composed of polysaccharides ( Sitthicharoenchai et al, 2022 ), adhesins ( Lichtl-Häfele, 2022 ; Arya et al, 2023 ), hyaluronidase enzyme that can break down hyaluronic acid and a major component of the extracellular matrix ( Suvarna and Mahon, 2022 ), pore-forming hemolysin toxins that can lyse erythrocytes and other host cells ( Zeng et al, 2022 ), biofilm formation that involves the attachment of bacterial cells to a surface and production of an extracellular matrix that encapsulates the cells to protect them from environmental stressors ( Bruggeling, 2023 ), and intracellular survival ( Kumar et al, 2022 ).…”

Unlocking the mysteries of Alzheimer’s disease: Role of single-cell sequencing in uncovering microbial infections

“…Herpes simplex virus (HSV) increased risk o f Alzheimer's disease [5] Porphyromonas gingivalis cause neurodegeneration in mice [4,17] Chlamydia pneumonia increased risk of Alzheimer's disease [19] Spirochetes cause neurodegeneration in mice [20] Streptococcus neurodegeneration in mice [148] Bacteroides fragilis neurotoxic proteins [149] Enterococcus faecalis formation of amyloid beta plaques [29] Escherichia coli contribute to neuroinflammation [64] Human herpesvirus 6A and 7 increased risk of Alzheimer's disease [150] Fungi (Saccharomyces cerevisiae, Malassezia globosa, Malassezia restricta, Penicillium, Phoma) neurodegeneration in mice [22] Candida tropicalis, Candida krusei [22] Aspergillus fumigatus, Cryptococcus neoformans, and Malassezia spp contribute to the development of AD. Further research is required to fully comprehend the relationship between pathogens and AD and to develop new treatments and prevention strategies [4,17,27].…”