Comparative Phytochemical Constituents and Antioxidant Activity of Wild and Cultivated <i>Alepidea amatymbica</i> Eckl &amp; Zeyh

Mangoale, Ramatsobane Maureen; Afolayan, Anthony Jide

doi:10.1155/2020/5808624

Cited by 19 publications

(12 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The wild’s dependency is because it constitutes free resources and no permits are necessary for collection. Also, MPs users perceive cultivated plants as less effective than wild ones (Moeng and Potgieter 2011), and the absence of scientific evidence on the efficacy of cultivated MPs remains a limiting factor (Mangoale and Afolayan 2020 ). Thus, wild habitats are still crucial for the livelihood of the rural community in the region.…”

Section: Resultsmentioning

confidence: 99%

Herbal remedies used by traditional healers to treat haemorrhoids in Tabora region, Tanzania

Kacholi

Amir

2022

Pharmaceutical Biology

View full text Add to dashboard Cite

Context Haemorrhoids are one of the most common gastrointestinal disorders in humans. In Tanzania, particularly in the Tabora region, medicinal plants (MPs) are used by traditional healers (THs) to treat haemorrhoids, but no study has explicitly attempted to compile these treatments. Objective This study documents MPs used by THs of the Tabora region in Tanzania to treat haemorrhoids. Materials and methods A semi-structured questionnaire was used to gather ethnobotanical data from 44 THs on MPs used to treat haemorrhoids, parts used, preparation methods and administration routes. The collected ethnobotanical data were analysed by computing percentage frequencies and relative frequency citations. Results Twenty-six MPs belonging to 19 families and 25 genera, used to manage haemorrhoids, were documented. Fabaceae was the dominant family (four species), whereas shrubs constituted a high proportion (38.46%) of the MPs, and the root was the most (30.3%) utilized plant part. Decoction (38.5%) and topical application (53.8%) were the most preferred preparation and administration techniques. Most MP materials (76.9%) were sourced from the wild. Aloe vera (L.) Burm.f. (Asphodelaceae) (68%), followed by Allium sativum L. (Alliaceae) (66%) and Psidium guajava L. (Myrtaceae) (66%) were the most utilized MPs. Among the recorded MPs, 12 are reported for the first time for the treatment of haemorrhoids. The recorded MPs are believed to possess anti-inflammatory properties that aid in managing inflammation associated with bowel diseases, including haemorrhoids. Conclusions This study has documented valuable MPs used to manage haemorrhoids and provides a basis for further studies to discover efficient and affordable anti-haemorrhoid drugs.

show abstract

Section: Resultsmentioning

confidence: 99%

Herbal remedies used by traditional healers to treat haemorrhoids in Tabora region, Tanzania

Kacholi

Amir

2022

Pharmaceutical Biology

View full text Add to dashboard Cite

show abstract

“…In albumin denaturation assay, the denaturation is induced by heat treatment. The denaturation of proteins is well documented and is caused by an inflammation process, mostly in conditions like arthritis [42]. Inflammation is a normal biological response of the cells to injury but could also be detrimental to the cell when it is provoked at other instances.…”

Section: Discussionmentioning

confidence: 99%

Assessment of In Vitro Antioxidant and Anti-Inflammatory Potentials of Methanol Extract of Chrysophyllum albidum Cotyledon

Dare

Elvis

2020

PAJOLS

View full text Add to dashboard Cite

Background: This study was aimed at analysing the phytochemicals in Chrysophyllum albidum cotyledon extract and their in vitro antioxidant and anti-inflammatory effects. Methods: The Chrysophyllum albidum cotyledon methanol extract (CCME) was phytochemically screened, and flavonoids and phenol contents, antioxidant and anti-inflammatory assays were carried out on the extract using standard procedures. Results: Phytochemicals analysis revealed the presence of steroids, tannins, flavonoid, saponin, triterpenes and xanthoproteins. The phenolic concentration, total flavonoids concentration and sugar concentration were found to be 26.720.048 μg of Tannic Acid Equivalent (TAE /mg, 23.121.92 μg of Rutin Equivalent (RTE)/mg (10.491.12 μg of Quercetin Equivalent (QE)/mg) and 778.3812.82 μg of glucose/ml respectively. The extract demonstrated significant (P<0.05) inhibitory effect compared with the standards as potent antioxidant with DPPH IC50 of 550.52 ± 82.83 μg/ml, lipid peroxidation (45.85 % – 65.85 %), Ferric reducing power showed linear correlation to the standard and the anti-inflammatory potential with (22.06 % – 26.37 %) percentage protection of the human red blood membrane stability and the percentage inhibition of denaturation of albumin (3.42 % – 7.32 %). Conclusion: The study showed that C. albidum cotyledon methanol extract is a potent antioxidant and anti-inflammatory agent to oxidative stress and pathological disease caused by reactive species.

show abstract

“…The phytochemical constituents greatly differed among the tested solvents in both wild stem extract and in vitro callus extract. This is a sign of solvents varied extracting abilities for phytochemicals [24].…”

Section: Screening and Qualitative Comparison Of Phytochemicalsmentioning

confidence: 99%

Comparative Studies of Phytochemical and Antioxidant Activity of in Vivo Plant and in Vitro Callus Extract of Cardiospermum Halicacabum L.

Thaniarasu

Logeshwari

2021

Asian J Pharm Clin Res

View full text Add to dashboard Cite

Objective: The present investigation focuses on the use of Cardiospermum halicacabum L. in their phytochemical and biological activities. Methods: In this study, in vivo stem and in vitro callus ethanolic extracts of C. halicacabum were tested for their phytochemical attributes by qualitative method, Fourier transform infrared (FTIR), antioxidant, antibacterial, and bioactive compound properties. The bactericidal activity of the in vivo stem and in vitro callus extract has been evaluated in both Gram+ve and Gram-ve microorganisms using the disk diffusion method. Results: The highest frequency (78%) of well developed, dark green organogenic callus was induced from stem explant on Murashige and Skoog (MS) medium supplemented with 0.7 mg/l 2,4-Dichlorophenoxyacetic acid (2, 4-D) and 0.5 mg/l benzyl adenine (BA). The results of FTIR spectra confirmed the presence of functional groups in wild stem and in vitro callus extract of C. halicacabum with various peaks. The total phenolic content in ethanolic extract of in vivo plant and in vitro callus was 80.46 mg gallic acid equivalent (GAE)/g dry weight and 76.4 mg GAE/g dry weight, respectively. The highest percentage of tannins was measured at 78.03 in wild stem ethanol extracts followed by 75.22 in callus extract. The antioxidant activity of 2,2-diphenyl-2- picrylhydrazyl (DPPH) ethanol extract was found to be 206.54 μg/ml. IC50 values of the stem extracts of C. halicacabum are 306 μg/ml and 286 μg/ml in callus extract, respectively. Antibacterial activity of the ethanol extract was higher for Staphylococcus aureus (S. aureus) with a 17 mm zone of inhibition. Conclusion: The present investigation recommended that the callus ethanolic extract function as a good source of biologically active compounds and natural antioxidants.

show abstract

Comparative Phytochemical Constituents and Antioxidant Activity of Wild and Cultivated Alepidea amatymbica Eckl & Zeyh

Cited by 19 publications

References 39 publications

Herbal remedies used by traditional healers to treat haemorrhoids in Tabora region, Tanzania

Herbal remedies used by traditional healers to treat haemorrhoids in Tabora region, Tanzania

Assessment of In Vitro Antioxidant and Anti-Inflammatory Potentials of Methanol Extract of Chrysophyllum albidum Cotyledon

Comparative Studies of Phytochemical and Antioxidant Activity of in Vivo Plant and in Vitro Callus Extract of Cardiospermum Halicacabum L.

Contact Info

Product

Resources

About