Comparative profiling of phenolic compounds from different plant parts of six Terminalia species by liquid chromatography–tandem mass spectrometry with chemometric analysis

Singh, Awantika; Bajpai, Vikas; Kumar, Sunil; Kumar, Brijesh; Srivastava, Mukesh; Rameshkumar, K. B.

doi:10.1016/j.indcrop.2016.04.048

Cited by 38 publications

(24 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most abundant phenolic compounds in QIG were ellagic acid (28.1 g/kg) and catechin (0.716 g/kg). The highest content of ellagic acid was detected in raspberries ( Flores & Ruiz del Castillo, 2015 ) , pomegranates ( Liu et al., 2017 ) , grapes ( Wei et al., 2017 ) , some other fruits ( Milivojević et al., 2011; Ribeiro, Valentão, Baptista, Seabra, & Andrade, 2007 ) , and other plant parts ( Singh et al., 2016 ) . It was shown that both gallic acid and ellagic acid display cytotoxic activity against human promyelocytic leukemia sensitive cell lines and its drug‐resistant sublines ( Maruszewska & Tarasiuk, 2019 ) .…”

Section: Resultsmentioning

confidence: 99%

Compositional analysis, biological activity, and food protecting ability of ethanolic extract ofQuercus infectoriagall

Başyi̇ği̇t

Sağlam

Köroğlu

et al. 2020

J Food Process Preserv

View full text Add to dashboard Cite

This study was aimed to investigate chemical composition, biological activity, and food protecting ability of Quercus infectoria gall (QIG).The total content of phenolics, flavonoids, and hydrolyzable tannins was evaluated. Ion and fatty acid compositions of QIG were identified by ion chromatography and gas chromatography flow ionization detector (GC‐FID), respectively. Ellagic acid (28,156.85 mg/kg) and catechin (716.21 mg/kg) were predominant. The antioxidant activity of QIG was determined as 2.29, 1.65, 1.52, and 1.98 mmol Trolox equivalent antioxidant capacity (TEAC)/g sample for DPPH, ABTS, FRAP, and CUPRAC analyses, respectively. QIG extract exhibited dose‐dependent inhibition on α‐glucosidase enzyme with an IC50 value of 0.002 mg/ml. QIG displayed antimicrobial activity against selected reference and isolated mixed strains, most notably on Escherichia coli. The addition of QIG extract as a natural preservative to pasteurized cow’s milk resulted in lower total bacterial count (TBC), total yeast‐mold count (TYMC), and higher pH compared to control milk. Practical applications Quercus infectoria gall does not have a common use in the food and pharmaceutical industry. Exploration of the the biological value of Q. infectoria gall or its extracts could pave the way for the development of added value natural food preservatives and functional compounds. The chemical composition of Q. infectoria gall should be characterized and its biological functionality should be demonstrated beforehand. The results indicated that this plant could be considered as natural antidiabetic, antioxidant, and protective agents instead of synthetic materials and ingredients for food, cosmetic, and pharmaceutical applications.

show abstract

Section: Resultsmentioning

confidence: 99%

Compositional analysis, biological activity, and food protecting ability of ethanolic extract ofQuercus infectoriagall

Başyi̇ği̇t

Sağlam

Köroğlu

et al. 2020

J Food Process Preserv

View full text Add to dashboard Cite

show abstract

“…The capillary voltage was 4 kV and the extractor 2 V. Table 1 shows the phenolic compounds and the fragmentation conditions that were studied. The conditions were as determined by Singh et al ( 18 ). …”

Section: Methodsmentioning

confidence: 99%

Inhibition of Enzymatic and Oxidative Process by Phenolic Extracts from Spirulina sp. and Nannochloropsis sp.

Scaglioni¹,

Quadros²,

Paula³

et al. 2018

Food Technol. Biotechnol.

View full text Add to dashboard Cite

SUMMARYThis study investigates the capacity of phenolic extracts from microalgae Nannochloropsis sp. and Spirulina sp. to inhibit enzymes and free radical activities, intending to find an innovative way to slow down food damage. HPLC-UV and LC-MS/MS served to determine and confirm, respectively, the phenolic acid profiles in the soluble methanolic (free phenolic) and ethanolic (conjugated phenolic) fractions, and after hydrolysis (bound phenolic fractions). Different procedures measured the antioxidant activity of the extracts to estimate the minimal concentration for the protective effect, stability and versatility of activity. The ability to inhibit the oxidative process (ABTS and DPPH), α-amylase and peroxidase activities were estimated as specific inhibition (%/(min·μg)) for better comparison between the phenolic sources. The phenolic acid mass fractions in the free phenolic extracts from Spirulina sp. and Nannochloropsis sp. were 628 and 641 μg/g, respectively. Phenolic extract from Nannochloropsis sp. showed the highest value of ABTS inhibition (1.3%/(min·μg)) and highest inhibition of peroxidase activity (0.4%/(min·μg)). The extract from Spirulina sp. was a better inhibitor of α-amylase activity (0.07%/(min·μg)). Therefore, the phenolic extracts from the edible microalgae may be applied in food industry as natural protector against endogenous and exogenous hydrolytic and oxidative processes.

show abstract

“…The fragmentation pathways and their diagnostic fragment ions of vanillic acid, caffeic acid, protocatechuic acid, ferulic acid, catechin, epicatechin, orientin, rutin, kaempferol‐3‐ O ‐rutinoside, isovitexin, quercetin, and kaempferol have been extensively studied by LC–MS/MS . Identification and characterization of phenolics are reported in ethanolic extracts of Phyllanthus species by HPLC‐ESI‐QTOF‐MS/MS in negative ionization mode .…”

Section: Resultsmentioning

confidence: 99%

“…The fragmentation pathways and their diagnostic fragment ions of vanillic acid, caffeic acid, protocatechuic acid, ferulic acid, catechin, epicatechin, orientin, rutin, kaempferol-3-O-rutinoside, isovitexin, quercetin, and kaempferol have been extensively studied by LC-MS/MS [15][16][17] S1A, S1B and S1C (Supporting Information). Metabolite assignments were made by comparing retention time, MS and MS/MS data (accurate mass, isotopic distribution and fragmentation pattern) of the compounds reported in the literature.…”

Section: Tandem Mass Spectrometry Analysis Of Pure Standardsmentioning

confidence: 99%

Structural characterization and quantitative determination of bioactive compounds in ethanolic extracts of Boerhaavia diffusa L. by liquid chromatography with tandem mass spectrometry

Kumar

Singh

et al. 2018

Separation Science Plus

Self Cite

View full text Add to dashboard Cite

Rapid and sensitive liquid chromatography with tandem mass spectrometry methods were developed for structural characterization and quantitative determination of bioactive compounds in Boerhaavia diffusa using high‐performance liquid chromatography with electrospray ionization quadrupole time‐of‐flight tandem mass spectrometry and ultra high performance liquid chromatography with electrospray ionization hybrid triple quadrupole‐linear ion trap tandem mass spectrometry in negative ionization mode. Fifty seven compounds were identified and characterized in ethanolic extracts of root, stem and leaf of B. diffusa. Ten compounds that include characteristic compounds eupalitin‐3‐O‐galactopyranoside, eupalitin, and boeravinone B were successfully separated on an Acquity UPLC BEH™ C18 column (1.7 μm, 2.1 mm × 50 mm) within 6 min. The validation parameters showed satisfactory linearities (R2 ≥ 0.9991), accuracy (limit of detection: 0.01–1.40 ng mL−1 and limit of quantitation: 0.05–4.26 ng mL−1) and precision (% relative standard deviation: 0.25–3.45 for intra‐day, and 0.26–3.25 for inter‐day), stability (% relative standard deviation: 0.16–1.87) and recoveries with relative standard deviation (98.67–104.16, % relative standard deviation: 0.20–4.06). Eupalitin‐3‐O‐galactopyranoside (18530.00 μg g−1) was one of the most abundant among the quantified compounds followed by eupalitin (1258.00 μg g−1) in leaf of Samba district. The developed methods could be effectively used for quality control of B. diffusa due to its accuracy, stability, and repeatability.

show abstract

Comparative profiling of phenolic compounds from different plant parts of six Terminalia species by liquid chromatography–tandem mass spectrometry with chemometric analysis

Cited by 38 publications

References 22 publications

Compositional analysis, biological activity, and food protecting ability of ethanolic extract ofQuercus infectoriagall

Compositional analysis, biological activity, and food protecting ability of ethanolic extract ofQuercus infectoriagall

Inhibition of Enzymatic and Oxidative Process by Phenolic Extracts from Spirulina sp. and Nannochloropsis sp.

Structural characterization and quantitative determination of bioactive compounds in ethanolic extracts of Boerhaavia diffusa L. by liquid chromatography with tandem mass spectrometry

Contact Info

Product

Resources

About