Comparative study of bone repair in mandibular body osteotomy between metallic and absorbable 2.0mm internal fixation systems. Histological and histometric analysis in dogs: a pilot study

Sverzut, Cássio Edvard; Kato, Rogério Bentes; Rosa, Adalberto Luiz; Trivellato, Alexandre Elias; Sverzut, Alexander Tadeu; Silveira, Kennia Moura; Oliveira, Paula Approbato de

doi:10.1016/j.ijom.2012.04.012

Cited by 7 publications

(7 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…To the best of our knowledge, while the effects of different types of factors on postoperative osteosynthesis have been well studied, there have been no reports regarding the relationships among bone healing process, resorbable plate biodegradation, and osteosynthesis at particular time-points 14,15 . Therefore, the aim of the present study was to compare bone healing in mandibular vertical body osteotomy (MVBO) after fixation with a resorbable 2.0mm fixation system in the first and third postoperative months in rabbits.…”

Section: Introductionmentioning

confidence: 99%

Bone healing after biodegradable mini-plate fixation

et al. 2016

View full text Add to dashboard Cite

PURPOSE:To compare bone healing in mandibular vertical body osteotomies (MVBO) after fixation with a resorbable 2.0mm-profile fixation system in the first and third postoperative months in rabbits. METHODS:Twenty hemimandibles of ten rabbits were divided into two groups according to duration of resorbable fixation-one or three months. The MVBOs were performed and one four-hole, resorbable, 2.0mm mini-plate fixation system was used on each side.The computed tomography (CT) scans, scanning electron microscopy (SEM), and histomorphometric outcomes of groups I and II were compared.RESULTS: Significant differences were found between the one-and three-month assessments in terms of newly formed bone ratio values (p<0.05). There was more new bone formation at the third month on both the CT and histomorphometric examinations. A better adaptation of the bone tissues to the resorbable mini-plate and screws was observed on SEM at three months. CONCLUSION:The resorbable mini-plates provided a fixation stable enough to allow immediate oral alimentation and callus formation in both groups.

show abstract

Section: Introductionmentioning

confidence: 99%

Bone healing after biodegradable mini-plate fixation

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Biodegradable poly( l ‐lactic acid) (PLLA) plates and screws have been widely used in craniomaxillofacial surgery, such as condyle fracture and osteotomy fixations . Studies have demonstrated that satisfactory outcomes can be achieved when PLLA plates and screws are used in sagittal split ramus osteotomy and condyle fracture, similar to the conventional titanium system . Although PLLA is biocompatible, there are some complications in the reported cases, such as foreign body reaction (local inflammation and redness), swelling, and fistulation .…”

Section: Introductionmentioning

confidence: 99%

Casein phosphopeptides-vaterite calcium carbonate enhance cytocompatibility and osteoinductivity of poly(l -lactic acid)

Liang

Chen

et al. 2014

Polym. Compos.

View full text Add to dashboard Cite

Although calcium carbonate has been proved to be effective in neutralizing the acid degradation products of poly(L-lactic acid) (PLLA), it has no osteoinductivity. In this study, casein phosphopeptides (CPPs)-containing CaCO 3 vaterite were synthesized by fast precipitation in an aqueous solution of CaCl 2 , Na 2 CO 3 , and 2 mg/ml of CPPs. CaCO 3 -PLLA composite membranes (P-vaterite-CPP) were prepared (CaCO 3 /PLLA 51:2) and exhibited uniform structure and increased hydrophilicity. These composite membranes enhanced hydroxyapatite formation after incubated in simulated body fluid at 37 C for 7 days. The P-vaterite-CPP membranes promoted human bone marrow stromal cells (hBMSCs) proliferation 4 and 7 days after seeding. Scanning electron microscope images of hBMSCs on the composite membranes exhibited a polygonal and unevenly spreading morphology. Immunofluorescent staining of cytoskeleton and focal adhesion showed that hBMSCs had more stress fibers and were more spreading, indicating a good cell adhesion on the CPPs-containing composite membranes. Osteogenesis related genes (alkaline phosphatase, collagen type, osteocalcin, and osteopontin) expressions were significantly higher on the CPPs-containing membranes than those on the CPPs-free membranes (P < 0.05). It can be concluded that the addition of CPPs induces vaterite formation and thus improve cytocompatibility and osteoinductivity of PLLA.

show abstract

“…Em uma sequência de análises prévias in vivo (SVERZUT et al, 2012;SVERZUT et al, 2008) Embora a formação de osso novo pudesse ser vista como uma defesa do corpo contra o parafuso (HIRAI et al, 2001), em nosso estudo a neoformação óssea foi em direção ao parafuso metálico evidenciado pela formação de novo osso em contato próximo ao osso lamelar, com células osteoblásticas e osteocíticas em contato o parafuso metálico não como uma defesa, mas como uma interação corporal. Curiosamente, detectamos células gigantes multinucleadas que absorvem a superfície do parafuso absorvível no período de 18 semanas, principalmente no lado monocortical absorvível e na cortical vestibular a partir de parafusos absorvíveis bicorticais.…”

Section: Resultados Histométricosunclassified

Avaliação histológica e histométrica da interface osso-parafuso entre sistemas de fixação interna 2.0 metálico e absorvível. Estudo experimental em cães

Sehn¹

View full text Add to dashboard Cite

show abstract

Comparative study of bone repair in mandibular body osteotomy between metallic and absorbable 2.0mm internal fixation systems. Histological and histometric analysis in dogs: a pilot study

Cited by 7 publications

References 39 publications

Bone healing after biodegradable mini-plate fixation

Bone healing after biodegradable mini-plate fixation

Casein phosphopeptides-vaterite calcium carbonate enhance cytocompatibility and osteoinductivity of poly(l -lactic acid)

Avaliação histológica e histométrica da interface osso-parafuso entre sistemas de fixação interna 2.0 metálico e absorvível. Estudo experimental em cães

Contact Info

Product

Resources

About