Comparative Study of Different Doses of Clonidine as an Adjuvant With Isobaric Levobupivacaine for Spinal Anesthesia: A Literature Review

Abstract

The need to find the lowest possible effective dose of clonidine to avoid its known side effects such as hypotension, bradycardia and sedation motivated us to design the present study. We compared different doses of clonidine as an adjuvant to intrathecal bupivacaine for spinal anesthesia in patients undergoing cesarean section in order to find the lowest possible effective dose. Spinal anesthesia is a safe, reliable and inexpensive technique, with the advantage of providing surgical anesthesia and prolonged postoperative pain relief, in addition to attenuating autonomic, somatic and endocrine responses to surgical stimulation.