Comparative study of laparoscopic versus conventional open surgical staging procedure for endometrial cancer: Our institutional experience

Shanmugam, Subbiah; Thanikachalam, Rajkiran; Murugan, Arul

doi:10.4103/gmit.gmit_82_19

Cited by 7 publications

(7 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A number of studies reported that outcomes after minimal invasive surgery are at least as good as after open surgery for the treatment of EC (Ghezzi et al 2010 ; Odetto et al 2023 ; Papathemelis et al 2020 ; Shanmugam et al 2020 ; Togami et al 2020 ), or even better (Pedra Nobre et al 2020 ). This is in line with the findings of our study.…”

Section: Discussionmentioning

confidence: 99%

Treatment of endometrial cancer from 2000 to 2020 in Germany: a retrospective population based cohort study

Papathemelis,

Ortmann,

Kohl

et al. 2024

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

Purpose Endometrial cancer (EC) is one of the most common malignancies among women in western countries. This study aimed to assess data on patient treatment in Germany throughout two decades to evaluate the development and effect of surgery, radiation, and chemotherapy. Methods This retrospective registry study included 34,349 EC patients diagnosed between 2000 and 2020. Patients were classified into five risk groups. Overall survival was analyzed by Kaplan–Meier method as well as univariable and multivariable Cox regression to evaluate risk factors and treatment options. Results Over the study period, minimal invasive surgery was used more often compared to open surgery and was associated with better overall survival. Patients with advanced EC were more likely to receive multimodal therapy. Patients with intermediate risk EC had a good prognosis upon surgery, which further improved when radiotherapy was added. High-risk patients showed poorer prognosis but clearly benefited from additional radiotherapy. Survival of elderly high-risk patients with a non-endometrioid histology was improved when chemotherapy was added to surgery and radiotherapy. Conclusion Our study includes a large analysis of data from German clinical cancer registries on the care of endometrial cancer during two decades. We observed an increase of minimal invasive surgery. There is evidence that minimal invasive surgery is not inferior to open surgery. Adjuvant radio- and chemotherapy further improves survival depending on risk group and age.

show abstract

Section: Discussionmentioning

confidence: 99%

Treatment of endometrial cancer from 2000 to 2020 in Germany: a retrospective population based cohort study

Papathemelis,

Ortmann,

Kohl

et al. 2024

J Cancer Res Clin Oncol

View full text Add to dashboard Cite

show abstract

“…Il est recommandé de la réaliser par technique mini-invasive si celle-ci est techniquement possible. Même si la technicité de la laparoscopie paraît plus complexe que la laparotomie avec un risque d’exérèse ganglionnaire moindre, de nombreux articles ont validé la faisabilité et de la sûreté de la laparoscopie dans les curages: il existe moins de complications post-opératoires, la durée de séjour est plus courte et les taux de survie et de récidive sont équivalents à la laparotomie [18] , [19] , [20] , [21] , [22] , [23] . De plus, le curage lombo-aortique doit s’étendre jusqu’à la veine rénale gauche car lorsque la région lombo-aortique est atteinte, il existe un taux non négligeable de métastases au-dessus de l‘artère mésentérique inférieure (77 %) [24] , [25] .…”

Section: Discussionunclassified

Évaluation de l’application des recommandations des cancers de l’endomètre de type 2 : étude rétrospective multicentrique

et al. 2020

View full text Add to dashboard Cite

Introduction Les carcinomes de l’endomètre de type 2 sont des cancers peu fréquents et de mauvais pronostique. Il existe très peu d’étude analysant leur prise en charge. L’objectif de l’étude était d’étudier la prise en charge des carcinomes de type 2 dans nos centres en évaluant l’application des recommandations. Matériel et méthode Il s’agit d’une étude multicentrique rétrospective enregistrant les cancers de l’endomètre de type 2 pris en charge de janvier 2009 à décembre 2019. Les analyses ont été adaptées aux dernières recommandations françaises appliquées par rapport à l’année de prise en charge. Résultats Soixante-quatorze carcinomes de type 2 ont été analysés dans dix centres: 34 carcinosarcomes (45,9 %), 29 carcinomes séreux (39,2 %), neuf carcinomes à cellules claires (12,2 %) et deux carcinomes indifférenciés (2,7 %). Lors de la prise en charge initiale, les recommandations étaient appliquées dans 45,9 % des cas. Le principal motif de non-application des recommandations était la non-réalisation d’une stadification ganglionnaire chirurgicale pour 20 patientes (57,1 %). Lors de la prise en charge adjuvante, les recommandations étaient appliquées dans 37,8 % des cas. Le principal motif de non-application des recommandations était la non-réalisation d’une restadification ganglionnaire chirurgicale ou radiologique pour 25 patientes (67,6 %). Discussion L’applicabilité des recommandations pour la prise en charge des carcinomes de type 2 reste difficile en raison de l’âge élevé et des comorbidités des patientes notamment pour la réalisation d’une stadification chirurgicale ganglionnaire pelvienne et lombo-aortique. L’utilisation de nouvelles techniques de stadification permettrait de mieux sélectionner les indications de curages ganglionnaires.

show abstract

“…[ 41 ] Similar favorable observations of laparoscopic surgery for endometrial cancer were reported from India and Malaysia. [ 42 43 ]…”

Section: Introductionmentioning

confidence: 99%

A Review of Laparoscopic Para-aortic Lymphadenectomy for Early-stage Endometrial Cancer: Extraperitoneal Approach May Have the Advantage over Intraperitoneal Approach

Imai,

Hirooka-Nakama,

Hotta

et al. 2023

Gynecology and Minimally Invasive Therapy

View full text Add to dashboard Cite

The importance of lymphadenectomy, including para-aortic nodes, for the accurate staging of endometrial cancer, is well established. Although the therapeutic role of lymph node resection in endometrial cancer is still under debate, some studies support its usefulness for survival benefit. To predict the necessity of lymphadenectomy, several preoperative scoring systems have been proposed as being effective. For endometrial cancer, there is a trend towards minimally invasive surgery, including para-aortic lymphadenectomy. For para-aortic lymphadenectomy, there are two different approaches: the extraperitoneal approach and the transperitoneal approach. The extraperitoneal approach has advantages over the transperitoneal approach in terms of better access to the left aortic nodes, no interference of the bowel, and possibly better options for obese or elderly patients. However, the extraperitoneal approach may have a longer learning curve than the transperitoneal approach. Robot-assisted extraperitoneal para-aortic lymphadenectomy is feasible and safe and may be suitable for patients irrespective of their baseline characteristics.

show abstract

Comparative study of laparoscopic versus conventional open surgical staging procedure for endometrial cancer: Our institutional experience

Cited by 7 publications

References 11 publications

Treatment of endometrial cancer from 2000 to 2020 in Germany: a retrospective population based cohort study

Treatment of endometrial cancer from 2000 to 2020 in Germany: a retrospective population based cohort study

Évaluation de l’application des recommandations des cancers de l’endomètre de type 2 : étude rétrospective multicentrique

A Review of Laparoscopic Para-aortic Lymphadenectomy for Early-stage Endometrial Cancer: Extraperitoneal Approach May Have the Advantage over Intraperitoneal Approach

Contact Info

Product

Resources

About