COMPARATIVE STUDY OF MATERNAL & FETAL OUTCOME IN PREGNANCIES OF GESTATIONAL AGE 40 COMPLETED WEEKS AND BEYOND

Abstract

OBJECTIVE:To investigate the etiological factors resulting in Vitamin B12 deficiency in patients with sub-acute combined degeneration (SACD) and other neurological manifestation manifestations. METHODS: We undertook a prospective study of 50 patients, all clinically suspected to have Vit B12 deficiency; they were investigated clinically, hematologically, biochemically and radiologically. RESULTS: There was a dominance of males (41of 50) with the majority in the age group of more than 40 years of age. There was no correlation between the socio-economic and dietary status on the one hand and the clinical manifestation on the other. Anti-intrinsic factor antibodies (AIFAB) were positive in 19 of 50 patients (38%) and anti-parietal cell antibodies (APCAB) were positive in 28 of 50(56%) patients. CONCLUSION: We conclude that Pernicious anemia is an important cause of various neurological manifestations including s ACD in the Vitamin B12 deficient population in the age group of more than 40 years, irrespective of the socio-economic and dietary status in the Indian subcontinent. It is supported by the presence of AIFAB ro APCAB in this group.

Postdated pregnancy: its maternal and fetal outcome

“…10,15 In study by Dobariya PV et al, there were 58 (69.05%) patients in age group 20 to 30 years, and in study by Patel N et al, there were 32 (64%) cases in age group 20 to 30 years. 11,12,16,17 Maximum women (68%) were primigravida in this study similarly Mahapatro et al, found maximum (72%) of patients were primigravida. 13,14 Alfirevic and Walkinshaw, Morgreaset et al, found in their study that primiparity was significantly associated with postterm pregnancy.…”

“…Shinge N et al, studied that maximum patients (53.7%) underwent spontaneous vaginal delivery, 9.5% patients required instrumental delivery and 37% patients required caesarean section as mode of delivery. 16,22 The rate of instrumental delivery in this study was 2%, whereas in Mahapatro's study it was found to be 5.72%. 13 In the present study, indication for caesarean section was meconium stained liquor with fetal distress in 8 patients (26%) and failure of induction in 7 cases (21%), which were followed by cephalo-pelvic disproportion in 5 cases (16%), severe oligohydramnios in 6 patient (19%) and non-progress of labour in 5 (15%).…”

Study of maternal and fetal outcome in pregnancy beyond 40 weeks: a prospective observational study at a tertiary institute

“…While in another Indian study maximum patients (53.7%) underwent spontaneous vaginal delivery, 9.5% patients required instrumental delivery and 37% patients underwent caesarean section. 15 Dakshnamurthy et al in their study observed a minimal increase (7%) in the incidence of babies with increased birth weight (>3.6 kg) in the post-dated women at 41 weeks compared to 4% increase among 50 cases of postdated women with labor induction at 40 weeks taken as controls. Kandalgaonkar et al noted that majority (80.2%) of the babies born weighed between 2.5 to 3.5 kg, in present study 61.2% were from birth weight between 2.5 to 3.5 kg.…”

Post dated Pregnancy and its Maternal and Fetal Outcome.

“…Present study shows that among maternal complications PPH was 6% and no complications in 87%. A comparative study done by Dr Vijaykumar et al [7] shows rate of PPH was 3.5% and no complications in 87.5%.…”

“…Postterm pregnancy associated with an increased risk of postnatal mortality and morbidity including meconium aspiratiom syndrom, oligohydramnios, macrosomia, fetalbirth injuries, septisemia, rate of non reassuring fetal heart rate, fetal distress in labour and maternal complication incresed c.s rate, cephalopelvic disproportion, cervical tear, dystocia, post partamhemorrhage [6]. Management protocol for postterm pregnancy is fetal surveillance for prolonged pregnancy, induction of labour, during intrapartum care proper monitoring of labour [7].…”