Comparative study of serum copper, zinc, Cu/Zn ratio in pulmonary tuberculosis patients with normal subjects

Abstract

Introduction: Tuberculosis (TB) is an important global health problem. It has more impact on developing and underdeveloped countries. The impact of tuberculosis can be seen by the fact that in 1993, the world Health Organization (WHO) declared tuberculosis a Global Emergency. WHO estimated that tuberculosis infects about one-third of world's population. Every year, 8 million people contract tuberculosis, of which 95% are in the developing world.

Significance of serum copper zinc ratio in smear negative pulmonary tuberculosis cases in Rohilkhand region

“…Karthik G et al 8 and Mohammad Alizadehet et al 10 also reported the similar findings in their study.…”

“…Cu/Zn ratio serves to be an important indicator to assess the level of oxidative stress in case of infectious disease 4,5 and was found to be significantly higher in the serum of tuberculosis patients in several studies. [6][7][8][9][10] Though various studies has been conducted worldwide regarding the role of serum Cu/Zn ration in active pulmonary tuberculosis but very less studies were done from north Indian population and till date no studies was reported on smear negative pulmonary tuberculosis patients. [11][12][13][14][15][16][17][18][19] Objective of this study is to find diagnostic efficacy of serum Cu/Zn ratio in smear negative pulmonary tuberculosis patients.…”