Comparative Study of the Antibacterial Effect of Mouth Washes and Vernonia amygdalina (del.) on Some Tooth Decay Causing Bacteria

Akinyele, Bamidele Juliet

doi:10.9734/bmrj/2014/6386

Cited by 10 publications

(13 citation statements)

References 15 publications

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“…Several studies carried out on this plant had suggested that it contains different bioactive compounds, including, flavonoids, saponins, alkaloids, tannins, phenolics, terpenes, steroidal glycosides, triterpenoids, and several types of sesquiterpene lactones (Erasto et al, 2006;Farombi and Owoeye, 2011;Kiplimo et al, 2011;Toyang and Verpoorte, 2013;Adedapo et al, 2014;Quasie et al, 2016;Luo et al, 2017). These bioactive compounds made them possess different pharmacological properties like antimicrobial, antimalarial, antithrombotic, antioxidant, anti-diabetic, laxative, hypoglycemic, antihelmintic, anti-inflammatory, cathartic, anticancer, antifertility, anti-fungi, antibacterial, and among others (Igile et al, 1994;Akinpelu, 1999;Iwalokun et al, 2006;Erasto et al, 2007;Gresham et al, 2008;Khalafalla et al, 2009;Ilondu, 2010;Farombi and Owoeye, 2011;Anibijuwon et al, 2012;Ngatu et al, 2012;Adetunji et al, 2013;Atangwho et al, 2013;Akinyele et al, 2014;Ezeadila et al, 2015;Udochukwu et al, 2015;Alara et al, 2017c). The objective of this review paper is to outline and discuss the studies that had been done on the bioactive compounds, phytochemical and pharmacological properties of V. amygdalina.…”

Section: Introductionmentioning

confidence: 99%

PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF Vernonia amygdalina: A REVIEW

Alara¹,

Abdurahman²,

Mudalip³

et al. 2017

JCEIB

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Vernonia amygdalina has been a known food and medicinal plants used in Asia and Africa (West Africa) due to its pharmacological effects (antioxidant, anti-diabetes, antiinflammatory, anticancer, anti-malaria, and among others). The phytochemical studies revealed that this plant is enriched with proteins, fats, fibres, amino acids, minerals, vitamins, and carbohydrates. Many bioactive compounds had been isolated from its extracts. Therefore, this review summarized the overview of the bioactive compounds, phytochemical and pharmacological properties of V. amygdalina as well as its mechanism of action and toxicology.

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Section: Introductionmentioning

confidence: 99%

PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF Vernonia amygdalina: A REVIEW

Alara¹,

Abdurahman²,

Mudalip³

et al. 2017

JCEIB

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“…Bacterial infections caused by multiple antibiotic resistant (MAR) bacteria are a growing threat worldwide [2]. Plants have the major advantage of still being the most effective and cheaper alternative source of drugs [3]. Vernonia amygdalina, a member of the Asteraceae family, is a small ever green shrub that grows in tropical Africa [4].…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Assessment of Crude and Fractionated Extracts of Vernonia amygdalina Leaf against Multiple Antibiotic Resistant Bacteria of Wound Infection

Onifade

Agunloye

2019

AJRIMPS

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This study was conducted to determine the antibacterial effect of crude and fractionated extracts of leaves of Vernonia amygdalina against multiple antibiotic resistant bacteria isolate from wounds. The bacteria isolates obtained are: Staphylococcus aureus, Escherichia coli, Pseudomonas aeuroginosa, Klebsiella pneumoniae, Proteus mirabilis and Streptococcus pyogene; they were confirmed standard microbiological techniques. Extracts were prepared from the leaf of the plant using ethanol, chloroform, cold water and hot water. The antibacterial activities of the crude extracts were assayed using the agar well diffusion methods. Multiple antibiotic resistant of the isolates was confirmed in the six (6) isolates. The phytochemical screening revealed the presence of alkaloids, phenols and saponins. All the extract showed varying degrees of activities depending on the extract concentration and the extract solvent. Generally, ethanol rated best as the extraction solvent which was able to inhibit all isolates except K. pneumoniae and P. mirabilis, and inhibits S. aureus at 50 mg/ml with zones 6.997±0.003. The antibacterial efficacy of the extract increases with a corresponding increase in the extract concentration. The MBC values ranged from 50 - 400 mg/mL for all the extraction solvent, and this is very important for people who depend on the plant for their health care needs. Fra 1, 6, and 10 of the column fractions were able to inhibit with 8.997 ± 0.008 mm, 8.993 ± 0.012 mm and 9.007 ± 0.000 mm respectively. The functional groups are Alkene, alkane group, alkyl halides, N-H bend of amides and Alcohol. The leaf of Vernonia amgydalina can be used as a raw material for the production of new antibiotic to control multiple resistant bacteria.

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“…In addition, there are also lactobasillus organisms that plays a role in the formation of dental caries. [5] Streptococcus plays a role in the early stages of caries by destroying the outer part of the enamel, meanwhile lactobasillus will be taking over the role of deep caries. 4 According to RISKESDAS in 2013, DMF-T scores in Indonesia is 4.6.…”

Section: Introductionmentioning

confidence: 99%

“…The catechins contained in the tea leaves are composed of several compounds: C (catechin), EC (epicatechin), EGC (epigalocatechin), and ECG (epigalocatechin). [5] Catechins contained in tea leaves are bactericidal and bacteriostatic. Catechin works by destroying the cytoplasmic membrane of the bacteria as well as causing protein denaturation.…”

Section: Introductionmentioning

confidence: 99%

“…Catechin works by destroying the cytoplasmic membrane of the bacteria as well as causing protein denaturation. [3,5] In addition, the tea also contains fluor.4,6 Fluor possesses antibacterial and antiplaque effects. [4] The results of Dellon et al's research on the inhibition of black tea, green tea and oolong tea towards the growth of Streptococcus mutans.…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness of Rinsing Black Tea Compared to Green Tea in Decreasing Oral Bacterial Counts as an Alternative of Caries Prevention

Yanti¹,

Armidin²

2018

Proceedings of the 2nd Public Health International Conference (PHICo 2017)

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Abstract__ Herbal mouthwash is considered as an alternative regimen in maintaining oral hygiene. Tea contains compounds such as catechin and tannin which possess bactericidal and bacteriostatic effect which helps to prevent dental caries. This study was conducted to determine the effectiveness between rinsing with steeping black tea and green tea solution in decreasing the amount of oral bacteria. This is an experimental study with pre and post test controlled group design. The sample were 90 Junior High School students from Swasta Namira School which were then divided into three groups: oral rinsing with steeping black tea (treatment group), oral rinsing with steeping green tea (treatment group) and oral rinsing with aquadest (control group). Saliva collection was carried out before treatment (pre test/ baseline) and after treatment (post test). Treatment group was instructed to rinse 15 ml of steeping black and green tea solution whereas control group were instructed to rinse 15 ml aquadest for 30 seconds and get rid of it. The saliva samples before and after treatment were brought to the microbiology laboratorium for bacteria amount calculation using Total Plate Count (TPC) method. A T-test were used to determine the difference between rinsing with black tea and green tea and Kruskalwalis used to determine the difference between rinsing with steeping black tea, steeping green tea and aquadest towards the mean amount of bacteria before and after treatment. The results showed significant reduction in amount of bacteria in both treatment group where black tea group before treatment 1002.13x10 ±494.55x103 CFU/ml (p>0.05). Thus, it can be concluded that rinsing with steeping black tea solution has the same effectiveness in decreasing the total oral bacteria as compared to green tea solution.

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Comparative Study of the Antibacterial Effect of Mouth Washes and Vernonia amygdalina (del.) on Some Tooth Decay Causing Bacteria

Abstract: Aims: To determine the antibacterial effect of the ethanol stem extract of Vernonia amygdalina (bitter-leaf) and some mouth washes against some bacteria that have been implicated in causing tooth decay so as to establish the role of herbal medicine and chemical compounds in oral hygiene.

Cited by 10 publications

References 15 publications

PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF Vernonia amygdalina: A REVIEW

PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF Vernonia amygdalina: A REVIEW

Antibacterial Assessment of Crude and Fractionated Extracts of Vernonia amygdalina Leaf against Multiple Antibiotic Resistant Bacteria of Wound Infection

Effectiveness of Rinsing Black Tea Compared to Green Tea in Decreasing Oral Bacterial Counts as an Alternative of Caries Prevention

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