Comparative study of the carnitine, Gensing, Dill, and Arginine effect in sperm of normal and experimentally H2O2 induced oxidative stres albino male rats

Abstract

The aim of this study is to compare the effects of Carnitine, Gensing, Dill and Arginine in characteristics of the sperms:total sperm, percentage of live and dead sperm, normal and abnormal sperm in male normal and exposuedrats to oxidative stress induced by hydrogen peroxide H2O2(0.5%) in drinking water during the experiment for 30 days. Fifty male rats used in age 12-14 weeks in weights (300-325g) divided randomly into 10 groups, included 5 in each group as following. 
 Control, H2O2 , Carnitine , carnitine + H2O2 , Gensing , Gensing + H2O2, Dill, Dill+ H2O2, Arginine, Arginine + H2O2 groups.
 Results showed:
 1- Treating normal rats with Carnitine, Gensing , Dill, Arginine, led to a significant increase in value(P≤0.05) in Total sperm, percentage of live sperm, and a significant decrease in dead sperm and no difference in normal and abnormal sperm percentage comparing to control group.
 2- Oxidative stress Induced by H2O2 led to significant increase in value (P≤ 0.05) in percentage of abnormal sperm comparing to control group. While there were a significant decrease in value (P≤0.05) in Total sperm, percentage of live and normal sperm.
 3- Treating rats exposure to oxidative stress with Carnitine, Gensing, Dill, Arginine, led to a significant decrease in value (P≤0.05) in percentage of abnormal and dead sperm, While the treating led to significant increase in Total sperm, percentage of live and normal sperm.