Comparative study of the impact of 3- versus 8-month neoadjuvant hormonal therapy on outcome of laparoscopic radical prostatectomy

Pu, Xiao‐Yong; Wang, Xinghuan; Wu, Yi‐Long; Wang, Huaipeng

doi:10.1007/s00432-007-0204-2

Cited by 17 publications

(32 citation statements)

References 27 publications

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“…Drains were removed in all patients before discharge. Catheters were removed after a mean (range) of 6.1 (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) days, all with no previous cystogram. Twenty-nine patients had a modified pelvic lymphadenectomy.…”

Section: Resultsmentioning

confidence: 99%

“…LRP was performed using the Montsouris technique, with some modifications by us [10][11][12][13]. In brief, after the puboprostatic space is developed, the bilateral endopelvic fascia of the prostate is dissected longitudinally toward the apex and puboprostatic ligament section.…”

Section: Surgical Proceduresmentioning

confidence: 99%

“…Based on our previous experiences [10][11][12], in this study, we evaluated the medium-term oncological and functional results after LRP at our institute.…”

mentioning

confidence: 99%

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Laparoscopic radical prostatectomy: oncological and functional results of 126 patients with a minimum 3-year follow-up at a single Chinese institute

Gao¹,

Zhou²,

Li³

et al. 2009

Asian J Androl

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In this study we evaluate the oncological and functional results of the largest cohort of patients in China treated by laparoscopic radical prostatectomy (LRP) and with at least 3 years of follow-up. 126 inconsecutive patients (range 56-78 years, median 62.5) who had an LRP were retrospectively analyzed. The mean prostate specific antigen level and Gleason score was 13.4 ng mL -1 and 6.4, respectively. Twenty-seven patients had unilateral or bilateral nerve preservation and 29 had pelvic lymphadenectomy. Multivariate analysis was used to adjust for differences in clinical and pathological features when comparing the risk for biochemical progression-free survival (bPFS). Urinary continence was assessed by incontinence questionnaire and erectile function by the Sexual Health Inventory for Men score. The mean operative duration was 250 min and blood loss 354 mL. Five patients received blood transfusion and nine had complications, including rectal injury (two), ureteral injury (one), active bleeding (one), bladder neck stenosis (two), paralytic ileus (one), subcutaneous hematoma (one) and port-site hernia (one). The overall positive surgical margin rate was 20.6% and correlated with pathological stage and Gleason score respectively (P = 0.03, P < 0.001 respectively). All patients had ≥ 3 years of follow-up (range 3-6.75 years, mean 4.6, median 4.75). At 3 years of follow-up, the overall survival rate was 100% and the bPFS was 81.0% in all patients; 124 patients (98.4%) were continent; 22 of 27 patients (81.5%) who underwent nerve preservation retained erectile function. Our series confirms that LRP is an effective, safe and precise technique at Chinese institution.

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Section: Resultsmentioning

confidence: 99%

Section: Surgical Proceduresmentioning

confidence: 99%

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Laparoscopic radical prostatectomy: oncological and functional results of 126 patients with a minimum 3-year follow-up at a single Chinese institute

Gao¹,

Zhou²,

Li³

et al. 2009

Asian J Androl

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“…It has been regarded as a good choice for localized prostate cancer in China (Pu et al 2007). Since the transperitoneal LRP was Wrst performed (Schuessler et al 1992), until 6 years later, Guillonneau et al (1998) reported an initial series of 28 cases with a standardized technique based on the primary access to the seminal vesicles.…”

Section: Discussionmentioning

confidence: 99%

“…Time to continence recovery was signiWcantly shortened in LRP. Based on Steiner's technical considerations and our previous experience (Pu et al 2007;Steiner 2000aSteiner , 2000bSteiner , 2000c), we conducted a simple apical dissection of the prostate in LRP. In this study, we described the modiWed technique in LRP and evaluated the early recovery of urinary continence.…”

Section: Introductionmentioning

confidence: 99%

Modified apical dissection of the prostate improves early continence in laparoscopic radical prostatectomy: technique and initial results

Gao

Wang

et al. 2009

J Cancer Res Clin Oncol

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The Training Courses of Urological Laparoscopy

Sun¹,

Smith²,

Yang³

2012

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Comparative study of the impact of 3- versus 8-month neoadjuvant hormonal therapy on outcome of laparoscopic radical prostatectomy

Abstract: The prolonged NHT (8-month) did not affect the operative or postoperative parameters. The LRP can be safely performed in patients after prolonged NHT. Prospective randomized studies are required to determine whether prolonged NHT reduces the risk of biochemical recurrence after LRP.

Cited by 17 publications

References 27 publications

Laparoscopic radical prostatectomy: oncological and functional results of 126 patients with a minimum 3-year follow-up at a single Chinese institute

Laparoscopic radical prostatectomy: oncological and functional results of 126 patients with a minimum 3-year follow-up at a single Chinese institute

Modified apical dissection of the prostate improves early continence in laparoscopic radical prostatectomy: technique and initial results

The Training Courses of Urological Laparoscopy

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