Comparative Study of the Influence of Helium and Argon Plasma on Crystallogenic Properties of the Blood

Мартусевич, А. К.; Galka, A. G.; Golygina, Elena S.; Fedotova, Alexandra S.; Tuzhilkin, Alexander N.; Malinovskaya, S. L.

doi:10.1615/plasmamed.2021038035

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…Cold plasma generation was performed using a device of an original design using the principle of microwave ionization of a gas stream [25,26]. The gas supply rate was strictly controlled for all procedures.…”

Section: Methodsmentioning

confidence: 99%

Microwave study of the effect of cold argon plasma on functional state of rat’s skin

Martusevich,

Nazarov,

Surovegina

et al. 2024

BIO Web Conf.

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The purpose of this study was a comparative study of the dielectric parameters of rat skin when treated with argon and argon cold plasma. The experiment was performed on 40 male Wistar rats divided into 4 equal groups. The first group of animals (n=10) was a control (intact). The rats of the remaining groups (n=10 in each) were treated daily with a pre-epilated area of the skin of the back (area = 1x1 cm). The duration of the course for all experienced groups is 10 procedures. Animals of the second group were treated with a non–ionized argon stream (the duration of one procedure was 1 minute), rats of the third and fourth groups were treated with argon cold plasma (1 and 2 minutes, respectively). Cold plasma generation was performed using a device using the principle of microwave ionization of a gas stream. Argon of high purity (99.99%) was used as the latter. The dielectric parameters of the skin of animals in the treated area (in control group rats – at a similar point in the back) were evaluated upon completion of a full course of exposure. For this purpose, a specialized software and hardware complex was used, providing near-field resonant microwave probing of biological tissues. It was found that the course treatment of the skin of the back of rats with gas streams with different ionization causes the formation of a specific functional-metabolic and morpho-structural response. Its character is determined by the parameters of the gas flow used: non-ionized argon significantly reduces the dielectric parameters (permeability and conductivity), and the result of the action of cold argon plasma depends on the exposure. During one-minute treatment, tissue permeability was observed to remain intact with a moderate decrease in conductivity. In the case of an increase in the exposure time to 2 minutes, the dielectric constant increased, and the conductivity remained unchanged.

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Section: Methodsmentioning

confidence: 99%

Microwave study of the effect of cold argon plasma on functional state of rat’s skin

Martusevich,

Nazarov,

Surovegina

et al. 2024

BIO Web Conf.

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“…A separate issue is the clarification of the role of the carrier gas in the implementation and features of the action of cold plasma on biological objects. To solve this problem, we compared the modification of the physicochemical properties of blood plasma during its treatment with helium and argon plasma [ 64 ]. It was found that the use of helium as a carrier gas provides a more physiological response of the biosystem, contributing to the optimization of the crystalloscopic picture of the biological fluid.…”

Section: The Authors’ Own Research In the Field Of Studying Local And...mentioning

confidence: 99%

Cold Argon Athmospheric Plasma for Biomedicine: Biological Effects, Applications and Possibilities

et al. 2022

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Currently, plasma medicine is a synthetic direction that unites the efforts of specialists of various profiles. For the successful formation of plasma medicine, it is necessary to solve a large complex of problems, including creating equipment for generating cold plasma, revealing the biological effects of this effect, as well as identifying and justifying the most promising areas of its application. It is known that these biological effects include antibacterial and antiviral activity, the ability to stimulate hemocoagulation, pro-regenerative properties, etc. The possibility of using the factor in tissue engineering and implantology is also shown. Based on this, the purpose of this review was to form a unified understanding of the biological effects and biomedical applications of argon cold plasma. The review shows that cold plasma, like any other physical and chemical factors, has dose dependence, and the variable parameter in this case is the exposure of its application. One of the significant characteristics determining the specificity of the cold plasma effect is the carrier gas selection. This gas carrier is not just an ionized medium but modulates the response of biosystems to it. Finally, the perception of cold plasma by cellular structures can be carried out by activating a special molecular biosensor, the functioning of which significantly depends on the parameters of the medium (in the field of plasma generation and the cell itself). Further research in this area can open up new prospects for the effective use of cold plasma.

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Experimental Evaluation of the Effect of Argon Cold Plasma on Oxidative Metabolism of the Blood

et al. 2022

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Comparative Study of the Influence of Helium and Argon Plasma on Crystallogenic Properties of the Blood

Cited by 5 publications

References 27 publications

Microwave study of the effect of cold argon plasma on functional state of rat’s skin

Microwave study of the effect of cold argon plasma on functional state of rat’s skin

Cold Argon Athmospheric Plasma for Biomedicine: Biological Effects, Applications and Possibilities

Experimental Evaluation of the Effect of Argon Cold Plasma on Oxidative Metabolism of the Blood

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