Comparative study on xanthan gum and hydroxypropylmethyl cellulose as matrices for controlled-release drug delivery I. Compaction and in vitro drug release behaviour

Starch-free grewia gum matrices: Compaction, swelling, erosion and drug release behaviour

“…Such materials which are abundant in nature and, can also be cultivated, remain largely undeveloped. Plant polysaccharides are one particular resource that could be used as 45 alternative excipients and have come under increasing research focus in the design of dosage forms for oral controlled release administration (Naggar et al, 1992;Bonferoni et al, 1993;Kristmundsdo´ ttir et al, 1995;Sujja-areevath et al, 1996;Talukdar et al, 1996;Khullar et al, 1998;Vervoort et al, 1998;Munday and Cox, 2000;Mughal et al, 2011;Nep 2015).…”

Development and characterization of sponge-like acyclovir ocular minitablets

“…This finding was in agreement with Ughini et al (2004), who reported that all studied formulations containing xanthan gum showed prolonged release profiles. Furthermore, xanthan gum was proved to have higher drug-retarding ability than the well known HPMC (Talukdar et al, 1996).…”

Evaluation of sesamum gum as an excipient in matrix tablets

“…Naturally occurring polymers are increasingly becoming the focus of research on hydrophilic matrices for oral controlled release (Naggar et al, 1992;Bonferoni et al, 1993;Kristmundsdo´ttir et al, 1995;Sujja-areevath et al, 1996;Talukdar et al, 1996;Khullar et al, 1998;Vervoort et al, 1998;Nep 2015). They hydrate and swell on contact with water forming the gel layer controlling drug release from the tablet matrices.…”