Comparative Visual Outcome Analysis of a Diffractive Multifocal Intraocular Lens and a New Diffractive Multifocal Lens with Extended Depth of Focus

Abstract

This study compares the visual and refractive performance of the TECNIS Synergy (DFR00V-DFW150-225-300-375) multifocal intraocular lens (IOL) and the AcrySof IQ PanOptix (TFAT00-30-40-50-60) multifocal IOL. Patients who underwent phacoemulsification and cataract extraction and received either a multifocal Synergy or PanOptix IOL were included. Monocular uncorrected distance (UDVA), intermediate (UIVA), near (UNVA), and corrected distance (CDVA) visual acuities were assessed at three and six months postoperatively. Secondary outcome measures of photic phenomena were also assessed. A total of 140 patients (224 eyes) were included in this study, with 69 patients (105 eyes) in the Synergy group and 71 patients (119 eyes) in the PanOptix group. There were no statistically significant differences in UIVA or CDVA measurements across all time points. When assessing UDVA, at three months postoperatively, there were more eyes in the PanOptix group with vision better than 20/40 (p = 0.04). At three and six months postoperatively, the average UNVA was superior in the Synergy group (p = 0.01, 0.002). While the Synergy group reported more night vision disturbances at one and three months (p = 0.01, 0.03), the PanOptix group had more night vision disturbances at six months (p = 0.02). Although not statistically significant, the AcrySof IQ PanOptix multifocal IOL demonstrated better UDVA and UIVA sooner postoperatively than the TECNIS Synergy multifocal IOL. The Synergy IOL provided statistically better UNVA compared to the PanOptix IOL at three and six months postoperatively. Synergy patients reported more early photic phenomena than PanOptix patients, which later diminished.

Comparison of visual outcomes of bilateral dual-technology diffractive intraocular lens vs blended enhanced monofocal with dual-technology intraocular lens

“…However, as with every trifocal IOL, halos and glare persist at night. [15][16][17][18]31,32 The near and intermediate vision achieved using the ZFR00V IOL is excellent. The combination of enhanced monofocal lenses with such performances could lead to higher patient satisfaction, as determined by Labiris et al, who combined a monofocal IOL and trifocal IOL to yield better outcomes.…”

“…This design element splits incoming light, generating intermediate and near-addition powers. [15][16][17][18] Surgical Procedure All the procedures were consistently conducted by the same experienced surgeon, following standard protocols. Phacoemulsification was performed through a temporal clear corneal incision, and a foldable posterior chamber IOL (ZRF00V or ICB00) was inserted into the capsular bag.…”

“…The search for the best presbyopia correction method, with greater patient satisfaction and better visual results, leads to the search for better intraocular lenses. [16][17][18][19][20][21][22] The TECNIS Eyhance ICB00 IOL (Johnson & Johnson Vision) is a refractive monofocal lens with a modified anterior surface that aims to improve the range of vision compared with standard monofocal IOLs. However, Eyhance cannot be classified as an extended depth-of-focus (EDOF) IOL according to the American National Standard IOL criteria.…”

Visual Outcomes and Patient Satisfaction After Bilateral Refractive Lens Exchange with a Trifocal Intraocular Lens in Patients with Presbyopia

“…Synergy, a newer mixed EDOF and multifocal IOL, has been shown to deliver a high level of spectacle independence at near, intermediate, and distance. There is even some evidence showing that the Synergy may deliver better near visual acuity and mesopic contrast sensitivity compared to the PanOptix, which may improve patient satisfaction amongst myopes and patients who desire stronger near vision [ 35 ]. Few myopes were included in this study, but one patients with baseline myopia did report lower satisfaction due to the inability to see fine print up close postoperatively, while all other myopes reported good or very good satisfaction with the PanOptix IOL.…”

Outcomes and predictive factors in multifocal and extended depth of focus intraocular lens implantation

“…EDOF designs have generally been associated with decreased photic effects compared to trifocal designs [29][30][31], though some meta-analyses found that the incidence of halos is the same for EDOF compared with trifocal [32] or that there is insufficient information to compare the two IOLs [33]. 'Mix-andmatch' bifocal IOL implantation seems to also be superior to EDOF in terms of visual disturbances [34].…”