Comparing Anxiety and Depression in Patients With Takotsubo Stress Cardiomyopathy to Those With Acute Coronary Syndrome

Goh, Anne C.H.; Wong, Stephanie; Zaroff, Jonathan G.; Shafaee, Navid; Lundstrom, Robert J.

doi:10.1097/hcr.0000000000000152

Cited by 27 publications

(30 citation statements)

References 36 publications

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“…Our data do not appear to confirm the association between Tako-tsubo and anxious syndromes previously reported in literature [10, 12, 23]. …”

Section: Discussioncontrasting

confidence: 99%

“…However, the diagnosis was based on clinical records and therefore, not verified through semi-structured interviews, which is recognized as the method most capable to producing reliable diagnoses in psychiatry. Other surveys adopted screening by brief structured clinical interviews [10], questionnaires [11], or rating scales [12] but this is the first study to the best of our knowledge that used a more complex methodology.…”

Section: Discussionmentioning

confidence: 99%

“…Until now, studies have been conducted using methodologies that only allow broad diagnoses of groups of disorders, such as structured clinical brief interviews [10], questionnaires [11], or rating scales [12], which allow the detection of only anxious or depressive symptoms without a specific diagnosis label.…”

Section: Introductionmentioning

confidence: 99%

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Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Sancassiani¹,

Carta²,

Montisci³

et al. 2018

CPEMH

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Background:The aim was to study the association between mood and anxiety disorders and the Tako-Tsubo Syndrome (TTS) and to determine the role of antidepressants and the impairment of quality of life due the comorbid psychiatric disorder.Methods:Case-control study: 19 consecutive patients (17 female) with TTS compared to 76 controls without TTS, were randomly selected from the database of a nationwide epidemiological study after matching (gender, age and residence) by controls. Psychiatric diagnoses were carried out according to the ICD-10 using semi-structured interview tools (ANTAS-SCID) administered by clinical staff. Quality of Life (Qol) was assessed by means of SF-12.Results:Only Major Depressive Disorders (MDD) showed higher frequencies in cases with statistical significance difference (p=0.014) as well as at least one Mood Disorder Diagnosis [MDD or BD] (p=0.002). The lifetime prevalence of at least one anxiety disorder with no comorbid mood disorder did not show a higher frequency in cases (p=0.57).The score at SF-12 in the TTS group was similar to those of controls (p=0.71)In the TTS group, the score at SF-12 in people with one mood or anxiety diagnosis (N=7) was similar to those without mood or anxiety diagnosis (p=0.75). The use of antidepressants was higher in TTS group (15.79% vs 1.31%; p=0.030).Conclusion:The study shows an association between TTS with depressive disorders and antidepressants use and does not confirm the association with anxiety syndromes. The study suggests the need to investigate the possible interactions between antidepressants use and mood disorders in studies with appropriate design and sample size.

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“…Our data do not appear to confirm the association between Tako-tsubo and anxious syndromes previously reported in literature [10, 12, 23]. …”

Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Sancassiani¹,

Carta²,

Montisci³

et al. 2018

CPEMH

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“…One study found a greater impact of Post-Traumatic Stress Disorder (PTSD) after discharge (Salmoirago-Blotcher et al, 2016) in TTS compared to patients with myocardial infarction or healthy controls. Of interest, the time elapsing between the cardiac event and the psychological assessment was extremely variable, ranging from hours (Delmas et al, 2013) to years (Goh et al, 2016).…”

Section: Life-events and Psychological Traumamentioning

confidence: 99%

Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review

2019

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Objective: Takotsubo syndrome (TTS) is a transient heart disease that has been historically related to the occurrence of psychological (emotional) factors ("broken heart" syndrome). We aimed to conduct a systematic review analyzing the role of psychological factors in TTS. Methods: All studies on TTS and psychological factors from January 1991 through April 2019 were scrutinized according to the Cochrane Collaboration and the PRISMA statements. Selected studies were additionally evaluated for the Risk of Bias according to the Newcastle-Ottawa Scale (NOS). Results: Fifteen case-control studies (by Mayo Clinic criteria) were finally selected. Most studies analyzed stressful life-events or trauma, although with conflicting findings, while a likely role of long-lasting psychological distress seemed to be a homogenous result. Among lifetime psychopathology, only anxiety appeared to have a significant role. Some studies outlined a likely role of personality, but findings are conflicting. Conclusion: Our findings do not lead to any definitive assumption on the specific role of psychological factors in TTS, also for scant strong methodology of the most part of the studies. More studies with stronger research methodology are needed to better characterize psychological elements in TTS.

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“…The authors found that TCM patients had higher levels of chronic anxiety, but not chronic depression, in comparison with ACS patients. After a multivariable adjustment, chronic anxiety but not chronic depression was associated with TCM, and a history of chronic anxiety was associated with TCM status with an emotional trigger 20 . This implies that clinicians should focus on patients with chronic anxiety and a recent emotional trigger with respect to diagnosis and management of TCM.…”

mentioning

confidence: 99%

Takotsubo Cardiomyopathy and Psychiatric Illness: Redefining the Relationship

Masoud

2016

ICFJ

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Physicians who encounter patients in the emergency department with chest pain, palpitations, or shortness of breath may often find it difficult to differentiate diagnosis of panic attacks from acute coronary syndrome or Takotsubo Cardiomyopathy. Redefining and understanding the pathophysiological relationship of psychiatric illness including anxiety, depression, or panic attacks and Takotsubo Cardiomyopathy may help clinicians implement a more effective and beneficial model of care for this affliction that is being found to be increasingly more common in today’s age.

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Comparing Anxiety and Depression in Patients With Takotsubo Stress Cardiomyopathy to Those With Acute Coronary Syndrome

Abstract: In comparison with a control group with ACS, patients who presented with TSCM have higher levels of anxiety but not depression.

Cited by 27 publications

References 36 publications

Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Takotsubo Syndrome is Associated with Mood Disorders and Antidepressants Use, not with Anxiety and Impairment of Quality of Life Due to the Psychiatric Disorder

Traumatic Events, Personality and Psychopathology in Takotsubo Syndrome: A Systematic Review

Takotsubo Cardiomyopathy and Psychiatric Illness: Redefining the Relationship

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