Comparing complications of urethral stricture across various ages: a retrospective analysis of findings from retrograde urethrogram and voiding cysto-urethrogram over 10 years

Nnabugwu, Ikenna I; Onuh, Augustine C.; Anyimba, Solomon Kenechukwu; Mgbor, SO

doi:10.1186/s12880-019-0384-7

Cited by 3 publications

(1 citation statement)

References 23 publications

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“…It is most commonly seen in neurogenic bladder where there is disruption of the micturition reflex and this can occur at any level in the central nervous system from medulla to lumbar spine [2]. Although most commonly associated with neurogenic bladder, it is not pathognomy for it as Christmas tree bladder is sometimes or rarely seen in non-neurogenic conditions including urethral stricture [4].…”

Section: Discussionmentioning

confidence: 99%

Non-Neurogenic ‘Christmas Tree’ Urinary Bladder in A 30-Year-Old Man with Urethral Stricture: A Case Report

2024

IJCCR

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condition the urinary bladder appears elongated and pointed with a thickened, trabeculated wall likened to a Christmas tree. It is most commonly the result of neurogenic bladder from detrusor hyperreflexia which most commonly occurs after spinal trauma. Christmas tree bladder also may rarely be seen in cases of bladder neck obstruction of non- neurogenic cause. A 30-year-old male presented with two weeks history of leakage of urine par the perineum. There was prior history of urethral discharge, poor urinary stream, urine dribbling and dysuria. No history of genital trauma, urethral instrumentation or catheterization in past. Attempt at passage of urethral catheter failed. He subsequently had open supra pubic cystostomy. Ultrasonography shows multiple internal echoes in the urine with thickened irregular bladder wall. The upper urinary tract was normal. Combine RUG and VCUG demonstrate short segments strictures at the bulbar and membranous urethra. A track of contrast column was noted from the region of the bulbar stricture to the exterior consistent with urethro-cutaneous fistula. The urinary bladder appears large, elongated superiorly with irregular outline resembling ‘Christmas tree’ configuration.

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Section: Discussionmentioning

confidence: 99%

Non-Neurogenic ‘Christmas Tree’ Urinary Bladder in A 30-Year-Old Man with Urethral Stricture: A Case Report

2024

IJCCR

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Protocatechuic acid ameliorates testosterone‐induced benign prostatic hyperplasia through the regulation of inflammation and oxidative stress in castrated rats

Akanni

Owumi

Olowofela

et al. 2020

J Biochem & Molecular Tox

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Protocatechuic acid (PA) is a polyphenol—recognized for its efficacy as an antioxidant—possesses anticancer, anti‐inflammatory, antioxidant properties. The efficacy of PA in the management of benign prostatic hyperplasia (BPH) has not been investigated. Forty‐two castrated rats (n = 7) were treated as follows: control (corn oil), BPH only received testosterone propionate (TP) (TP 3 mg/kg intraperitoneally), BPH + PA (TP 3 mg/kg + PA 40 mg/kg), BPH + finasteride (Fin) (TP 3 mg/kg + Fin 10 mg/kg), PA only (40 mg/kg: by gavage), and Fin only (10 mg/kg: by gavage) for 4 weeks. In BPH rats, there were significant (P < .05) increases in prostatic (250%) and organosomatic (280%) weights compared with controls. Cotreatment decreased prostatic weights by 19% (PA) and 21% (Fin). Markers of inflammation: myeloperoxidase activities increased in serum (148%) and prostate (70%), as well as nitric oxide levels serum (92%) and prostatic (95%). Proinflammatory cytokines interleukin‐1β and tumor necrosis factor‐α increased by 3.6‐ and 2.8‐fold. Furthermore, prostatic malondialdehyde, superoxide dismutase, and serum total acid phosphatase increased by 97%, 25%, and 48%, respectively. Histology revealed poor architecture and severe proliferation of the prostate in BPH rats. Inflammation and oxidative stress markers, as well as the histological alteration in BPH rats, was attenuated (P < .05) upon cotreatment with PA and comparable with Fin cotreatment. These results suggest that PA mitigates oxido‐inflammatory responses and restored prostatic cytoarchitecture to levels comparable with control in rats induced with BPH.

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Uretroplastia en Fases Con Injerto De Mucosa Oral

Cabrera

Silva

2021

Rev. Gua. Uro.

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Introducción: La estrechez uretral es una de las principales causas de síntomas obstructivos en los hombres y con un impacto significativo en la vida por sus múltiples complicaciones. La uretroplastia en fases con injerto de mucosa oral ha devenido en una opción terapéutica para la estrechez uretral anterior compleja. Objetivo: Describir los resultados de la uretroplastia en fases con injerto de mucosa oral en la estrechez uretral anterior compleja. Metodología: Se realizó un estudio descriptivo, retrospectivo en 12 pacientes masculinos con estrechez uretral anterior compleja, en el Servicio de Urología del Hospital “Hermanos Ameijeiras”, de Cuba, entre 2016-2020. Resultados: La edad media de la serie fue 41,7 años. Predominó el antecedente de hipospadias, la localización péndulo-bulbar y la estrechez entre 6,1-7 cm. El 91,6% tenían más de un tratamiento previo fallido, y la estenosis uretral era severa (7,8). Predomino la re-estenosis con un 33,3%, que fue solucionada en dos pacientes, para un éxito de 83,3%. Los pacientes refirieron en un alto porcentaje mejoría de la calidad de vida y satisfacción con los resultados de la cirugía al completarse la segunda fase. Conclusiones: La uretroplastia en dos fases con injerto de mucosa oral es una opción terapéutica a considerar en la estrechez compleja de la uretra anterior por sus resultados satisfactorios

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Comparing complications of urethral stricture across various ages: a retrospective analysis of findings from retrograde urethrogram and voiding cysto-urethrogram over 10 years

Cited by 3 publications

References 23 publications

Non-Neurogenic ‘Christmas Tree’ Urinary Bladder in A 30-Year-Old Man with Urethral Stricture: A Case Report

Non-Neurogenic ‘Christmas Tree’ Urinary Bladder in A 30-Year-Old Man with Urethral Stricture: A Case Report

Protocatechuic acid ameliorates testosterone‐induced benign prostatic hyperplasia through the regulation of inflammation and oxidative stress in castrated rats

Uretroplastia en Fases Con Injerto De Mucosa Oral

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