Comparing Methadone Rotation to Consensus Opinion

Smith, Michael A.; Quirk, Kyle; Saul, D'Anna; Rodgers, Philip T.

doi:10.1016/j.jpainsymman.2019.09.014

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“…28 More recently, in a retrospective study, a successful OS was defined as at least a 30% reduction in either baseline pain score or as-needed medication use sustained for at least 3 consecutive days. 31 In another study, OS was considered efficacious if it led to a ≥ 2-point decrease in pain scores within 1 week of OS. 6 These methods focused on pain measurement only, and the number of as-needed medications cannot reflect changes in background pain.…”

Section: Discussionmentioning

confidence: 99%