Comparing the Performance of Different Instruments for Diagnosing Frailty and Predicting Adverse Outcomes among Elderly Patients with Gastric Cancer

Ding, Lei; Miao, Xueyi; Jin, Lu; Hu, Jie; Xu, Xinyi; Zhu, Huayun; Xu, Qi; Zhu, Shuqin

doi:10.1007/s12603-021-1701-8

Cited by 17 publications

(17 citation statements)

References 38 publications

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“…The study by Ding et al . argued that the TFI could predict postoperative complications from multiple dimensions among elderly patients with gastric cancer, but its predictive ability still required further improvement 16 . Preoperative comorbidity presents as a common problem in patients with cancer.…”

Section: Discussionmentioning

confidence: 99%

“…The sample size was calculated according to the PASS 15.0 (PASS 15 Power Analysis and Sample Size Software, NCSS, LLC, Kaysville, UT, USA). One previous study described that the prevalence of total complications among postoperative patients with gastric cancer was 22.8% 16 . The minimum sample in this study was 362 patients, based on a 20% missing rate.…”

Section: Methodsmentioning

confidence: 98%

“…One previous study described that the prevalence of total complications among postoperative patients with gastric cancer was 22.8%. 16 The minimum sample in this study was 362 patients, based on a 20% missing rate.…”

Section: Study Design and Participantsmentioning

confidence: 99%

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A web‐based calculator combining Geriatric Nutritional Risk Index (GNRI) and Tilburg Frailty Indicator (TFI) predicts postoperative complications among young elderly patients with gastric cancer

Miao

Ding

et al. 2023

Geriatrics Gerontology Int

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Nutritional status and frailty are significant indicators reflecting physiological reserve. We sought to establish and validate a web-based calculator containing the Geriatric Nutritional Risk Index (GNRI) and the Tilburg Frailty Indicator (TFI) together with general clinical information to predict total complications among elderly patients with gastric cancer.Methods: This was a prospective cohort study of 582 elderly patients with gastric cancer in a tertiary hospital in China. Nutritional status and frailty were assessed by the GNRI and the TFI, respectively. The nomogram was built and further converted into a web-based calculator. The receiver operating characteristic analysis was performed to evaluate the discrimination of the nomogram. Calibration was assessed using the calibration curve and Hosmer-Lemeshow test via the bootstrap resampling procedure. The decision curve analyses (DCAs) were employed to quantify the net benefits of a certain threshold probability for assessing the clinical values. Results:The GNRI (odds ratio [OR], 0.921; 95% confidence interval [CI], 0.895-0.949; P < 0.001), the TFI (OR, 1.243; 95% CI, 1.113-1.386; P < 0.001), surgical approach (OR, 1.913; 95% CI, 1.073-3.408; P = 0.028) and comorbidity (OR = 1.599, 95% CI = 1.028-2.486, P = 0.037) were independently associated with total complications. The nomogram demonstrated good discrimination (area under the receiver operating characteristic curve: training cohort, 0.735; validation cohort, 0.777) and calibration (P = 0.135). The DCA curves of the nomogram also showed good positive net benefits. Conclusions:The web-based calculator incorporating the GNRI, the TFI, surgical approach, and comorbidity could successfully predict total complications among elderly patients with gastric cancer with good accuracy in a convenient manner.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 98%

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A web‐based calculator combining Geriatric Nutritional Risk Index (GNRI) and Tilburg Frailty Indicator (TFI) predicts postoperative complications among young elderly patients with gastric cancer

Miao

Ding

et al. 2023

Geriatrics Gerontology Int

Self Cite

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“…The instruments in comprehensive TCM hospitals are more advanced than those in primary hospitals, and their convenience of use is also significantly better. 53 Regarding efficiency, wearable devices can help young TCM doctors obtain historical information about patients in advance, which may assist in making a diagnosis; this may explain the finding that the TCM doctors aged <40 years scored 9.1 times higher than the TCM doctors aged ≥40 years. 54 In the same vein, the findings showed that younger TCM doctors and TCM doctors with low titles had higher mean scores for reliability, convenience, and usefulness of TCM diagnostic instruments.…”

Section: Misdiagnosis Ratementioning

confidence: 99%

Perceptions of traditional Chinese medicine doctors about using wearable devices and traditional Chinese medicine diagnostic instruments: A mixed-methodology study

Zhou

Ogihara

et al. 2022

DIGITAL HEALTH

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Objective This study aimed to investigate the perceptions of traditional Chinese medicine doctors about wearable devices and diagnostic instruments and explore the factors that influence them. Methods Data on the perceptions of the traditional Chinese medicine doctors in Hangzhou, China, about wearable devices and diagnostic instruments were collected through face-to-face semi-structured interviews. The author coded the interview responses using grounded theory. A cross-sectional survey was conducted in four traditional Chinese medicine hospitals in Hangzhou, China. The responses of 385 traditional Chinese medicine doctors were considered valid. Descriptive statistics and binary logistic regression models were used for analysis. Results This study categorized the perceptions of traditional Chinese medicine about wearable devices and traditional Chinese medicine diagnostic instruments under convenience, reliability, suitable population, machine usage scenario, and the integration of traditional Chinese medicine and information communication technology. Convenience encompassed portability and the convenience of carrying instruments or wearing the devices and operating them and the human–device interface. Reliability encompassed the underlying principles, accuracy, durability, and reference to diagnosis. Suitability for people encompassed age distinction and disease differentiation. Machine usage scenarios included use in daily life, educational institutions, and primary medical institutions. The combination of traditional Chinese medicine and information communication technology encompassed the integration of traditional Chinese medicine and wearable functions and diagnostic interpretation. The perceptions of traditional Chinese medicine doctors were affected by age, title, type of hospital, and specialty. Conclusions The use of wearable devices and traditional Chinese medicine diagnostic instruments has gradually been accepted by traditional Chinese medicine doctors. Traditional Chinese medicine doctors need to improve their knowledge and skills for information communication technology integration, and their standardized training should incorporate information communication technology and digital health.

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“…Only postoperative complications that developed during hospitalisation were considered for total complications [32]. Based on previous studies, total complications were considered as Clavien-Dindo classi cation ≥ 2 [33]. Increased hospital costs were de ned as costs greater than the 75th percentile of the entire cohort [34].…”

Section: Outcome Measuresmentioning

confidence: 99%

Predictive value of frailty assessment tools in patients undergoing surgery for gastrointestinal cancer

Hui-pin

Zhang

Zhou

et al. 2022

Preprint

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Purpose We used three commonly used frailty assessment tools to investigate the current status of preoperative frailty and to analyse their predictive value for prognosis in patients undergoing surgery for gastrointestinal cancer. Methods This single-centre, observational, prospective cohort study was conducted at the Affiliated Lianyungang Hospital of Xuzhou Medical University from August 2021 to July 2022. A total of 229 patients aged ≥ 18 years who underwent surgery for gastrointestinal cancer were included in this study. We collected the patients’ baseline data and used the Comprehensive Geriatric Assessment (CGA), Fried Phenotype (FP), and the FRAIL scale to assess frailty. The outcome measures were the complications experienced by patients and increased hospital costs. Results The prevalence of frailty was assessed using the CGA, FP, and FRAIL scale which returned the results 65.9%, 47.6%, and 34.9%, respectively. Multivariate logistic analysis confirmed that CGA was independently associated with increased hospital costs (OR = 2.514, 95% CI [1.202–5.258]; p = 0.014), and none of the frailty assessment tools were associated with total complications. Conclusions CGA was an independent predictor of increased hospital costs in patients undergoing surgery for gastrointestinal cancer.

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Comparing the Performance of Different Instruments for Diagnosing Frailty and Predicting Adverse Outcomes among Elderly Patients with Gastric Cancer

Cited by 17 publications

References 38 publications

A web‐based calculator combining Geriatric Nutritional Risk Index (GNRI) and Tilburg Frailty Indicator (TFI) predicts postoperative complications among young elderly patients with gastric cancer

A web‐based calculator combining Geriatric Nutritional Risk Index (GNRI) and Tilburg Frailty Indicator (TFI) predicts postoperative complications among young elderly patients with gastric cancer

Perceptions of traditional Chinese medicine doctors about using wearable devices and traditional Chinese medicine diagnostic instruments: A mixed-methodology study

Predictive value of frailty assessment tools in patients undergoing surgery for gastrointestinal cancer

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