2011
DOI: 10.1292/jvms.10-0528
|View full text |Cite
|
Sign up to set email alerts
|

Comparison between Immunohistochemistry and Genetic Clonality Analysis for Cellular Lineage Determination in Feline Lymphomas

Abstract: ABSTRACT. Clinical application of genetic clonality analysis by PCR has been available in feline lymphoma. However, it is in under dispute whether the analysis can be applied for cellular lineage determination. To evaluate utility of the analysis for lineage determination, the results between immunohistochemistry and the genetic analysis were compared. Based on the result with immunohistochemistry, sensitivity of the primer for IgH was 89% and specificity was 75%. Sensitivity of the primer for TCR was 25% and… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

2
25
0
1

Year Published

2013
2013
2021
2021

Publication Types

Select...
5
1

Relationship

1
5

Authors

Journals

citations
Cited by 15 publications
(28 citation statements)
references
References 13 publications
(19 reference statements)
2
25
0
1
Order By: Relevance
“…Comparison between the two analyses showed similar results with a previous study [18]. Of 17 cases with T-cell lymphoma determined by immunohistochemistry, 4 cases (24%) showed clonal rearrangement of IgH.…”
Section: Discussionsupporting
confidence: 86%
See 4 more Smart Citations
“…Comparison between the two analyses showed similar results with a previous study [18]. Of 17 cases with T-cell lymphoma determined by immunohistochemistry, 4 cases (24%) showed clonal rearrangement of IgH.…”
Section: Discussionsupporting
confidence: 86%
“…Of 17 cases with T-cell lymphoma determined by immunohistochemistry, 4 cases (24%) showed clonal rearrangement of IgH. Such a repugnant phenomenon in feline lymphoma has been already reported and discussed previously as the crosslineage rearrangement [18].…”
Section: Discussionsupporting
confidence: 51%
See 3 more Smart Citations