Comparison between manual and automated CT liver volumetry in assessment of the liver volume in living donor liver transplantation

Abstract

Aim of the work To evaluate the effectiveness and advantages of automated CT volumetry in the assessment of liver volume in living donor liver transplantation and to compare this technique and its results with those calculated from manual volumetry. Materials and Methods This comparative study was conducted on dynamic contrast enhanced hepatic CT scans of 21 potential living liver donors. All potential donors underwent 1st step laboratory investigations to enter the 2nd step investigations for living donor liver transplantation operation. Automated liver volumetry was developed using the Myrian® XP-Liver software. To establish reference standard liver volumes, a radiologist manually traced the contour of the liver on each CT slice. We compared the results obtained with automated with those obtained with the reference standard for this study, manual volumetry. Results The study showed that automated CT liver volumetry achieved excellent agreement with manual volumetry without statistical significance. The average processing times for automated volumetry was 3.09 ± 0.44 min/case, whereas those for manual volumetry were 16.23 ± 0.81 min/case, the difference was statistically significant (p < 0.05). Conclusion Automated CT liver volumetry performed using the Myrian® XP-Liver software can accurately predict the preoperative liver volume and provide acceptable measurements comparable to the gold standard manual volumetry.