Comparison Between Nomograms Used to Define Pediatric Aortic Arch Hypoplasia: Retrospective Evaluation Among Patients Less Than 1 Year Old with Coarctation of the Aorta

Şişli, Emrah; Kalın, Sevinç; Tuncer, Osman Nuri; Ayık, Mehmet Fatih; Alper, Hüdaver; Levent, Reşit; Şahin, Hatice; Atay, Yüksel

doi:10.1007/s00246-019-02130-2

Cited by 8 publications

(5 citation statements)

References 28 publications

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“…An image-based computational uid dynamics (CFD) approach based on Navier Stokes equations is therefore proposed and expected to solve, at source, the current state of the art in terms of the multiplicity of diagnostic criteria for this condition, diversity of treatment modalities, leading to "off" clinical diagnosis and treatment [14]. For example, preoperative diagnosis of aortic arch dysplasia without the need for severing anastomosis surgery after intraoperative release.…”

Section: Discussionmentioning

confidence: 99%

Coarctation of Aorta Computational Fluid Dynamics Analysis after Three-Dimensional Reconstruction and Clinical Application

Pan

et al. 2023

Preprint

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Objective: To investigate the clinical significance of Computational Fluid analysis in diagnosing and treating coarctation of aorta after three-dimensional reconstruction of CTA. Methods: The clinical data and imaging data of 40 children with coarctation of aorta and 24 normal children were retrospectively analyzed and summarized, and combined with statistical means and computational fluid dynamics and explored the potential of clinical application. Results: (1) Computational fluid pressure difference and color Doppler pressure difference analysis were performed in 40 children with coarctation of aortic arch and 24 normal children.There was no significant difference (P > 0.05) in fluid pressure between the 40 patients with coarctation group was 63.1 ± 5.1 mmHg compared with its preoperative color ultrasound pressure difference (64.1 ± 5.2 mmHg), whereas there was a significant difference (P <0.01 ) in fluid pressure between the 40 patients with coarctation of aorta and 24 patients with normal aortic arch was (4.4 ± 1.0) mmHg ;(2) After three-dimensional reconstruction, computational fluid dynamics analysis was performed to analyze the changes in pressure gradient along the aortic path, mainly in the constricted segment, and in-depth discussion and analysis were conducted. The measured pressure drop at the largest constricted segment in the constricted group was greater than 35 mmhg, while the corresponding pressure drop in the normal group children was less than 10 mmhg. The fluid vector graph showed a sharp decrease in pressure in the constricted segment, which was significantly different from the normal group. Conclusion: Computational fluid dynamics for the diagnosis and treatment of coarctation of aorta is consistent with clinical imaging analysis methods; As a new tool for the diagnosis of coarctation of aorta , Computational fluid dynamics has the same clinical benefits, but also has many advantages that imaging does not have. Its application range is broader. Although the current sample size is not sufficient to develop new diagnostic standards, three-dimensional reconstruction of fluid dynamics analysis can provide a lower cost, less patient pressure, less uncertainty, and more accurate and intuitive assessment of the overall pressure change process of the aortic arch, It has a more comprehensive and systematic guiding significance for the diagnosis and treatment of children with coarctation of aorta.

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Section: Discussionmentioning

confidence: 99%

Coarctation of Aorta Computational Fluid Dynamics Analysis after Three-Dimensional Reconstruction and Clinical Application

Pan

et al. 2023

Preprint

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“…TTE also allows a comprehensive assessment of LV function, LV mass and associated cardiac anomalies such as a bicuspid aortic valve. An important aspect of the anatomical assessment is to detect hypoplasia of the aorta, since this will greatly affect the surgical technique employed for repair, with systematic analysis of each segment of the arch in relation to age-matched Z scores [ 40 , 41 , 42 ].…”

Section: Paediatric and Adult Echocardiographymentioning

confidence: 99%

Coarctation of the Aorta: Diagnosis and Management

et al. 2023

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Coarctation of the aorta (CoA) accounts for approximately 5–8% of all congenital heart defects. Depending on the severity of the CoA and the presence of associated cardiac lesions, the clinical presentation and age vary. Developments in diagnosis and management have improved outcomes in this patient population. Even after timely repair, it is important to regularly screen for hypertension. Patients with CoA require lifelong follow-up with a congenital heart disease specialist as these patients may develop recoarctation and complications at the repair site and remain at enhanced cardiovascular risk throughout their lifetime.

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“…В исследовании E. Sisli и соавт. [22] сравнивались значения оценки выраженности гипоплазии дуги аорты по номограммам Cantinotti, Pettersen и Lopez. Несмотря на наличие корреляции между ними, результаты оценки существенно отличались друг от друга.…”

Section: оригинальные статьиunclassified

Influence of intrauterine hemodynamics on the C segment of the aortic arch in the fetus

Хубулава¹,

Марченко²,

Naumov³

et al. 2021

Ross. vestn. perinatol. pediatr.

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Objective. To assess the correlation between the hemodynamic characteristics of the left ventricle and geometric features of the aortic arch in the fetus.Methods. The study involved 31 fetuses from 29 to 34 weeks of gestation by echocardiography. The scientists assessed the morphogeometric characteristics of the left ventricle andaortic arch. They studied the following parameters: end-diastolic volume ofthe left ventricle (LVEDV), stroke volume of the leftventricle (LVSV), velocity-time integral of the flow through aortic valve (VTI AV), diameter of the aortic valve ring (AV), diameterof the aortic arch segment between brachiocephalic trunk and left carotid artery (dС). Results. The average gestational age was 31,9±1,4weeks (95% CI: 31,4–32,4 weeks). Average body weight 1899±377 g (95% CI: 1762–2038 g). LVEDV = 1,57±0,64 ml (95% CI: 1,3–1,8). LVSV = 1,3±0,45 ml (95% CI: 1,1–1,4 ml). AV 0,4±0,07 cm (95% CI: 0,39–0,44 cm). C segment of the aorticarc is 0,37±0,07 cm (95% CI: 0,035–0,040 cm). There was direct correlation between the variables used to calculate dC (Pearson correlation coefficient: LVEDV = 0,51; p=0,002; LVSV = 0,46; p=0,005; AV = 0,52, p=0,001). The diameter of the C segment of the aortic arch can be calculated using the following equations: dС= 0,76· LVSV +2,8 (95% CI LVSV 0,2–1,3 95% CI for constant2,1–3,6; Fisher’s criterion 7,6 р=0,01). dС= 0,59· LVEDV +2,8 (95% CI LVEDV 0,2–0,98; 95% CI for constant 2,2–3,5; Fisher’s criterion 10 р=0,004). dС= 0,59·AV+1,3 (95% CI AV 0,22–0,95; 95% CI for constant – 0,23–2,9; Fisher’s criterion 10,7;р=0,003).Conclusion. 1)hemodynamic characteristics of the left ventricle allow predicting the sizeof the aortic arch in fetuses from 29 to 34 weeks of gestation; 2)morphogeometric characteristics of the aortic arch are determined by the characteristics of the left ventricular stroke volume, end-diastolicvolume of the leftventricleand the sizeof the fibrous ring of the aortic valve.

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Comparison Between Nomograms Used to Define Pediatric Aortic Arch Hypoplasia: Retrospective Evaluation Among Patients Less Than 1 Year Old with Coarctation of the Aorta

Cited by 8 publications

References 28 publications

Coarctation of Aorta Computational Fluid Dynamics Analysis after Three-Dimensional Reconstruction and Clinical Application

Coarctation of Aorta Computational Fluid Dynamics Analysis after Three-Dimensional Reconstruction and Clinical Application

Coarctation of the Aorta: Diagnosis and Management

Influence of intrauterine hemodynamics on the C segment of the aortic arch in the fetus

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