2018
DOI: 10.1161/circulationaha.117.029987
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Comparison Between Patent Ductus Arteriosus Stent and Modified Blalock-Taussig Shunt as Palliation for Infants With Ductal-Dependent Pulmonary Blood Flow

Abstract: In this multicenter comparison of palliative PDA stent and BT shunt for infants with ductal-dependent pulmonary blood flow adjusted for differences in patient factors, there was no difference in the primary end point, death or unplanned reintervention to treat cyanosis. However, other markers of morbidity and pulmonary artery size favored the PDA stent group, supporting PDA stent as a reasonable alternative to BT shunt in select patients.

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Cited by 194 publications
(189 citation statements)
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“…Additionally, although not quite statistically significant, PDAs with Type II and Type III TI were more likely to have underlying shown in a large comparative study of surgical shunts versus PDA stents, PA size is both more symmetric and greater (using Nakata and symmetry indices) in a matched cohort of infants with ductal stents compared to the cohort with surgical shunt. 15 There are several noteworthy limitations to this study. It is important to recognize that PDAs are 3-dimensional structures and measurements made from 2D projectional angiography (obtained during these procedures from a practical standpoint), particularly with higher degrees of tortuosity, may be flawed.…”
Section: Discussionmentioning
confidence: 92%
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“…Additionally, although not quite statistically significant, PDAs with Type II and Type III TI were more likely to have underlying shown in a large comparative study of surgical shunts versus PDA stents, PA size is both more symmetric and greater (using Nakata and symmetry indices) in a matched cohort of infants with ductal stents compared to the cohort with surgical shunt. 15 There are several noteworthy limitations to this study. It is important to recognize that PDAs are 3-dimensional structures and measurements made from 2D projectional angiography (obtained during these procedures from a practical standpoint), particularly with higher degrees of tortuosity, may be flawed.…”
Section: Discussionmentioning
confidence: 92%
“…A retrospective multicenter cohort study was conducted on all infants less than 1 year of age with ductal dependent PBF and confluent branch and Children's Healthcare of Atlanta. 14,15 The study cohort consisted of the PDA stent cohort from a recent publication comparing outcomes of PDA stent placement and BT shunt placement. 15 Patients with discontinuous PAs or major aorto-pulmonary collateral arteries were excluded.…”
Section: Methodsmentioning
confidence: 99%
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“…Prospective studies comparing different approaches to securing a reliable pulmonary blood flow and shunt sizes could address some of these unresolved issues. Whether wider adaption of an interventional palliation (ductal stent or right ventricular outflow tract dilation or stenting) would help decrease mortality and morbidity compared to a MBTS in suitable children needs to be established with prospective studies …”
Section: Discussionmentioning
confidence: 99%
“…[1][2][3][4] Recently, two studies comparing surgical BTS to PDA stenting with adjusted analyses to balance the cohorts found that infants palliated with a PDA stent had favorable outcomes. 5,6 PDA stenting was associated with lower mortality and reduced hospital length of stay, albeit with equivalent or higher rates of reintervention.…”
mentioning
confidence: 89%