Comparison between phenotype and molecular resistance characteristic in Staphylococcus epidermidis isolates from wound infections in Al-Basrah province, Iraq

Al-Amara, Saad S. Mahdi

doi:10.21533/pen.v9i2.1943

Cited by 1 publication

(1 citation statement)

References 19 publications

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“…One study [ 41 ] isolated and identified 12 strains of S. epidermidis from 150 smear samples and tracked the blaZ and mecA genes in 91.7% of the studied samples; in addition to these genes, this same author investigated the presence of other genes that appeared with lesser incidence and 75% of the samples were resistant to penicillin and 66.7% to oxacillin.…”

Section: Discussionmentioning

confidence: 99%

Staphylococcus spp. Causatives of Infections and Carrier of blaZ, femA, and mecA Genes Associated with Resistance

et al. 2023

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Staphylococcus spp. have been associated with cases of healthcare associated infections due to their high incidence in isolates from the hospital environment and their ability to cause infections in immunocompromised patients; synthesize biofilms on medical instruments, in the case of negative coagulase species; and change in genetic material, thus making it possible to disseminate genes that code for the acquisition of resistance mechanisms against the action of antibiotics. This study evaluated the presence of blaZ, femA, and mecA chromosomal and plasmid genes of Staphylococcus spp. using the qPCR technique. The results were associated with the phenotypic expression of resistance to oxacillin and penicillin G. We found that the chromosomal femA gene was present in a greater proportion in S. intermedius when compared with the other species analyzed, while the plasmid-borne mecA gene was prevalent in the S. aureus samples. The binary logistic regression performed to verify the association among the expression of the genes analyzed and the acquisition of resistance to oxacillin and penicillin G were not significant in any of the analyses, p > 0.05.

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Section: Discussionmentioning

confidence: 99%