Comparison between PRP vs iPRF as an adjunct therapy in Infra-bony Pocket treatment

Amin, Amal; Elkady, Mostafa; destawy, mahmoud el

doi:10.21608/ajdsm.2022.121791.1311

Cited by 5 publications

(2 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…CAL and PPD were investigated in all i-PRF studies [ 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ]. Each showed reductions in pocket depth and improvements in CAL rates.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Platelet-Rich Plasma (PRP) and Injectable Platelet-Rich Fibrin (i-PRF) in the Non-Surgical Treatment of Periodontitis—A Systematic Review

Niemczyk,

Janik,

Żurek

et al. 2024

IJMS

View full text Add to dashboard Cite

The gold standard in the non-surgical treatment of periodontitis is scaling and root planing (SRP). In recent years, the use of autogenous platelet concentrates has spread over many specialties in dentistry and, thus, has also been gaining popularity in periodontal treatment. Its two main fractions are platelet-rich plasma (PRP) and platelet-rich fibrin (PRF), which, since 2014, can also be used via injection as injectable platelet-rich fibrin (i-PRF). The authors conducted a comprehensive systematic review in accordance with the PRISMA 2020 guidelines. It involved searching PubMed, Embase, Scopus, and Google Scholar databases using the phrases (“Root Planing” OR “Subgingival Curettage” OR “Periodontal Debridement”) AND (“Platelet-Rich Plasma”). Based on the authors’ inclusion and exclusion criteria, 12 results were included in the review, out of 1170 total results. The objective of this review was to ascertain the impact of utilizing PRP and i-PRF in SRP. The results revealed that both the incorporation of PRP and i-PRF were found to be significantly associated with are duction in gingival pocket depth and again in clinical attachment level; however, i-PRF demonstrated superiority in improving clinical parameters. Furthermore, i-PRF demonstrated notable bactericidal efficacy against Porphyromonas gingivalis. On the other hand, PRP proved inferior to an Nd:YAG laser in clinical parameter improvement; however, it demonstrated significant efficiency as well. This literature review led the authors to the conclusion that autologous platelet concentrates might be competent agents for improving the therapeutic outcomes of SRP.

show abstract

“…CAL and PPD were investigated in all i-PRF studies [ 42 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 , 53 ]. Each showed reductions in pocket depth and improvements in CAL rates.…”

Section: Resultsmentioning

confidence: 99%

“…Nevertheless, the use of PRP also showed a significant improvement in clinical parameters. The study by Amin et al [ 44 ] was the only study to compare the effects of PRP and i-PRF. In their study, 30 patients underwent SRP in conjunction with PRP, while 30 patients underwent SRP in conjunction with i-PRF.…”

Section: Resultsmentioning

confidence: 99%

Platelet-Rich Plasma (PRP) and Injectable Platelet-Rich Fibrin (i-PRF) in the Non-Surgical Treatment of Periodontitis—A Systematic Review

Niemczyk,

Janik,

Żurek

et al. 2024

IJMS

View full text Add to dashboard Cite

show abstract

Clinical evaluation of the combined efficacy of injectable platelet‐rich fibrin along with scaling and root planing in the non‐surgical periodontal therapy of stage III and grade C periodontitis patients having type 2 diabetes mellitus: A randomized controlled trial

Shunmuga,

Tadepalli,

Parthasarathy

et al. 2023

Clin Adv Periodontics

View full text Add to dashboard Cite

BackgroundThis randomized controlled trial was aimed to evaluate the combined efficacy of injectable platelet‐rich fibrin (i‐PRF) and scaling and root planing (SRP) in type 2 diabetes mellitus subjects having periodontitis.MethodsTwenty‐six Stage III, grade C periodontitis subjects (HbA1c > 7) were recruited in this split‐mouth study. Following SRP, the test sites received subgingival application of i‐PRF, while the control sites received saline. Plaque index, bleeding on probing, modified gingival index, probing pocket depth (PPD) and clinical attachment level (CAL) were measured at baseline, 3 and 6 months.ResultsTwenty‐three participants completed the course of research. The Friedman test followed by Dunn's post hoc test, revealed significant improvement in all the clinical parameters from baseline to 3 and 6 months in both the study groups (p ≤ 0.05). The mean PPD and CAL decreased from 6.30 ± 1.25 and 7.48 ± 1.75 at baseline to 3.48 ± 1.34 and 4.39 ± 1.67 at 6 months in control sites and from 6.57 ± 1.56 and 7.61 ± 1.69 to 3.39 ± 1.23 and 4.26 ± 1.81 at 6 months in test sites (p ≤ 0.0001). Intergroup analysis found no statistical significant differences in the evaluated parameters across all time intervals (p > 0.05)ConclusionThe results indicated that the adjunctive application of i‐PRF to SRP provided similar benefits as saline and SRP in diabetes mellitus subjects.Key Points Question: To find the combined efficacy of injectable platelet‐rich fibrin (i‐PRF) along with scaling and root planing (SRP) in the management of periodontal pockets of Stage III and Grade C periodontitis patients having Type 2 Diabetes Mellitus (T2DM). Finding: All of the treated sites showed satisfactory healing. Both the treatment modalities (i‐PRF + SRP and Saline + SRP) were effective in the treatment of periodontal pockets. At 3 and 6 months, there were no significant differences in periodontal parameters between groups. Meaning: The application of i‐PRF as an adjunct to SRP provided similar benefits as saline and SRP in improving clinical parameters in subjects with stage III and grade C periodontitis patients having T2DM (HbA1C > 7).

show abstract

The effectiveness of autologous platelet-rich concentrates as an adjunct during nonsurgical periodontal therapy: a systematic review and meta-analysis of randomized controlled trials

Nik Eezammuddeen,

Johari,

Demius

et al. 2024

Evid Based Dent

View full text Add to dashboard Cite

Comparison between PRP vs iPRF as an adjunct therapy in Infra-bony Pocket treatment

Cited by 5 publications

References 25 publications

Platelet-Rich Plasma (PRP) and Injectable Platelet-Rich Fibrin (i-PRF) in the Non-Surgical Treatment of Periodontitis—A Systematic Review

Platelet-Rich Plasma (PRP) and Injectable Platelet-Rich Fibrin (i-PRF) in the Non-Surgical Treatment of Periodontitis—A Systematic Review

Clinical evaluation of the combined efficacy of injectable platelet‐rich fibrin along with scaling and root planing in the non‐surgical periodontal therapy of stage III and grade C periodontitis patients having type 2 diabetes mellitus: A randomized controlled trial

The effectiveness of autologous platelet-rich concentrates as an adjunct during nonsurgical periodontal therapy: a systematic review and meta-analysis of randomized controlled trials

Contact Info

Product

Resources

About