Comparison Between Wells’ Criteria and Khorana Score in Detecting Asymptomatic Deep Vein Thrombosis in Colorectal Cancer Patients in Dr. Hasan Sadikin Hospital

Abstract

Background: Deep vein thrombosis is a blood clot that occurs in the deep veins. Fifty percent of patients with deep vein thrombosis do not show clinical symptoms. The incidence of deep vein thrombosis in colorectal cancer patients is higher than in other cancer patients. Several scoring system models, such as Wells’ criteria and Khorana score, were developed to help diagnose deep vein thrombosis . Methods: This study was a prospective observational analytic with cross sectional design that compared the Khorana score with Wells’ criteria in predicting the occurrrence of asymptomatic deep vein thrombosis in colorectal cancer patients. Comparisons were made using Chi Square analytical test and diagnostic tests. Results: A total of 63 patients were obtained. Using Wells’ criteria, 55 patients (87.3%) fell into the mild risk category, 8 patients (12.7%) in the moderate risk category and no patients in the high risk category. Using Khorana score, 35 patients (55.6%) fell into the mild risk category, 28 (44.4%) patients in the moderate risk category, and no high risk category patients were found. There were 14 patients (22.2%) with asymptomatic deep vein thrombosis and 49 patients (77.8%) without deep vein thrombosis. Comparison of the proportion of Wells’ criteria with asymptomatic patients has a p-value of 0.48, while Khorana score with asymptomatic patients has a p-value of 0.001. Conclusion: Khorana score is better than Wells’ criteria in detecting asymptomatic deep vein thrombosis in colorectal cancer patients.