Comparison in bioactivity and characteristics of Ginkgo biloba seed polysaccharides from four extract pathways

Hu, Jialun; Liu, Yue; Li-ming, Cheng; Shi, Ruijie; Qayum, Abdul; Bilawal, Akhunzada; Gantumur, Munkh-Amgalan; Hussain, Muhammad; Jiang, Zhanmei; Tian, Bingbing

doi:10.1016/j.ijbiomac.2020.05.129

Cited by 39 publications

(28 citation statements)

References 40 publications

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“…The surface was irregular with many tiny gaps; at an increased magnification of 20 000 × and 40 000 ×, the branched chain structure of CHP‐2 was basically flocculent, and interconnected relationships were observed, indicating that the polysaccharide molecules repel each other, with weak mutual attraction. [ 37 ]…”

Section: Resultsmentioning

confidence: 99%

Structure of Cardamine hupingshanensis No. 2 Polysaccharide (CHP‐2) and Its Effect on Streptozotocin‐induced Diabetic Rats

Huang

Zhang

et al. 2021

Starch Stärke

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Four new types of water‐soluble polysaccharides are isolated from Cardamine hupingshanensis. Herein, this study examines C. hupingshanensis polysaccharide no. 2 (CHP‐2) with a molecular weight of 21.75 kDa. Analysis revealed that CHP‐2 is composed of d‐glucuronic acid, d‐galacturonic acid, glucose, galactose, and L‐arabinose. It is speculated that the main connecting bond is →4)‐α‐D‐Glc(p)‐(1→), →t)‐α‐D‐Glcp‐(1→). Through perfusion experiments using streptozotocin‐induced diabetic rats, oral CHP‐2 solution is found to significantly reduce food intake, water intake, and fasting blood glucose levels, while increasing the weights of rats. In addition, CHP‐2 significantly reduces the serum and liver malondialdehyde contents and increases the activity of the corresponding antioxidant enzymes. Moreover, the effect elicited by the CHP‐2 solution is similar to that of phenformin hydrochloride solution. Hence, the results of this study suggest that CHP‐2 exhibits blood sugar‐lowering and anti‐oxidation effects.

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Section: Resultsmentioning

confidence: 99%

Structure of Cardamine hupingshanensis No. 2 Polysaccharide (CHP‐2) and Its Effect on Streptozotocin‐induced Diabetic Rats

Huang

Zhang

et al. 2021

Starch Stärke

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“…Due to the fact that the diverse biomass extractives of raw material, e.g., star anise and black pepper, possessed potent therapeutic efficacy, antioxidant, and antimicrobial activities, a number of approaches were introduced previously, such as hot water extraction (Hu et al, 2020), hydro-distillation (Ibrahim et al, 2017), steam-distillation (Nasrollahi et al, 2019), solvent extraction (Chaves et al, 2020), supercritical fluid CO 2 extraction (Patra et al, 2020), and microwave-assisted extraction (Sun et al, 2020), to isolate and extract the bioactive components from these natural resources.…”

Section: Introductionmentioning

confidence: 99%

Multistage Extraction of Star Anise and Black Pepper Derivatives for Antibacterial, Antioxidant, and Anticancer Activity

et al. 2021

Front. Chem.

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Recently, natural resources have attracted considerable interest for their applications in food security and human health problems. Traditional natural spices, such as star anise and black pepper, played important roles in the pharmaceutical and food industries due to their strong pharmacological activity, antioxidant potential and rare complications. In order to achieve biomasses from the natural product with multiple bioactivities, we developed the multistage extraction method to extract and separate various bioactive compounds from these natural plants. Our work demonstrated that various bioactive-rich extractives were achieved using steam distilled- or oxidative-extraction methods with high extraction yields and purity. Furthermore, the extractives in each step can be used not only as bioactive compounds, but also as a resource to further prepare different derivatives during the next extractive step, providing biomass-saving to a great extent. The extractives obtained with high yields and purities (>82%) were identified by 1H NMR, 13C NMR, FTIR, UV-vis, fluorescence spectroscopy, and high-performance liquid chromatography (HPLC). Moreover, these biomasses display potent antibacterial activities against some types of microorganisms such as S.aureus, S.pyogenes, E.coli, and S.typhi with a lowest MIC of 400 μg/ml for the development of antibacterial agents, significant antioxidant activity as the natural antioxidant for enhancing food shelf-life, and excellent anticancer activity that induces significant cancer cell apoptosis. This work showed the different multistage extracts from natural products, which enable them to be applied in the fields of the pharmaceutical industry and the food industry.

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“…The optimized CEUE conditions (24.68 ml/g, 60.52 min, and 61.65°C) were compared with that of traditional HWE, such as Tunisian Zizyphus lotus fruit polysaccharides (39 ml/g, 91.2°C, and 3.25 hr), Chaetomorpha linum polysaccharides (20 ml/g, 90°C, and 4 hr), Ginkgo biloba seed polysaccharides (15 ml/g, 75°C, and 8 hr), etc. (Hammi et al., 2016; Hamzaoui et al., 2020; Hu et al., 2020). It is clear that extraction temperature and time of CEUE are much lower than HWE.…”

Section: Resultsmentioning

confidence: 99%

Optimization of complex enzyme‐ultrasonic synergistic extraction of water‐soluble polysaccharides from Perilla frutescens seed meal: Purification, characterization and in vitro antioxidant activity

Zhang

Reddy

et al. 2021

Food Processing Preservation

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The new feasible complex enzyme‐ultrasonic synergy extraction (CEUE) was optimized by response surface methodology (RSM) for extracting Perilla seed meal polysaccharides (PSMP), the optimum extraction conditions were: compound enzyme dosage (X1) of 6.6%, liquid–solid ratio (X2) of 25 ml/g, extraction time (X3) of 61 min, extraction temperature (X4) of 62°C, the verified yield was 7.711 ± 0.201% at the optimum extraction conditions. The RSM results confirmed that the effects of X1 and X4 on CEUE yield were more significant than X2 and X3. The maximum weight loss rate of PSMP and purified component PSMP‐1 due to degradation of polysaccharides were −4.84%/min (295.33°C) and −8.47%/min (313.67°C) according to thermogravimetry and differential thermogravimetry (TG‐DTG) curves. PSMP and PSMP‐1 were β‐D‐glucopyranose compounds, composed of rhamnose, arabinose, xylose, mannose, glucose, galactose, with relative molar ratios 6.07:40.78:10.91:1.34:1.00:5.12 and 0.69:11.13:5.55:0.90:1.00:4.71. This study determined physicochemical and antioxidant activities properties of Perilla polysaccharides. Practical applications As hot water extraction (HWE) process is a traditional method for polysaccharide extraction, high cost of manipulating with respect to duration and energy consumption limit the promotion of this technology. In this work, the CEUE process optimized by RSM is more suitable for research and development of highly active natural ingredients and is a promising alternative method for HWE of polysaccharides for advantages of high efficiency and energy saving. If the one‐time fixed investment cost of the equipment was put aside, CEUE can effectively decrease subsequent operating costs by reducing the extraction temperature, shortening extraction time, and increasing raw material utilization.

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Comparison in bioactivity and characteristics of Ginkgo biloba seed polysaccharides from four extract pathways

Cited by 39 publications

References 40 publications

Structure of Cardamine hupingshanensis No. 2 Polysaccharide (CHP‐2) and Its Effect on Streptozotocin‐induced Diabetic Rats

Structure of Cardamine hupingshanensis No. 2 Polysaccharide (CHP‐2) and Its Effect on Streptozotocin‐induced Diabetic Rats

Multistage Extraction of Star Anise and Black Pepper Derivatives for Antibacterial, Antioxidant, and Anticancer Activity

Optimization of complex enzyme‐ultrasonic synergistic extraction of water‐soluble polysaccharides from Perilla frutescens seed meal: Purification, characterization and in vitro antioxidant activity

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