Comparison of a Behavioral Versus an Educational Weight Management Intervention After Renal Transplantation: A Randomized Controlled Trial

Schmid-Mohler, Gabriela; Zala, Patrizia; Graf, Nicole; Witschi, Patrick; Mueller, Thomas; Wüthrich, Rudolf P.; Huber, Laura; Fehr, Thomas; Spirig, Rebecca

doi:10.1097/txd.0000000000000936

Cited by 11 publications

(28 citation statements)

References 26 publications

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“…The individual study sample sizes ranged from eight [41] to 452 participants [42]. Two of the four studies include other transplant populations [43,44]; however, one author was able to provide data for the KTR sub-group on request [43].…”

Section: Search Results and Study Characteristicsmentioning

confidence: 99%

“…Six studies reported body weight only [39,41,44,47,48,50], four reported BMI [43,45,49,51], and six reported both body weight and BMI [36,42,43,46,52,53] post-intervention. Seven out of the sixteen studies recorded body weight or BMI at an interim time point of three to six months, and at a one-year follow-up [36,39,45,49,50,52,54].…”

Section: Search Results and Study Characteristicsmentioning

confidence: 99%

“…Methodological variation was evident across the ten RCTs included in this systematic review and meta-analysis. One study included a 12-month diet only intervention [45], three studies [36,39,46] included exercise only interventions ranging from three to twelve months, and six RCTs included combined interventions [43,44,48,49,53,54]. The RCTs with combined interventions varied significantly in duration between fourteen weeks [44], six months [48,53], eight months [43], and one year [49,54].…”

Section: Characteristics Of Interventionsmentioning

confidence: 99%

“…One study included a 12-month diet only intervention [45], three studies [36,39,46] included exercise only interventions ranging from three to twelve months, and six RCTs included combined interventions [43,44,48,49,53,54]. The RCTs with combined interventions varied significantly in duration between fourteen weeks [44], six months [48,53], eight months [43], and one year [49,54]. Two studies [48,54] did not report the specifics of the PA component of the combined intervention.…”

Section: Characteristics Of Interventionsmentioning

confidence: 99%

“…Some were dietitian-led face-to-face visits or telephone calls [45,48,54], one was provided by a physiotherapist [39], two were provided by exercise professionals [46,49], and one RCT did not specify the intervention provider [36]. Two recent RCTs [43,53] included combined interventions with a digital delivery component. Serper et al [44], provided both the two intervention groups with access to a combined online platform.…”

Section: Characteristics Of Interventionsmentioning

confidence: 99%

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Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

Castle

McBride

Greenwood

et al. 2021

Kidney and Dialysis

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Weight gain within the first year of kidney transplantation is associated with adverse outcomes. This narrative systematic review and meta-analysis examines the effect of exercise, physical activity, dietary, and/or combined interventions on body weight and body mass index (BMI) within the first year of kidney transplantation. Seven databases were searched from January 1985 to April 2021 (Prospero ID: CRD42019140865), using a ‘Population, Intervention, Controls, Outcome’ (PICO) framework. The risk-of-bias was assessed by two reviewers. A random-effects meta-analysis was conducted on randomized controlled trials (RCTs) that included post-intervention body weight or BMI values. Of the 1197 articles screened, sixteen met the search criteria. Ten were RCTs, and six were quasi-experimental studies, including a total of 1821 new kidney transplant recipients. The sample sizes ranged from 8 to 452. Interventions (duration and type) were variable. Random-effects meta-analysis revealed no significant difference in post-intervention body weight (−2.5 kg, 95% CI −5.22 to 0.22) or BMI (−0.4 kg/m2, 95% CI −1.33 to 0.54). Despite methodological variance, statistical heterogeneity was not significant. Sensitivity analysis suggests combined interventions warrant further investigation. Five RCTs were classified as ‘high-risk’, one as ‘some-concerns’, and four as ‘low-risk’ for bias. We did not find evidence that dietary, exercise, or combined interventions led to significant changes in body weight or BMI post kidney transplantation. The number and quality of intervention studies are low. Higher quality RCTs are needed to evaluate the immediate and longer-term effects of combined interventions on body weight in new kidney transplant recipients.

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Section: Search Results and Study Characteristicsmentioning

confidence: 99%

Section: Search Results and Study Characteristicsmentioning

confidence: 99%

Section: Characteristics Of Interventionsmentioning

confidence: 99%

Section: Characteristics Of Interventionsmentioning

confidence: 99%

Section: Characteristics Of Interventionsmentioning

confidence: 99%

See 3 more Smart Citations

Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

Castle

McBride

Greenwood

et al. 2021

Kidney and Dialysis

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Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients

Mellon¹,

Doyle²,

Hickey³

et al. 2022

Cochrane Database of Systematic Reviews

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Educational Interventions for Haemodialysis Patients in the Transplant Process: A Systematic Review

Oriol‐Vila,

Rota‐Musoll,

Molina‐Robles

et al. 2024

Nursing Open

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AimTo systematically evaluate empirical studies investigating nursing educational interventions for patients with haemodialysis at the different stages of cadaveric kidney transplantation and synthesise these findings.DesignA systematic review of clinical interventions.MethodsOn clinical trials published in Spanish and English, between January 2005 and July 2022, in the main databases. The number of studies identified is shown in the flowchart of the PRISMA review. For the critical assessment of the scientific quality of the studies, the CASPe checklist and the Cochrane risk of bias assessment tool were applied.ResultsEleven studies were obtained in which nursing educational interventions focused on posttransplantations and one that considered care from the person's admission to hospital were evaluated. The results obtained identified four themes: health education, empowerment, quality of life and holistic patient care with the help of different support methods, including individual and personalised support, group format and informational support via an educational brochure, telephone and website.ConclusionThe reviewed studies suggest that after receiving educational interventions patient dialysis treatment and kidney transplant recipient, have better health outcomes.Patient ContributionLarger studies are needed to promote a comprehensive and continuous self‐care model throughout the kidney transplant process.Implications for Nursing Health EducationNursing educational interventions are necessary throughout the transplantation process for the patient dialysis and the family in a comprehensive and continuous manner. In the future, clinical trial studies are needed at the pretransplantation stage.

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Comparison of a Behavioral Versus an Educational Weight Management Intervention After Renal Transplantation: A Randomized Controlled Trial

Cited by 11 publications

References 26 publications

Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

Interventions for increasing immunosuppressant medication adherence in solid organ transplant recipients

Educational Interventions for Haemodialysis Patients in the Transplant Process: A Systematic Review

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