Comparison of Bone Tissue Elements Between Normal and Osteoarthritic Pelvic Bones in Dogs

Nganvongpanit, Korakot; Buddhachat, Kittisak; Brown, Janine L.

doi:10.1007/s12011-015-0556-4

Cited by 17 publications

(5 citation statements)

References 35 publications

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“…Speculatively, the elemental composition may be not be homogenous in cross-sectional areas of the horn, leading to varied elemental content between layers of keratinized tissue. Indeed, our previous work has shown that elemental distributions can vary across longitudinal and transversal sites of various tooth and bone types [ 3 , 12 , 13 ]. Finally, the difference in results may be related to the specific elements measured in each study.…”

Section: Discussionmentioning

confidence: 99%

Elemental Analysis of Bone, Teeth, Horn and Antler in Different Animal Species Using Non-Invasive Handheld X-Ray Fluorescence

Buddhachat¹,

Klinhom²,

Siengdee³

et al. 2016

PLoS ONE

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Mineralized tissues accumulate elements that play crucial roles in animal health. Although elemental content of bone, blood and teeth of human and some animal species have been characterized, data for many others are lacking, as well as species comparisons. Here we describe the distribution of elements in horn (Bovidae), antler (Cervidae), teeth and bone (humerus) across a number of species determined by handheld X-ray fluorescence (XRF) to better understand differences and potential biological relevance. A difference in elemental profiles between horns and antlers was observed, possibly due to the outer layer of horns being comprised of keratin, whereas antlers are true bone. Species differences in tissue elemental content may be intrinsic, but also related to feeding habits that contribute to mineral accumulation, particularly for toxic heavy metals. One significant finding was a higher level of iron (Fe) in the humerus bone of elephants compared to other species. This may be an adaptation of the hematopoietic system by distributing Fe throughout the bone rather than the marrow, as elephant humerus lacks a marrow cavity. We also conducted discriminant analysis and found XRF was capable of distinguishing samples from different species, with humerus bone being the best source for species discrimination. For example, we found a 79.2% correct prediction and success rate of 80% for classification between human and non-human humerus bone. These findings show that handheld XRF can serve as an effective tool for the biological study of elemental composition in mineralized tissue samples and may have a forensic application.

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Section: Discussionmentioning

confidence: 99%

Elemental Analysis of Bone, Teeth, Horn and Antler in Different Animal Species Using Non-Invasive Handheld X-Ray Fluorescence

Buddhachat¹,

Klinhom²,

Siengdee³

et al. 2016

PLoS ONE

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“…This study analyzed 45 os coxae bones and these were categorized as normal, mild grade OA, moderate grade OA, and severe grade OA. The findings of this study suggest that these two elements may be useful in future studies on the etiology and pathophysiology of OA (Nganvongpanit et al 2016b).…”

Section: Elemental Studymentioning

confidence: 84%

A lesson from our institute; Why do veterinary schools need an anatomy museum?

Kongtueng¹,

Yotanyamaneewong²

2021

VIS

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Anatomy has always been a key discipline in the field of veterinary medicine, as this fundamental scientific discipline offers vital foundational knowledge on how the structure of an organ relates to its function and health. It demonstrates how the three-dimensional structure of an organism relates to the physical diagnosis of a disease, as well as to help shed light on how surgical and medical approaches can be employed to treat various diseases. This review provides supportive evidence on the importance and usefulness of the anatomy museum located within our veterinary institute. Furthermore, our outcomes will encourage all veterinary schools to consider having their own on-site anatomy museum. From our experience, the practical usefulness of an anatomy museum can be divided into 4 categories that include the study of anatomy, the study of histology, elemental study, and social education. The samples housed in an anatomy museum can increase the publishing potential of all staff members of the parent institute, as well as to elevate the reputation and general recognition of the institute. Moreover, an anatomy museum can facilitate out-of-class learning opportunities for non-university educational facilities such as kindergartens, and primary or secondary schools.

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“…Moreover, the observations of Nganvongpanit et al showed a higher iron concentration in the synovial fluid in the degenerated knee joints. The decrease in the iron concentration, along with the advancement of the degenerative changes, may be one of the reasons for the loss of flexibility in the intervertebral disc, due to the reduction in the biosynthesis of collagen fibers and elastin, for which the iron ions are necessary [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

Changes in Elements and Relationships among Elements in Intervertebral Disc Degeneration

Staszkiewicz

Bryś²,

Gładysz

et al. 2022

IJERPH

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Intervertebral disc degeneration (IVDD) is a complex and progressive process of disc aging. One of the most important causes of changes in the internal environment, leading to IVDD, can be changes in the concentration of individual metal elements. This study aimed to analyze the concentrations of copper, iron, manganese, lead, zinc, sodium, potassium, phosphorus, and calcium in the degenerated intervertebral discs of the lumbosacral spine, compared to healthy intervertebral discs. The study group (S) consisted of 113 Caucasian patients, qualified by a specialist surgeon for IVDD of the lumbosacral spine. The control group (C) consisted of 81 individuals. The biological material was obtained from Caucasian human cadavers during post-mortem examination. The concentrations of individual elements were assessed using inductively coupled plasma–optical emission spectroscopy (ICP-OES). Statistically significant differences in the concentrations of microelements, depending on the degree of pain intensity, were noted for only potassium (p < 0.05). Statistically significant differences in the concentrations of the assessed microelements, depending on the degree of radiological advancement of the lesions, were noted for copper and iron (p < 0.05). In the degenerated intervertebral discs, the strongest relationships were noted between the concentrations of zinc and lead (r = 0.67; p < 0.05), zinc and phosphorus (r = 0.74; p < 0.05), and zinc and calcium (r = 0.77; p < 0.05). It has been indicated that, above all, the concentrations of copper and iron depend on the advancement of radiological changes, according to the Pfirrmann scale; however, no influence on the pain intensity, depending on the concentration of the assessed elements, was found.

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Comparison of Bone Tissue Elements Between Normal and Osteoarthritic Pelvic Bones in Dogs

Cited by 17 publications

References 35 publications

Elemental Analysis of Bone, Teeth, Horn and Antler in Different Animal Species Using Non-Invasive Handheld X-Ray Fluorescence

Elemental Analysis of Bone, Teeth, Horn and Antler in Different Animal Species Using Non-Invasive Handheld X-Ray Fluorescence

A lesson from our institute; Why do veterinary schools need an anatomy museum?

Changes in Elements and Relationships among Elements in Intervertebral Disc Degeneration

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