Comparison of different activity parameters in atopic dermatitis: correlation with clinical scores

Abstract

Our data indicate that basic clinical scoring remains a most effective and relevant method of recording skin disease activity in AD.

Urinary biomarker of oxidative stress in patients with psoriasis vulgaris and atopic dermatitis

“…13 Interestingly, low levels of single urinary nitrate have been reported in cases of childhood atopic dermatitis. 14 We are uncertain about these discrepancies at this stage. However, not only measurements in larger group of patients but also newly devised methods may be necessary to determine the role of NO in atopic dermatitis by taking urine sample.…”

Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell–attracting chemokine (CTACK) levels in allergic diseasesTARC and CTACK are disease-specific markers for atopic dermatitis

“…A large variety of laboratory 24 and clinical measurements 25 have been linked to disease severity in AD, which reflects the difficulties in defining a selective and objective marker that best relates to disease severity. This has led to a wide variation in outcome measurements in clinical studies that is hindering evidencebased practice.…”

Role of vasculature in atopic dermatitis

“…Soluble E-selectin appears to be the best serologic marker to determine disease activity in AD thus far. 18 Plasma concentration of soluble E-selectin is a reliable marker of disease activity on treatment with cyclosporin A.…”