Comparison of Diffusion Tensor Tractography and Motor Evoked Potentials for the Estimation of Clinical Status in Subacute Stroke

Chun, Kwang-Soo; Lee, Yong Taek; Park, Jong-Wan; Lee, Joon-Youn; Park, Chul-Hyun; Yoon, Kyung Jae

doi:10.5535/arm.2016.40.1.126

Cited by 4 publications

(4 citation statements)

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“…AMP can effectively predict the prognosis of patients with acute stroke ( 31 ). After onset of acute stroke, a higher amplitude in AMP is a reliable indicator of improved motor recovery and functional outcomes ( 32 ). Moreover, motor recovery is closely related to an improvement in corticospinal tract conduction, and a shortened CMCT indicates predominant motor recovery ( 33 ).…”

Section: Discussionmentioning

confidence: 99%

Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

Meng

Meng²,

Tan

et al. 2018

Front. Neurol.

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BackgroundRehabilitation training during the acute phase of stroke (<48 h) markedly improves impaired upper-limb movement. Hand-arm bimanual intensive training (HABIT) represents an intervention that promotes improvements in upper extremity function in children with cerebral palsy. This study repurposed HABIT in acute stroke patients and assessed recovery of upper extremity function when compared with a conventional rehabilitation program (CRP).MethodsIn a randomized trial, 128 patients with acute stroke were assigned to the HABIT or the CRP groups. The primary endpoint was clinical motor functional assessment that was guided by the Fugl-Meyer motor assessment (FMA) and outcomes of the action research arm test (ARAT). The secondary endpoint was an improved neurophysiological evaluation according to the motor-evoked potential amplitude (AMP), resting motion threshold (RMT), and central motor conduction time (CMCT) scores over the 2-week course of therapy. In both groups, scores were evaluated at baseline, 1 week from commencing therapy, and post-therapy.ResultsAfter 2 weeks, the HABIT group showed improved scores as compared the CRP group for FMA (51.7 ± 6.44 vs. 43.5 ± 5.6, P < 0.001), ARAT (34.5 ± 6.2 vs. 33.3 ± 6.3, P = 0.022), and AMP (1.1 ± 0.1 vs. 1.0 ± 0.1, P < 0.001). However, CMCT (8.6 ± 1.0 vs. 9.1 ± 0.6, P = 0.054) and RMT (55.3 ± 4.2 vs. 57.5 ± 4.1, P = 0.088) were similar when comparing between groups.ConclusionHABIT significantly improved motor functional and neuro-physiological outcomes in patients with acute stroke, which suggested that HABIT might represent an improved therapeutic strategy as compared CRP.

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Section: Discussionmentioning

confidence: 99%

Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

Meng

Meng²,

Tan

et al. 2018

Front. Neurol.

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“…Dynamic stabilization was automatically implemented to enhance image consistency and to ameliorate signal drift [ 44 ]. A diffusion registration package was applied during acquisition in order to reduce geometrical distortions caused by eddy current induced artefacts [ 35 , 45 , 46 ].…”

Section: Methodsmentioning

confidence: 99%

The role of diffusion tensor imaging as an objective tool for the assessment of motor function recovery after paraplegia in a naturally-occurring large animal model of spinal cord injury

et al. 2018

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BackgroundTraumatic spinal cord injury (SCI) results in sensory and motor function impairment and may cause a substantial social and economic burden. For the implementation of novel treatment strategies, parallel development of objective tools evaluating spinal cord (SC) integrity during motor function recovery (MFR) is needed. Diffusion tensor imaging (DTI) enables in vivo microstructural assessment of SCI.MethodsIn the current study, temporal evolvement of DTI metrics during MFR were examined; therefore, values of fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured in a population of 17 paraplegic dogs with naturally-occurring acute SCI showing MFR within 4 weeks after surgical decompression and compared to 6 control dogs. MRI scans were performed preoperatively and 12 weeks after MFR was observed. DTI metrics were obtained at the lesion epicentre and one SC segment cranially and caudally. Variance analyses were performed to compare values between evaluated localizations in affected dogs and controls and between time points. Correlations between DTI metrics and clinical scores at follow-up examinations were assessed.ResultsBefore surgery, FA values at epicentres were higher than caudally (p = 0.0014) and control values (p = 0.0097); ADC values were lower in the epicentre compared to control values (p = 0.0035) and perilesional (p = 0.0448 cranially and p = 0.0433 caudally). In follow-up examinations, no significant differences could be found between DTI values from dogs showing MFR and control dogs. Lower ADC values at epicentres correlated with neurological deficits at follow-up examinations (r = − 0.705; p = 0.0023).ConclusionsFindings suggest that a tendency to the return of DTI values to the physiological situation after surgical decompression accompanies MFR after SCI in paraplegic dogs. DTI may represent a useful and objective clinical tool for follow-up studies examining in vivo SC recovery in treatment studies.Electronic supplementary materialThe online version of this article (10.1186/s12967-018-1630-4) contains supplementary material, which is available to authorized users.

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“…[28] A high ranking amplitude in AMP after an acute stroke is a reliable indicator of advanced motor rehabilitation and effective outcome. [29] Furthermore, improved corticospinal tract conduction is linked to motor recovery, and a shorter CMCT suggests prevalent motor recovery. [30] As a result, ARAT, FMA, RMT, AMP, and CMCT were utilised in this research to evaluate therapy efficacy after HABIT and CRP with the goal of discovering a better method.…”

Section: Comparison Of Rehabilitationmentioning

confidence: 99%

Short-term effectiveness of trunk and bimanual hand training on upper limb motor recovery and function in stroke patients

Sahu

Gugnani

Ahluwalia

2022

ijhs

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Background: Stroke is a leading cause of motor impairment in adults and the elderly, necessitating appropriate therapies that might aid upper-limb rehabilitation. Upper-limb rehabilitation is difficult limiting the anticipatory core action using trunk-restraints could be an important factor to consider during Physiotherapy for stroke individuals with upper-arm disability. Different approaches, such as the use of exergames in motor rehabilitation and balance, are being used because they work as motivators, making therapy more enjoyable. Aim: To assess the effects of trunk-restraint reach-to-grasp therapy on trunk arm control following a stroke. The goal of this research was to see how trunk and bimanual hand training affected patients' balance and upper-limb motor function following a stroke. Method: In this work, an experimental design was employed on a randomised control group of 62 stroke patients selected by simple randomization. The research was carried out from September 2020, to august 2021. The Fugl-Meyer Upper Extremity (FMUE) Scale, Modified Ashworth Scale, and the interviewing questionnaire were all employed in this investigation. Results: For the study and control groups, most of the groups that were examined (95.0 percent and 90.0 percent, respectively) had an ischemic stroke.

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Comparison of Diffusion Tensor Tractography and Motor Evoked Potentials for the Estimation of Clinical Status in Subacute Stroke

Cited by 4 publications

References 36 publications

Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

Short-term Efficacy of Hand-Arm Bimanual Intensive Training on Upper Arm Function in Acute Stroke Patients: A Randomized Controlled Trial

The role of diffusion tensor imaging as an objective tool for the assessment of motor function recovery after paraplegia in a naturally-occurring large animal model of spinal cord injury

Short-term effectiveness of trunk and bimanual hand training on upper limb motor recovery and function in stroke patients

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