Comparison of four different treatment strategies in teeth with molar‐incisor hypomineralization‐related enamel breakdown–A retrospective cohort study

Linner, Thomas; Khazaei, Yeganeh; Bücher, Katharina; Pfisterer, Jan; Hickel, Reinhard; Kühnisch, Jan

doi:10.1111/ipd.12636

Cited by 41 publications

(60 citation statements)

References 30 publications

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“…Laboratory manufactured indirect restorations have been studied more recently for MIH-affected molars. Like PMCs, these have reported very high success rates and can also be used in cases where multiple surfaces or cusps are involved and direct restorations would be inappropriate (Gaardmand et al 2013;Dhareula et al 2018Dhareula et al , 2019Linner et al 2020). Three main categories of these restorations have been reported: metal alloys, indirect composite and ceramic restorations.…”

Section: Considerations Affecting Treatment In Severe Casesmentioning

confidence: 99%

Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document

Lygidakis

Garot

Somani

et al. 2021

Eur Arch Paediatr Dent

183

192

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Aim To update the existing European Academy of Paediatric Dentistry (EAPD) 2010 policy document on the ‘Best Clinical Practice guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH).’ Methods Experts, assigned the EAPD, worked on two different topics: (A) Aetiological factors involved in MIH, and (B) Treatment options for the clinical management of MIH. The group prepared two detailed systematic reviews of the existing literature relevant to the topics and following a consensus process produced the updated EAPD policy document on the ‘Best Clinical Practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH).’ The GRADE system was used to assess the quality of evidence regarding aetiology and treatment which was judged as HIGH, MODERATE, LOW or VERY LOW, while the GRADE criteria were used to indicate the strength of recommendation regarding treatment options as STRONG or WEAK/CONDITIONAL. Results (A) Regarding aetiology, it is confirmed that MIH has a multifactorial aetiology with the duration, strength and timing of occurrence of the aetiological factors being responsible for the variable clinical characteristics of the defect. Perinatal hypoxia, prematurity and other hypoxia related perinatal problems, including caesarean section, appear to increase the risk of having MIH, while certain infant and childhood illnesses are also linked with MIH. In addition, genetic predisposition and the role of epigenetic influences are becoming clearer following twin studies and genome and single-nucleotide polymorphisms analyses in patients and families. Missing genetic information might be the final key to truly understand MIH aetiology. (B) Regarding treatment options, composite restorations, preformed metal crowns and laboratory indirect restorations provide high success rates for the posterior teeth in appropriate cases, while scheduled extractions provide an established alternative option in severe cases. There is great need for further clinical and laboratory studies evaluating new materials and non-invasive/micro-invasive techniques for anterior teeth, especially when aesthetic and oral health related quality of life (OHRQoL) issues are concerned. Conclusions MIH has been studied more extensively in the last decade. Its aetiology follows the multifactorial model, involving systemic medical and genetic factors. Further focused laboratory research and prospective clinical studies are needed to elucidate any additional factors and refine the model. Successful preventive and treatment options have been studied and established. The appropriate choice depends on the severity of the defects and the age of the patient. EAPD encourages the use of all available treatment options, whilst in severe cases, scheduled extractions should be considered.

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Section: Considerations Affecting Treatment In Severe Casesmentioning

confidence: 99%

Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document

Lygidakis

Garot

Somani

et al. 2021

Eur Arch Paediatr Dent

183

192

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“…A more recent Swedish study reported unsatisfactory space closure in 26% of the cases (Jalevik, Moller 2007). Some dentists are reluctant to extract permanent teeth and advocate restorative and endodontic treatment and it is nearly always possible to save an FPM when the root is not affected (Linner et al 2020;Bekes 2020). However, our main argument to extract is the lifetime burden of cost and effort for the individual that has to be considered when treatment decisions are made.…”

Section: Discussionmentioning

confidence: 99%

Extraction of first permanent molars severely affected by molar incisor hypomineralisation: a retrospective audit

Brusevold

Kleivene

Grimsøen

et al. 2021

Eur Arch Paediatr Dent

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Aim The aim of this study was to evaluate possible spontaneous space closure after extraction of first permanent molars in children and their eventual need for orthodontic treatment. Methods Twenty-seven children with at least one first permanent molar planned for extraction were enrolled in the study. The children were referred to the Department of Paediatric Dentistry, University of Oslo, between 2009 and 2017. All extracted teeth were severely affected by Molar Incisor Hypomineralisation and/or caries. The children and their parents had consented to extraction and follow-up. Data were analysed with SPSS 26. Results The age of the children was between 5.5 and 12.1 years (mean 8.7) at extraction. The mean follow-up time was 3.2 years (range 1.1–6.3). Sixteen children (59.3%) had all four molars extracted, five (18.5%) had three, five had two and one had one molar extracted. In the maxilla, the second permanent molar had erupted in the place of the first molar in all the children, and none of them needed orthodontic space closure. In the mandible, eight children (29.6%) needed orthodontic treatment to close the spaces after extraction. In three children, the second molar was not yet erupted and treatment need was not settled. Conclusion Extraction of severely affected first permanent molars before the eruption of the second molar is a treatment option causing little additional treatment in the majority of cases.

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“…Daher kann einerseits argumentiert werden, dass restaurative Bedarfe bei MIH-Kindern nicht den Regelfall repräsentie-ren. Andererseits darf auch nicht außer Acht gelassen werden, dass gerade diese Kinder aufgrund von umfangreichen Zahnhartsubstanzdefekten, schmerzhaften Hypersensitivitäten, wiederholten Therapiebedarfen und/oder Kooperationseinschränkungen eine besondere Herausforderung in der täglichen Praxis des Zahnarztes darstellen [18][19][20][21][22].…”

Section: Häufigkeit Und Klinische Ausprägung Der Mihunclassified

Molaren-Inzisiven-Hypomineralisation (MIH). Häufigkeit und mögliche Ursachen unter besonderer Berücksichtigung der Ergebnisse aus den Münchner Geburtskohorten GINIplus und LISA

Kühnisch

Standl

Hickel

et al. 2021

Bundesgesundheitsbl

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ZusammenfassungDie Molaren-Inzisiven-Hypomineralisation (MIH) – mittlerweile auch bekannt unter dem Begriff der Kreidezähne – stellt heute neben der Karies eine häufige Erkrankung der Zähne im Kindes- und Jugendalter dar. Neben den ästhetischen Einschränkungen insbesondere an den Frontzähnen sind Hypersensibilitäten und Schmelzeinbrüche an bleibenden Molaren für die Betroffenen von funktioneller Bedeutung. Während die Häufigkeit der MIH in einer Größenordnung zwischen ~ 10 % und ~ 30 % liegt und gut beschrieben ist, stellt sich die Situation bezüglich der Ursachenforschung unbefriedigend dar. Obwohl in der Vergangenheit Anstrengungen zur Klärung der Ätiologie unternommen wurden, liegt bis in die Gegenwart keine plausible Ätiologiekette vor. Ursachenforschungen sind dabei als methodisch anspruchsvoll zu beurteilen, da diese optimalerweise in prospektiv geplante Geburtskohortenstudien eingebettet sein sollten, welche spätestens mit der Geburt beginnen. Ziel des vorliegenden Beitrages ist es, die klinische Charakteristik der MIH, Häufigkeiten und potenzielle Ursachen unter besonderer Berücksichtigung bereits publizierter Ergebnisse aus den beiden Münchner Geburtskohortenstudien GINIplus und LISA zusammenfassend darzustellen.

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Comparison of four different treatment strategies in teeth with molar‐incisor hypomineralization‐related enamel breakdown–A retrospective cohort study

Cited by 41 publications

References 30 publications

Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document

Best clinical practice guidance for clinicians dealing with children presenting with molar-incisor-hypomineralisation (MIH): an updated European Academy of Paediatric Dentistry policy document

Extraction of first permanent molars severely affected by molar incisor hypomineralisation: a retrospective audit

Molaren-Inzisiven-Hypomineralisation (MIH). Häufigkeit und mögliche Ursachen unter besonderer Berücksichtigung der Ergebnisse aus den Münchner Geburtskohorten GINIplus und LISA

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