2023
DOI: 10.3390/jcm12031007
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Comparison of Hemodynamic Response between Patients with Systolic Heart Failure Differing in Serum Aldosterone Concentrations during and after a 6-Minute Walk Test

Abstract: Aldosterone regulates hemodynamics, including blood pressure (BP), and is involved in the development and progression of cardiovascular diseases, including systolic heart failure (HF). While exercise intolerance is typical for HF, neither BP nor heart rate (HR) have specific characteristics in HF patients. This study compares BP and HR profiles during and after standardized exercise between patients with systolic HF with either lower or higher aldosterone concentrations. We measured BP and HR in 306 ambulatory… Show more

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“…We present maximal and sub-maximal indices of cardiopulmonary fitness, all indicating impairments in performance and cardiopulmonary fitness. O2 pulse was lower in cases than controls in line with prior findings [33,34]. A low O2 pulse can indicate impaired augmentation of stroke volume or impaired peripheral oxygen extraction during exercise.…”
Section: Discussionsupporting
confidence: 89%
“…We present maximal and sub-maximal indices of cardiopulmonary fitness, all indicating impairments in performance and cardiopulmonary fitness. O2 pulse was lower in cases than controls in line with prior findings [33,34]. A low O2 pulse can indicate impaired augmentation of stroke volume or impaired peripheral oxygen extraction during exercise.…”
Section: Discussionsupporting
confidence: 89%