Comparison of medication errors in an American and a British hospital

Dean, Bonnie S.; Allan, Elizabeth Louise; Barber, Nicholas; Barker, Kenneth N.

doi:10.1093/ajhp/52.22.2543

Cited by 118 publications

(92 citation statements)

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“…It has also been demonstrated that such observation did not affect the error rate significantly [17]. In addition, due to ethical reasons, intervention by the researcher to prevent some of the errors from reaching the patients was allowed, as was done in other studies [11,18,42]. However, Dean and Barber [17] found that the researcher's intervention to prevent errors from reaching the patient did not have any significant effect on the error rate.…”

Section: Methodsmentioning

confidence: 97%

Drug administration errors in paediatric wards: a direct observation approach

2009

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Paediatric patients are more vulnerable to drug administration errors due to a lack of appropriate drug dosages and strengths for use in this group of patients. Therefore, the aim of the present study was to determine the extent and types of drug administration errors in two paediatric wards and to identify measures to reduce such errors. A researcher was stationed in two paediatric wards of a teaching hospital to observe all drugs administered to paediatric inpatients in each of the ward, for 1 day in a week over ten consecutive weeks. All data were recorded in a data collection form and then compared with the actual drugs and dosages prescribed for the patients. Of the 857 drug administrations observed, 100 doses had errors, and this gave an error rate of 11.7% [95% confidence interval (CI) 9.5-13.9%]. If wrong time administration errors were excluded, the error rate reduced to 7.8% (95% CI 6.0-9.6%). The most common types of drug administration errors were incorrect time of administration (28.8%), followed by incorrect drug preparation (26%), omission errors (16.3%) and incorrect dose (11.5%). None of the errors observed were considered as potentially life threatening, although 40.4% could possibly cause patient harm. Drug administration errors are as common in paediatric wards in Malaysia as in other countries. Double-checking should be conducted, as this could reduce drug administration errors by about 20%, but collaborative efforts between all healthcare professionals are essential.

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Section: Methodsmentioning

confidence: 97%

Drug administration errors in paediatric wards: a direct observation approach

2009

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“…[3][4][5][6][7] Errors may occur as a result of inaccurate prescribing or failing to consider drug interactions, 8,9 dispensing, preparation of the final drug solution, drug labelling immediately before administration or drug administration with underdosing or overdosing. [10][11][12] Five percentage of drug errors have been classified as serious and 43% as moderately severe. 13 Drug errors in relation to anaesthesia were observed in one of 880 anaesthetic procedures in one study 13 and in one of 133 in another; 3 44.4% 13 up to 70.4% 7 were related to accidental syringe swapping and 46.8% to misidentification of the label.…”

Section: Introductionmentioning

confidence: 99%

A survey of standardised drug syringe label use in European anaesthesiology departments

Wickboldt¹,

Balzer²,

Goncerut³

et al. 2012

European Journal of Anaesthesiology

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“…In-hospital studies have shown that drug administration errors are relatively common, with 3-8% of non-intravenous drug administrations involving at least one error, omission of the administration accounting for roughly half of this figure [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

A technical note concerning non-adherence to drug therapy: exact expressions for the mean and variance of drug concentration

Gallivan

Pagel

Utley

et al. 2008

Health Care Manage Sci

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There is considerable evidence that prescribed drugs are not taken as intended. We present a stochastic pharmacokinetic mathematical model that can be used to assess the implications of non-adherence to prescribed drug regimens, on the part of either patients or health professionals. In the context of an orally administered drug, explicit equations are derived for the time varying mean and variance of the concentration of the drug in the serum, depending on the probability of each scheduled administration being omitted. The analysis presented here can be used to assess whether a given level of non-adherence is likely to have a clinical impact. The methods used can easily be adapted for use in the context of other routes of drug administration.

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Comparison of medication errors in an American and a British hospital

Cited by 118 publications

References 0 publications

Drug administration errors in paediatric wards: a direct observation approach

Drug administration errors in paediatric wards: a direct observation approach

A survey of standardised drug syringe label use in European anaesthesiology departments

A technical note concerning non-adherence to drug therapy: exact expressions for the mean and variance of drug concentration

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