Comparison of methods for baseline determining of fluorescent detector signals of genetic analyzer

Abstract

In article of the methods for baseline determining of signals from a fluorescent detector of a genetic analyzer are discussed. The simulated for signal which has characteristics identical to the characteristics of a real signal is performed. The comparison of the methods to the criterion of mean square error and calculation speed for model signals is done. A qualitative analysis of the effectiveness of methods on real signals is carried out. The theoretical calculations by these methods and research results are presented.