Comparison of methods: Passing and Bablok regression

Bilić-Zulle, Lidija

doi:10.11613/bm.2011.010

Cited by 236 publications

(172 citation statements)

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“…The results of the Passing and Bablok procedure were supplemented with a Bland–Altman plot. The Bland–Altman plot is a graphical method to compare two measurement techniques 7. The level of significance was accepted as P <0.05.…”

Section: Methodsmentioning

confidence: 99%

Low perfusion index affects the difference in glucose level between capillary and venous blood

Acar

Özçelik

Çevik

et al. 2014

TCRM

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AimIn emergency cases, finger stick testing is primarily used to check the blood glucose value of patients since it takes longer to obtain the venous value. In critical patients, under conditions that cause an increase in metabolic state and level of stress, there occurs considerable difference in glucose levels between capillary and venous measurements. This study aimed to investigate the comparability of capillary and venous glucose values, according to the perfusion index level obtained with the Masimo Radical-7® device, in critical patients aged 18 years and over.MethodWe conducted this prospective and observational study in the emergency department of the Eskisehir Osmangazi University hospital between November 3, 2008 and February 2, 2009.ResultsThe blood glucose of 300 critical patients was checked by finger stick in the emergency unit. The participants with normal vital signs had perfusion index between 0 and 5; the results obtained by the two methods were more consistent for perfusion index values of 6 and over. The results were most consistent in aged participants with normal vital sign findings and low perfusion index and in young patients with high perfusion index. In the cases where at least one of the vital signs was abnormal, the glucose values obtained by the two methods were more consistent when the perfusion index was 6 or over. In this group, independently from the perfusion index value, the consistency was higher in younger patients compared with aged patients.ConclusionIn the emergency department, perfusion index value measured by Masimo Radical-7 and capillary blood glucose levels can serve in blood sugar management in critically ill patients.

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Section: Methodsmentioning

confidence: 99%

Low perfusion index affects the difference in glucose level between capillary and venous blood

Acar

Özçelik

Çevik

et al. 2014

TCRM

View full text Add to dashboard Cite

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“…Compared with the other frequently proposed method, the Deming regression ( 4 ), the Passing and Bablok regression could be preferred for comparing clinical methods, because it does not assume measurement error is normally distributed, and is robust against outliers. However, it needs the residuals analysis, the distribution of difference around fitted regression line, for a complete interpretation of regression results ( 5 ). This is quite similar, but more complicated than the analysis of differences, described below.…”

Section: Correlation and Linear Regressionmentioning

confidence: 99%

Understanding Bland Altman analysis

2015

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In a contemporary clinical laboratory it is very common to have to assess the agreement between two quantitative methods of measurement. The correct statistical approach to assess this degree of agreement is not obvious. Correlation and regression studies are frequently proposed. However, correlation studies the relationship between one variable and another, not the differences, and it is not recommended as a method for assessing the comparability between methods. In 1983 Altman and Bland (B&A) proposed an alternative analysis, based on the quantification of the agreement between two quantitative measurements by studying the mean difference and constructing limits of agreement. The B&A plot analysis is a simple way to evaluate a bias between the mean differences, and to estimate an agreement interval, within which 95% of the differences of the second method, compared to the first one, fall. Data can be analyzed both as unit differences plot and as percentage differences plot. The B&A plot method only defines the intervals of agreements, it does not say whether those limits are acceptable or not. Acceptable limits must be defined a priori, based on clinical necessity, biological considerations or other goals. The aim of this article is to provide guidance on the use and interpretation of Bland Altman analysis in method comparison studies.

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“…To evaluate the effects of recentrifugation on positive results near the positive cut-off concentration, we focused our analysis only on concentrations lower than the 50th percentile within our study sample of 189 specimens (first determination, <190 ng/L; 94 specimens). Nonparametric Passing-Bablok regression analysis 16,17 showed that after recentrifugation, a median reduction of 10 ng/L (95% confidence interval [CI], -37.5 --10.0 ng/L) in troponin I concentrations was observed ( Figure 1). A difference plot for the paired data appear in Figure 2.…”

Section: Resultsmentioning

confidence: 99%