Comparison of morphometric, structural, mechanical, and physiologic characteristics of human superficial femoral and popliteal arteries

Jadidi, Majid; Razian, Sayed Ahmadreza; Anttila, Eric; Doan, Tyler; Adamson, Josiah; Pipinos, Margarita; Kamenskiy, Alexey

doi:10.1016/j.actbio.2020.11.025

Cited by 18 publications

(6 citation statements)

References 87 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 4 , 5 , 21 As a lower-limb vessel, the popliteal artery is highly susceptible to decreases in blood flow and subsequent shear stress that accompanies bouts of sedentary activity. 16 , 22 , 23 Restaino et al 24 reported that sitting-induced popliteal endothelial dysfunction is mediated by a reduction in local shear stress which explains how habitual prolonged bouts of sedentary time may attenuate FMD responses. Specifically, habitual exposure of the popliteal artery to reduced local shear stress during prolonged sedentary bouts creates a pro-atherosclerotic environment that promotes endothelial dysfunction and increases the risk of atherosclerosis.…”

Section: Discussionmentioning

confidence: 99%

Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults

et al. 2022

View full text Add to dashboard Cite

Introduction: Acute, laboratory-based bouts of prolonged sitting attenuate lower-limb arterial endothelial-dependent vasodilation. However, the impact of habitual sedentary patterns on popliteal artery endothelial health is unclear. We tested the hypothesis that greater habitual total sedentary time, more time spent in prolonged sedentary bouts, and fewer sedentary breaks would be associated with worse popliteal flow-mediated dilation (FMD) responses. Methods: This cross-sectional study used 98 healthy participants (19–77 years, 53 females) that wore an activPAL monitor on the thigh for 6.4 ± 0.8 days to objectively measure sedentary activity and completed a popliteal ultrasound assessment to determine FMD. Both relative (%baseline diameter) and absolute (mm) FMD were calculated. Using bivariate correlation and multiple regression analyses, we examined if there were relationships between sedentary outcomes and FMD while statistically controlling for any potential confounders. Results: In the multiple regression model, age ( p = 0.006, β = −0.030, 95% CI = −0.051, −0.009) and total time in sedentary bouts > 1 hour ( p = 0.031, β = −0.005, 95% CI = −0.009, −0.001) were independent predictors of relative FMD. Age (β = −0.002, 95% CI = −0.003, −0.001), mean blood flow (β = 0.013, 95% CI = 0.002, 0.024), moderate-intensity physical activity (β = 155.9E−5, 95% CI = 22.4E−5, 289.4E−5), sedentary breaks (β = 0.036, 95% CI = 0.007, 0.066), and total time spent in sedentary bouts > 1 hour (β = −25.02E−5, 95% CI = −47.67E−5, −2.378E−5) were predictors of absolute FMD (all, p < 0.047). All independent outcomes remained significant after partially controlling for all other predictor variables (all, p < 0.031). Conclusions: Habitual prolonged sedentary bouts and sedentary breaks, but not total sedentary time, were predictors of popliteal endothelial-dependent vasodilatory function. The patterns by which sedentary time is accumulated may be more important than the total sedentary time on lower-limb arterial health.

show abstract

Section: Discussionmentioning

confidence: 99%

Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults

et al. 2022

View full text Add to dashboard Cite

show abstract

“…The findings of the present study are strengthened by the inclusion of a large heterogeneous sample and by studying an artery that is prone to the development of peripheral vascular diseases (Debasso et al, 2004;Jadidi et al, 2021). It should be acknowledged that participants were relatively healthy, albeit with an average body mass index within the overweight classification (BMI: 25.0-29.9 kg/m 2 ).…”

Section: Discussionmentioning

confidence: 63%

“…After the abdominal aorta, the popliteal artery is the most common site for aneurysm development (Debasso et al, 2004; Jadidi et al, 2021). Due to its location, the popliteal artery experiences marked reductions in local blood flow during knee‐bent sitting (O'Brien et al, 2019b) that likely contributes to its susceptibility to atherosclerotic development.…”

Section: Discussionmentioning

confidence: 99%

“…The popliteal artery exhibits physiological and geometrical characteristics that contributes to its susceptibility to aneurysm development and peripheral vascular disease (Debasso et al, 2004; Jadidi et al, 2021). The popliteal artery also experiences robust reductions and increases in local blood flow/shear‐stress with prolonged sitting and lower‐limb exercise, respectively (Morishima et al, 2016; O'Brien et al, 2019b).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A larger low‐flow‐mediated constrictor response is associated with augmented flow‐mediated dilation in the popliteal artery

O’Brien

Petterson

Johns

et al. 2021

Clin Physio Funct Imaging

View full text Add to dashboard Cite

Impaired endothelial function is a precursor for the development of arterial diseases (Vanhoutte et al., 2009). Endothelial-dependent dilation is frequently determined via the flow-mediated dilation (FMD) technique, which quantifies the magnitude of vasodilation in response to a reactive hyperaemia provoked by a brief period of distal cuff occlusion (Thijssen et al., 2019). Both upper-(ie brachial) and lower-limb (ie superficial femoral artery) FMD responses provide an index of nitric oxide (NO) biovailability (Green et al., 2014;Kooijman et al., 2008), with larger dilation indicative of a healthier endothelium. A less appreciated and more variable endothelial-dependent

show abstract

“…Moreover, the artery in the Gunter’s canal and behind the knee experiences the greatest load. These deformities are believed to play a major role in damage to the PBA wall and the impairment of blood flow [9]. Under the influence of such deformations, the rigid structure of the stent in the femoropopliteal artery undergoes high stress, which ultimately can lead to fracture of the stent [10,11].…”

Section: Discussionmentioning

confidence: 99%

One-year results of long femoropopliteal lesions stenting with fasciotomy lamina vastoadductoria

Чебан

Osipova

Ignatenko

et al. 2022

Preprint

View full text Add to dashboard Cite

ObjectiveFasciotomy can increase the mobility of the superficial femoral artery and reduce the incidence of stent breakage. This study aimed to compare the long-term patency of drug-eluting nitinol stents with and without fasciotomy in patients with prolonged SFA occlusions.MethodsA randomized clinical trial was conducted in 60 (1:1) patients with long femoropopliteal steno-occlusive lesions more than 200 mm. Patients in group 1 (Zilver) underwent recanalization of occlusion of the femoropopliteal artery with stenting. In group 2 (ZilverFas), recanalization of the femoropopliteal occlusion with stenting and fasciotomy of Gunter’s canal were performed. The follow up evaluation of patency at 6, 12 months.Results12-month primary patency in Zilver and ZilverFas groups was 51% and 80%, respectively (p = 0.02). The freedom from target revascularization (TLR) in Zilver and ZilverFas groups was 50% and 76%, respectively (p = 0.04). At one-years, primary-assisted and secondary patency for the ZilverFas and Zilver groups were 83% versus 62% (p = 0.07), 86% versus 65% (p = 0.05), respectively. In groups Zilver and ZilverFas, the number of stents fracture was 14 and 7, respectively (p = 0.05). The Cox multivariables regression indicated that the stent fracture, diabetes mellitus were the independent predictor of restenosis and reocclusion. Fasciotomy reduced the chance of reocclusion and restenosis by 2.94 times.ConclusionsOur study has shown that a decompressing the stented segment with fasciotomy significantly improves the patency of the femoropopliteal segment and significantly reduces the number and severity of stents fractures.

show abstract

Comparison of morphometric, structural, mechanical, and physiologic characteristics of human superficial femoral and popliteal arteries

Cited by 18 publications

References 87 publications

Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults

Impact of habitual sedentary patterns on popliteal artery endothelial-dependent vasodilation in healthy adults

A larger low‐flow‐mediated constrictor response is associated with augmented flow‐mediated dilation in the popliteal artery

One-year results of long femoropopliteal lesions stenting with fasciotomy lamina vastoadductoria

Contact Info

Product

Resources

About