2011
DOI: 10.1177/153567601101600303
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Comparison of Multiple Systems for Laboratory Whole Room Fumigation

Abstract: Fumigation of high-containment microbiology facilities is an international requirement and in the UnitedKingdom this process is still commonly undertaken using formaldehyde vaporization. Formaldehyde usage is simple and inexpensive, but concerns exist over its toxicity and carcinogenicity. Alternative fumigants exist, although independent, parallel comparison of these substances is limited. This study determined the level of biocidal efficacy achievable with formaldehyde and compared this with other commonly u… Show more

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Cited by 58 publications
(78 citation statements)
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“…The HPV system was faster than the aHP system, as in the study by Fu et al 70 These results indicate that HPV is faster and more effective for biological inactivation than aHP. 69,70,75 However, these studies were not performed in a clinical setting and did not evaluate surface decontamination directly or impact on pathogen transmission.…”
Section: Comparing Systemsmentioning
confidence: 97%
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“…The HPV system was faster than the aHP system, as in the study by Fu et al 70 These results indicate that HPV is faster and more effective for biological inactivation than aHP. 69,70,75 However, these studies were not performed in a clinical setting and did not evaluate surface decontamination directly or impact on pathogen transmission.…”
Section: Comparing Systemsmentioning
confidence: 97%
“…Recent evidence published by Pottage et al and others indicating that catalase-positive bacteria are less susceptible to H 2 O 2 -based NTD systems than bacterial endospores provides a further reason to use stringent challenges for these systems. 70,75,79,80,125 There is a parallel with standards for liquid hospital disinfectants. For example, the EPA requires a hospital disinfectant to achieve a >6-log 10 reduction of certain vegetative bacteria in vitro.…”
Section: Validationmentioning
confidence: 98%
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