Abstract:Despite the advances in diagnosis of leukemia, still we need a rapid and cost-benefi t screening method in patients with acute lymphoblastic leukemia (ALL). The aim of the present study is to evaluate the ability of Multiplex Ligationdependent Probe Amplifi cation (MLPA) method in screening patients with ALL. 45 patients with ALL were selected. DNA were extracted, then PAX5 gene copy number abnormalities (CNAs) were studied by adopting MLPA and QPCR methods. To prove the results of two methods, PCR product fro… Show more
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